ES8504201A1 - Procedimiento para la preparacion de nuevos derivados de sinergistinas - Google Patents
Procedimiento para la preparacion de nuevos derivados de sinergistinasInfo
- Publication number
- ES8504201A1 ES8504201A1 ES534313A ES534313A ES8504201A1 ES 8504201 A1 ES8504201 A1 ES 8504201A1 ES 534313 A ES534313 A ES 534313A ES 534313 A ES534313 A ES 534313A ES 8504201 A1 ES8504201 A1 ES 8504201A1
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- preparation
- new
- general formula
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 abstract 1
- 241000192125 Firmicutes Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/19—Antibiotic
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Emergency Protection Circuit Devices (AREA)
- Suspension Of Electric Lines Or Cables (AREA)
- Measurement Of Force In General (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS DERIVADOS DE SINERGISTINAS.CONSISTE EN HACER REACCIONAR UN PRODUCTO DE FORMULA GENERAL (R-H) CON UN PRODUCTO DE FORMULA GENERAL (II) EN UN DISOLVENTE ORGANICO COMO METANOL O UN DISOLVENTE DORADO Y A UNA TEMPERATURA ENTRE 0JC Y LA TEMPERATURA DEL REFLUJO DE LA MEZCLA, PARA OBTENER UN COMPUESTO DE FORMULA GENERAL (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. SIENDO: Y, H O UN RADICAL DIEMTILAMINO; R1 Y R2 UN ATOMO DE H Y R, UN RADICAL PIRROLIDINIL-3 TIO, O UN RADICAL ALQUILTIO SUSTITUIDO POR UNO O DOS RADICALES HIDROXISULFONILO U OTROS.SE UTILIZAN PARA EL TRATAMIENTO DE AFECCIONES POR BACTERIAS GRAM-POSITIVAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8311705A FR2549063B1 (fr) | 1983-07-13 | 1983-07-13 | Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES534313A0 ES534313A0 (es) | 1985-04-01 |
| ES8504201A1 true ES8504201A1 (es) | 1985-04-01 |
Family
ID=9290812
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES534313A Expired ES8504201A1 (es) | 1983-07-13 | 1984-07-13 | Procedimiento para la preparacion de nuevos derivados de sinergistinas |
| ES537179A Expired ES8601210A1 (es) | 1983-07-13 | 1984-10-29 | Procedimiento para la preparacion de nuevos derivados de sinergistinas |
| ES537180A Expired ES8601211A1 (es) | 1983-07-13 | 1984-10-29 | Procedimiento para la preparacion de nuevos derivados de sinergistinas |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES537179A Expired ES8601210A1 (es) | 1983-07-13 | 1984-10-29 | Procedimiento para la preparacion de nuevos derivados de sinergistinas |
| ES537180A Expired ES8601211A1 (es) | 1983-07-13 | 1984-10-29 | Procedimiento para la preparacion de nuevos derivados de sinergistinas |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4618599A (es) |
| EP (1) | EP0133097B1 (es) |
| JP (1) | JPS6038386A (es) |
| KR (1) | KR910005848B1 (es) |
| AT (1) | ATE25691T1 (es) |
| AU (1) | AU567570B2 (es) |
| CA (1) | CA1213583A (es) |
| DE (1) | DE3462507D1 (es) |
| DK (1) | DK169258B1 (es) |
| ES (3) | ES8504201A1 (es) |
| FI (2) | FI78105C (es) |
| FR (1) | FR2549063B1 (es) |
| GR (1) | GR81555B (es) |
| IL (1) | IL72397A (es) |
| PT (1) | PT78894B (es) |
| SU (3) | SU1421260A3 (es) |
| ZA (1) | ZA845316B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2549065B1 (fr) * | 1983-07-13 | 1985-10-25 | Rhone Poulenc Sante | Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2599036B1 (fr) * | 1986-05-22 | 1988-09-09 | Rhone Poulenc Sante | Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2655343B1 (fr) * | 1989-12-05 | 1992-05-07 | Rhone Poulenc Sante | Procede de preparation de synergistine. |
| FR2664894A1 (fr) * | 1990-07-19 | 1992-01-24 | Rhone Poulenc Sante | Nouveaux derives de streptogramines et leur preparation. |
| IL121821A (en) * | 1993-02-17 | 2000-02-17 | Rhone Poulenc Rorer Sa | Process for purifying a group A minority component of streptogramin some such purified components and their uses |
| FR2723373B1 (fr) | 1994-08-02 | 1996-09-13 | Rhone Poulenc Rorer Sa | Forme purifiee de streptogramines, sa preparation et les compositions pharmaceutiques qui la contiennent |
| FR2796949B1 (fr) * | 1999-07-27 | 2001-09-21 | Aventis Pharma Sa | Derives de streptogramines, leur preparation et les compositions qui les contiennent |
| US20100120855A1 (en) * | 2005-07-29 | 2010-05-13 | Tibotec Pharmaceuticals Ltd. | Macrocylic inhibitors of hepatitis c virus |
| JP2008057849A (ja) * | 2006-08-31 | 2008-03-13 | Denso Corp | 熱交換器の製造方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4355112A (en) * | 1977-06-06 | 1982-10-19 | Sanraku-Ocean Co., Ltd. | Streptomyces culture |
-
1983
- 1983-07-13 FR FR8311705A patent/FR2549063B1/fr not_active Expired
-
1984
- 1984-07-10 ZA ZA845316A patent/ZA845316B/xx unknown
- 1984-07-10 AU AU30472/84A patent/AU567570B2/en not_active Ceased
- 1984-07-11 KR KR1019840004023A patent/KR910005848B1/ko not_active Expired
- 1984-07-11 GR GR75264A patent/GR81555B/el unknown
- 1984-07-12 DE DE8484401478T patent/DE3462507D1/de not_active Expired
- 1984-07-12 CA CA000458721A patent/CA1213583A/fr not_active Expired
- 1984-07-12 US US06/630,288 patent/US4618599A/en not_active Expired - Lifetime
- 1984-07-12 JP JP59143403A patent/JPS6038386A/ja active Granted
- 1984-07-12 IL IL8472397A patent/IL72397A/xx unknown
- 1984-07-12 FI FI842812A patent/FI78105C/fi not_active IP Right Cessation
- 1984-07-12 DK DK342584A patent/DK169258B1/da not_active IP Right Cessation
- 1984-07-12 PT PT78894A patent/PT78894B/pt unknown
- 1984-07-12 AT AT84401478T patent/ATE25691T1/de not_active IP Right Cessation
- 1984-07-12 EP EP84401478A patent/EP0133097B1/fr not_active Expired
- 1984-07-12 SU SU843760756A patent/SU1421260A3/ru active
- 1984-07-13 ES ES534313A patent/ES8504201A1/es not_active Expired
- 1984-10-29 ES ES537179A patent/ES8601210A1/es not_active Expired
- 1984-10-29 ES ES537180A patent/ES8601211A1/es not_active Expired
-
1985
- 1985-12-06 SU SU853984703A patent/SU1456019A3/ru active
- 1985-12-06 SU SU853984289A patent/SU1445560A3/ru active
-
1987
- 1987-10-22 FI FI874654A patent/FI80456C/fi not_active IP Right Cessation
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