ES8505202A1 - Un procedimiento para la preparacion de nuevos 5-amino o amino sustituidos-imidazoles. - Google Patents

Un procedimiento para la preparacion de nuevos 5-amino o amino sustituidos-imidazoles.

Info

Publication number
ES8505202A1
ES8505202A1 ES528159A ES528159A ES8505202A1 ES 8505202 A1 ES8505202 A1 ES 8505202A1 ES 528159 A ES528159 A ES 528159A ES 528159 A ES528159 A ES 528159A ES 8505202 A1 ES8505202 A1 ES 8505202A1
Authority
ES
Spain
Prior art keywords
amino
imidazoles
procedure
preparation
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES528159A
Other languages
English (en)
Other versions
ES528159A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES528159A0 publication Critical patent/ES528159A0/es
Publication of ES8505202A1 publication Critical patent/ES8505202A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS 5-AMINO O AMINO SUSTITUIDO-IMIDAZOLES, DE FORMULA GENERAL (I), EN LA QUE R1 ES FENILO MONOSUSTITUIDO O POLISUSTITUIDO; R2 ES AMINO; R3 ES CARBAMOILO, CIANO O AMIDINO; Y R4 ES HIDROGENO O HIDROXI.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (II) CON UN HALURO DE R1, EN PRESENCIA DE UNA BASE Y A UNA TEMPERATURA COMPRENDIDA ENTRE LA AMBIENTE Y 100 GRADOS.DE APLICACION EN EL TRATAMIENTO DE LA COCCIDIOSIS CECAL O INTESTINAL DE LAS AVES DE CORRAL.
ES528159A 1982-12-20 1983-12-19 Un procedimiento para la preparacion de nuevos 5-amino o amino sustituidos-imidazoles. Expired ES8505202A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45084882A 1982-12-20 1982-12-20

Publications (2)

Publication Number Publication Date
ES528159A0 ES528159A0 (es) 1985-05-16
ES8505202A1 true ES8505202A1 (es) 1985-05-16

Family

ID=23789738

Family Applications (1)

Application Number Title Priority Date Filing Date
ES528159A Expired ES8505202A1 (es) 1982-12-20 1983-12-19 Un procedimiento para la preparacion de nuevos 5-amino o amino sustituidos-imidazoles.

Country Status (8)

Country Link
EP (1) EP0113570B1 (es)
JP (1) JPS59118772A (es)
AT (1) ATE25521T1 (es)
CA (1) CA1245660A (es)
DE (1) DE3369845D1 (es)
DK (1) DK584283A (es)
ES (1) ES8505202A1 (es)
IE (1) IE56381B1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59167515A (ja) * 1983-03-15 1984-09-21 Ajinomoto Co Inc 免疫機能増強剤
EP0151528B1 (en) * 1984-02-02 1990-07-04 Merck & Co. Inc. 5-(amino or substituted amino)-1,2,3-triazoles
DE3627155A1 (de) * 1986-08-11 1988-02-18 Schering Ag Imidazol-derivate
FI91754C (fi) * 1986-12-02 1994-08-10 Tanabe Seiyaku Co Analogiamenetelmä lääkeaineena käyttökelpoisen imidatsolijohdannaisen valmistamiseksi
CA1329614C (en) * 1987-05-02 1994-05-17 Rainer Buerstinghaus N-substituted azoles
US5359078A (en) * 1989-05-19 1994-10-25 The United States Of America As Represented By The Department Of Health And Human Services Signal transduction inhibitor compounds
US5635521A (en) * 1991-09-23 1997-06-03 Sandoz Ltd. Imidazolylmethyl-pyridines
KR100401283B1 (ko) * 1998-07-13 2003-12-31 주식회사유한양행 라스변이세포성장억제구아니딘유도체
CA2434300A1 (en) * 2001-01-18 2002-07-25 Schering Corporation Synthesis of temozolomide and analogs
CA2434308C (en) 2001-01-18 2010-09-21 Schering Corporation Synthesis of temozolomide and analogs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4265900A (en) * 1979-10-29 1981-05-05 Mcneilab, Inc. N-Aryl-N'-imidazol-2-ylureas
JPS5671074A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative

Also Published As

Publication number Publication date
JPS59118772A (ja) 1984-07-09
EP0113570B1 (en) 1987-02-25
ES528159A0 (es) 1985-05-16
DK584283D0 (da) 1983-12-19
EP0113570A1 (en) 1984-07-18
DK584283A (da) 1984-06-21
ATE25521T1 (de) 1987-03-15
DE3369845D1 (en) 1987-04-02
IE832975L (en) 1984-06-20
CA1245660A (en) 1988-11-29
IE56381B1 (en) 1991-07-17

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401