ES8502418A1 - Un procedimiento para la preparacion de polipeptidos. - Google Patents

Un procedimiento para la preparacion de polipeptidos.

Info

Publication number
ES8502418A1
ES8502418A1 ES522221A ES522221A ES8502418A1 ES 8502418 A1 ES8502418 A1 ES 8502418A1 ES 522221 A ES522221 A ES 522221A ES 522221 A ES522221 A ES 522221A ES 8502418 A1 ES8502418 A1 ES 8502418A1
Authority
ES
Spain
Prior art keywords
immune modulator
modulator peptides
peptides
igg
enzymatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES522221A
Other languages
English (en)
Other versions
ES522221A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Clinic and Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic and Research Foundation filed Critical Scripps Clinic and Research Foundation
Publication of ES8502418A1 publication Critical patent/ES8502418A1/es
Publication of ES522221A0 publication Critical patent/ES522221A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/866—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving immunoglobulin or antibody fragment, e.g. fab', fab, fv, fc, heavy chain or light chain

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE POLIPEPTIDOS.CONSISTE EN HACER REACCIONAR UN PEPTIDO DE FORMULA (II) CON UN ACIDO FUERTE SELECCIONADO ENTRE ACIDO FLUORHIDRICO LIQUIDO, ACIDO CLORHIDRICO EN ACIDO ACETICO GLACIAL Y ACIDO FORMICO, SUPERIOR AL 95, PARA OBTENER POLIPEPTIDOS DE FORMULA (I), DONDE R ES OH O NR3R4; R3 Y R4 SON H O ALQUILO DE C 1 A 3; R5 ES H, ALQUILO DE C 1 A 3 O UN GRUPO DE BLOQUEO DEL BAB-AMINO; R6 ES H O UN GRUPO PROTECTOR DEL HIDROXI; R7 ES H, UN GRUPO PROTECTOR DEL AMINO O DEL HIDROXI; R8 ES H O UN GRUPO PROTECTOR DEL AMINO; R9 ES H O UN GRUPO PROTECTOR DEL AMINO HIDROXI O CARBOXILO; R10 ES H O UN GRUPO PROTECTOR DEL CARBOXILO; R11 ES H O UN GRUPO PROTECTOR DEL CARBOXILO O AMINO; Y Z ES HIDROXI O NR3R4.
ES522221A 1982-05-11 1983-05-09 Un procedimiento para la preparacion de polipeptidos. Granted ES522221A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/377,223 US4415493A (en) 1982-05-11 1982-05-11 Immune modulator peptides

Publications (2)

Publication Number Publication Date
ES8502418A1 true ES8502418A1 (es) 1985-01-01
ES522221A0 ES522221A0 (es) 1985-01-01

Family

ID=23488251

Family Applications (1)

Application Number Title Priority Date Filing Date
ES522221A Granted ES522221A0 (es) 1982-05-11 1983-05-09 Un procedimiento para la preparacion de polipeptidos.

Country Status (21)

Country Link
US (1) US4415493A (es)
EP (1) EP0094233B1 (es)
JP (1) JPS58206545A (es)
KR (1) KR860001216B1 (es)
AR (1) AR240327A1 (es)
AT (1) ATE15211T1 (es)
AU (1) AU555896B2 (es)
DD (1) DD210259A5 (es)
DE (1) DE3360663D1 (es)
DK (1) DK201383A (es)
ES (1) ES522221A0 (es)
FI (1) FI78918C (es)
GB (1) GB2120253B (es)
GR (1) GR78858B (es)
IE (1) IE54905B1 (es)
IL (1) IL68562A0 (es)
NZ (1) NZ204097A (es)
PH (1) PH17862A (es)
PL (1) PL241894A1 (es)
PT (1) PT76648B (es)
ZA (1) ZA833109B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3224379A1 (de) * 1982-06-30 1984-01-12 Hoechst Ag, 6230 Frankfurt Nonapeptid mit immunstimulierender wirkung, verfahren zu dessen herstellung und dessen verwendung
US4752601A (en) * 1983-08-12 1988-06-21 Immunetech Pharmaceuticals Method of blocking immune complex binding to immunoglobulin FC receptors
US4579840A (en) * 1983-08-12 1986-04-01 Immunetech Pharmaceuticals Method of blocking immune complex binding to immunoglobulin Fc receptors
US4686282A (en) * 1983-08-12 1987-08-11 Immunetech, Inc. Immunotherapeutic polypeptide agents which block immune complex binding to immunoglobulin Fc receptors
US4683292A (en) * 1983-08-12 1987-07-28 Immunetech, Inc. Immunotherapeutic polypeptide agents which bind to lymphocyte immunoglobulin FC receptors
US4683221A (en) * 1986-01-09 1987-07-28 Scripps Clinic And Research Foundation Lymphocyte-activating polypeptides
EP0284898A3 (de) * 1987-04-02 1990-06-27 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Hinge-Peptid, Verfahren zu seiner Herstellung und seine Verwendung zur Herstellung synthetischer Immunogene
US5422258A (en) * 1987-12-31 1995-06-06 Tanox Biosystems, Inc. Methods for producing high affinity anti-human IgE-monoclonal antibodies which binds to IgE on IgEabearing B cells but not basophils
US5449760A (en) * 1987-12-31 1995-09-12 Tanox Biosystems, Inc. Monoclonal antibodies that bind to soluble IGE but do not bind IGE on IGE expressing B lymphocytes or basophils
GB0007588D0 (en) * 2000-03-30 2000-05-17 Univ Nottingham N-Acyl homoserine lactones

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0035454A3 (en) * 1980-02-28 1982-03-03 Genentech, Inc. Desacetylthymosin alpha 1, its process of preparation and its use

Also Published As

Publication number Publication date
GB2120253A (en) 1983-11-30
PT76648B (en) 1986-03-18
IL68562A0 (en) 1983-09-30
ES522221A0 (es) 1985-01-01
ZA833109B (en) 1984-12-24
IE54905B1 (en) 1990-03-14
GR78858B (es) 1984-10-02
DK201383A (da) 1983-11-12
IE831044L (en) 1983-11-11
US4415493A (en) 1983-11-15
KR840004784A (ko) 1984-10-24
FI831496A0 (fi) 1983-05-02
FI78918B (fi) 1989-06-30
EP0094233B1 (en) 1985-08-28
EP0094233A1 (en) 1983-11-16
FI831496L (fi) 1983-11-12
ATE15211T1 (de) 1985-09-15
NZ204097A (en) 1987-05-29
GB2120253B (en) 1985-08-29
FI78918C (fi) 1989-10-10
PT76648A (en) 1983-06-01
AU1432883A (en) 1983-11-17
DE3360663D1 (en) 1985-10-03
AR240327A1 (es) 1990-03-30
AU555896B2 (en) 1986-10-16
DD210259A5 (de) 1984-06-06
KR860001216B1 (ko) 1986-08-27
JPS58206545A (ja) 1983-12-01
PL241894A1 (en) 1984-08-27
DK201383D0 (da) 1983-05-05
GB8312679D0 (en) 1983-06-15
PH17862A (en) 1985-01-09

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