ES8504201A1 - Procedimiento para la preparacion de nuevos derivados de sinergistinas - Google Patents

Procedimiento para la preparacion de nuevos derivados de sinergistinas

Info

Publication number
ES8504201A1
ES8504201A1 ES534313A ES534313A ES8504201A1 ES 8504201 A1 ES8504201 A1 ES 8504201A1 ES 534313 A ES534313 A ES 534313A ES 534313 A ES534313 A ES 534313A ES 8504201 A1 ES8504201 A1 ES 8504201A1
Authority
ES
Spain
Prior art keywords
procedure
preparation
new
general formula
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES534313A
Other languages
English (en)
Other versions
ES534313A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Publication of ES534313A0 publication Critical patent/ES534313A0/es
Publication of ES8504201A1 publication Critical patent/ES8504201A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/19Antibiotic
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/27Cyclic peptide or cyclic protein

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Emergency Protection Circuit Devices (AREA)
  • Suspension Of Electric Lines Or Cables (AREA)
  • Measurement Of Force In General (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS DERIVADOS DE SINERGISTINAS.CONSISTE EN HACER REACCIONAR UN PRODUCTO DE FORMULA GENERAL (R-H) CON UN PRODUCTO DE FORMULA GENERAL (II) EN UN DISOLVENTE ORGANICO COMO METANOL O UN DISOLVENTE DORADO Y A UNA TEMPERATURA ENTRE 0JC Y LA TEMPERATURA DEL REFLUJO DE LA MEZCLA, PARA OBTENER UN COMPUESTO DE FORMULA GENERAL (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. SIENDO: Y, H O UN RADICAL DIEMTILAMINO; R1 Y R2 UN ATOMO DE H Y R, UN RADICAL PIRROLIDINIL-3 TIO, O UN RADICAL ALQUILTIO SUSTITUIDO POR UNO O DOS RADICALES HIDROXISULFONILO U OTROS.SE UTILIZAN PARA EL TRATAMIENTO DE AFECCIONES POR BACTERIAS GRAM-POSITIVAS.
ES534313A 1983-07-13 1984-07-13 Procedimiento para la preparacion de nuevos derivados de sinergistinas Expired ES8504201A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8311705A FR2549063B1 (fr) 1983-07-13 1983-07-13 Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
ES534313A0 ES534313A0 (es) 1985-04-01
ES8504201A1 true ES8504201A1 (es) 1985-04-01

Family

ID=9290812

Family Applications (3)

Application Number Title Priority Date Filing Date
ES534313A Expired ES8504201A1 (es) 1983-07-13 1984-07-13 Procedimiento para la preparacion de nuevos derivados de sinergistinas
ES537179A Expired ES8601210A1 (es) 1983-07-13 1984-10-29 Procedimiento para la preparacion de nuevos derivados de sinergistinas
ES537180A Expired ES8601211A1 (es) 1983-07-13 1984-10-29 Procedimiento para la preparacion de nuevos derivados de sinergistinas

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES537179A Expired ES8601210A1 (es) 1983-07-13 1984-10-29 Procedimiento para la preparacion de nuevos derivados de sinergistinas
ES537180A Expired ES8601211A1 (es) 1983-07-13 1984-10-29 Procedimiento para la preparacion de nuevos derivados de sinergistinas

Country Status (17)

Country Link
US (1) US4618599A (es)
EP (1) EP0133097B1 (es)
JP (1) JPS6038386A (es)
KR (1) KR910005848B1 (es)
AT (1) ATE25691T1 (es)
AU (1) AU567570B2 (es)
CA (1) CA1213583A (es)
DE (1) DE3462507D1 (es)
DK (1) DK169258B1 (es)
ES (3) ES8504201A1 (es)
FI (2) FI78105C (es)
FR (1) FR2549063B1 (es)
GR (1) GR81555B (es)
IL (1) IL72397A (es)
PT (1) PT78894B (es)
SU (3) SU1421260A3 (es)
ZA (1) ZA845316B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2549065B1 (fr) * 1983-07-13 1985-10-25 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2599036B1 (fr) * 1986-05-22 1988-09-09 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2655343B1 (fr) * 1989-12-05 1992-05-07 Rhone Poulenc Sante Procede de preparation de synergistine.
FR2664894A1 (fr) * 1990-07-19 1992-01-24 Rhone Poulenc Sante Nouveaux derives de streptogramines et leur preparation.
IL121821A (en) * 1993-02-17 2000-02-17 Rhone Poulenc Rorer Sa Process for purifying a group A minority component of streptogramin some such purified components and their uses
FR2723373B1 (fr) 1994-08-02 1996-09-13 Rhone Poulenc Rorer Sa Forme purifiee de streptogramines, sa preparation et les compositions pharmaceutiques qui la contiennent
FR2796949B1 (fr) * 1999-07-27 2001-09-21 Aventis Pharma Sa Derives de streptogramines, leur preparation et les compositions qui les contiennent
US20100120855A1 (en) * 2005-07-29 2010-05-13 Tibotec Pharmaceuticals Ltd. Macrocylic inhibitors of hepatitis c virus
JP2008057849A (ja) * 2006-08-31 2008-03-13 Denso Corp 熱交換器の製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4355112A (en) * 1977-06-06 1982-10-19 Sanraku-Ocean Co., Ltd. Streptomyces culture

Also Published As

Publication number Publication date
FI80456C (fi) 1990-06-11
FI78105C (fi) 1989-06-12
IL72397A (en) 1987-10-30
FI842812A0 (fi) 1984-07-12
FR2549063B1 (fr) 1985-10-25
PT78894A (fr) 1984-08-01
US4618599A (en) 1986-10-21
DK342584A (da) 1985-01-14
FI874654A7 (fi) 1987-10-22
GR81555B (es) 1984-12-11
DK342584D0 (da) 1984-07-12
SU1456019A3 (ru) 1989-01-30
PT78894B (fr) 1986-08-08
ATE25691T1 (de) 1987-03-15
ES537179A0 (es) 1985-10-16
ZA845316B (en) 1985-02-27
ES537180A0 (es) 1985-10-16
ES8601210A1 (es) 1985-10-16
DE3462507D1 (en) 1987-04-09
FI78105B (fi) 1989-02-28
AU567570B2 (en) 1987-11-26
FI80456B (fi) 1990-02-28
SU1421260A3 (ru) 1988-08-30
ES8601211A1 (es) 1985-10-16
KR910005848B1 (ko) 1991-08-05
FR2549063A1 (fr) 1985-01-18
FI842812A7 (fi) 1985-01-14
JPH0522718B2 (es) 1993-03-30
JPS6038386A (ja) 1985-02-27
SU1445560A3 (ru) 1988-12-15
ES534313A0 (es) 1985-04-01
FI874654A0 (fi) 1987-10-22
IL72397A0 (en) 1984-11-30
CA1213583A (fr) 1986-11-04
AU3047284A (en) 1985-01-17
EP0133097A1 (fr) 1985-02-13
KR850001212A (ko) 1985-03-16
DK169258B1 (da) 1994-09-26
EP0133097B1 (fr) 1987-03-04

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