ES8506092A1 - Un metodo de producir un precursor del factor de liberacion de la hormona del crecimiento humana - Google Patents
Un metodo de producir un precursor del factor de liberacion de la hormona del crecimiento humanaInfo
- Publication number
- ES8506092A1 ES8506092A1 ES534002A ES534002A ES8506092A1 ES 8506092 A1 ES8506092 A1 ES 8506092A1 ES 534002 A ES534002 A ES 534002A ES 534002 A ES534002 A ES 534002A ES 8506092 A1 ES8506092 A1 ES 8506092A1
- Authority
- ES
- Spain
- Prior art keywords
- precursor
- host cells
- dna encoding
- grfh
- way
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002243 precursor Substances 0.000 title abstract 4
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 102000002265 Human Growth Hormone Human genes 0.000 abstract 1
- 108010000521 Human Growth Hormone Proteins 0.000 abstract 1
- 239000000854 Human Growth Hormone Substances 0.000 abstract 1
- 150000001413 amino acids Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCEDIMIENTO PARA LA PRODUCCION DE UN PRECURSOR DEL FACTOR DE LIBERACION DE LA HORMONA DEL CRECIMIENTO HUMANO.COMPRENDEE LAS SIGUIENTES OPERACIONES: PRIMERA, SE PROPORCIONA UNA SECUENCIA DE ADN QUE TIENE CODIFICADO UN POLIPEPTIDO PRECURSOR DE GRFH CON UNA SECUENCIA DE AMINOACIDOS DE FORMULA (I); SEGUNDA, SE TRANSFORMAN LAS CELULAS HOSPEDADORAS CON DICHA SECUENCIA DE ADN, DE TAL MANERA QUE DICHAS CELULAS HOSPEDADORAS EXPRESEN EL POLIPEPTIDO CODIFICADO; Y POR ULTIMO, SE CULTIVAN DICHAS CELULAS HOSPEDADORAS DE TAL MANERA QUE SE EXPRESE EL POLIPEPTIDO PRECURSOR DE GRFH.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51093583A | 1983-07-05 | 1983-07-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8506092A1 true ES8506092A1 (es) | 1985-06-16 |
| ES534002A0 ES534002A0 (es) | 1985-06-16 |
Family
ID=24032800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES534002A Granted ES534002A0 (es) | 1983-07-05 | 1984-07-04 | Un metodo de producir un precursor del factor de liberacion de la hormona del crecimiento humana |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0134085A1 (es) |
| JP (1) | JP2506322B2 (es) |
| KR (1) | KR850001281A (es) |
| AU (1) | AU571542B2 (es) |
| CA (1) | CA1299119C (es) |
| DK (1) | DK313784A (es) |
| ES (1) | ES534002A0 (es) |
| FI (1) | FI81378C (es) |
| GR (1) | GR82239B (es) |
| HU (1) | HU197939B (es) |
| IL (1) | IL72299A (es) |
| MX (1) | MX167047B (es) |
| NO (1) | NO842682L (es) |
| NZ (1) | NZ208633A (es) |
| PH (1) | PH22584A (es) |
| PT (1) | PT78833B (es) |
| ZA (1) | ZA844380B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3327007A1 (de) * | 1983-07-27 | 1985-02-07 | Hoechst Ag, 6230 Frankfurt | Herstellung von polypeptiden mit einem saeureamid-carboxyterminus |
| NZ213759A (en) * | 1984-10-19 | 1989-01-27 | Genentech Inc | Lhrh-ctp protein conjugates influencing prolactin fsh and lh release |
| US4828988A (en) * | 1986-05-15 | 1989-05-09 | Smith Kline - Rit | Hybrid polypeptides comprising somatocrinine and alpha1 -antitrypsin, method for their production from bacterial clones and use thereof for the production of somatocrinine |
| JPS63123386A (ja) * | 1986-11-14 | 1988-05-27 | Japan Tobacco Inc | 植物ウイルス阻害物質の製造方法 |
| NZ242344A (en) * | 1991-04-19 | 1993-11-25 | Lilly Co Eli | Dna encoding bovine growth hormone releasing factor and precursors, the polypeptide precursor and pharmaceutical compositions |
| US5512459A (en) * | 1993-07-20 | 1996-04-30 | Bionebraska, Inc. | Enzymatic method for modification or recombinant polypeptides |
| CA2297375A1 (en) | 1997-07-24 | 1999-02-04 | Valentis, Inc. | Ghrh expression system and methods of use |
| DE602005027661D1 (de) * | 2004-01-20 | 2011-06-09 | VGX Pharmaceuticals LLC | Isetzendem hormon (ghrh) aus muskelzellen durch speziesspezifisches signalpeptid |
| KR102461139B1 (ko) * | 2020-01-22 | 2022-11-01 | 태경에코 주식회사 | 대기오염물질의 배출저감 연탄 및 그의 제조방법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA802992B (en) * | 1979-06-01 | 1981-10-28 | Univ California | Human pre-growth hormone |
| US4563352A (en) * | 1982-10-04 | 1986-01-07 | The Salk Institute For Biological Studies | Human pancreatic GRF |
| DE3381567D1 (de) * | 1982-11-04 | 1990-06-21 | Hoffmann La Roche | Hestellung von rekombinanten wachstumsausloesenden faktoren. |
-
1984
- 1984-06-08 ZA ZA844380A patent/ZA844380B/xx unknown
- 1984-06-21 AU AU29733/84A patent/AU571542B2/en not_active Ceased
- 1984-06-22 CA CA000457226A patent/CA1299119C/en not_active Expired - Lifetime
- 1984-06-22 NZ NZ208633A patent/NZ208633A/en unknown
- 1984-06-27 DK DK313784A patent/DK313784A/da not_active Application Discontinuation
- 1984-07-02 PT PT78833A patent/PT78833B/pt not_active IP Right Cessation
- 1984-07-02 FI FI842664A patent/FI81378C/fi not_active IP Right Cessation
- 1984-07-03 NO NO842682A patent/NO842682L/no unknown
- 1984-07-03 GR GR75175A patent/GR82239B/el unknown
- 1984-07-03 PH PH30909A patent/PH22584A/en unknown
- 1984-07-04 IL IL72299A patent/IL72299A/xx not_active IP Right Cessation
- 1984-07-04 HU HU842618A patent/HU197939B/hu not_active IP Right Cessation
- 1984-07-04 ES ES534002A patent/ES534002A0/es active Granted
- 1984-07-04 KR KR1019840003859A patent/KR850001281A/ko not_active Ceased
- 1984-07-04 EP EP84304581A patent/EP0134085A1/en not_active Withdrawn
- 1984-07-05 MX MX026446A patent/MX167047B/es unknown
- 1984-07-05 JP JP59139738A patent/JP2506322B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT78833A (en) | 1984-08-01 |
| PT78833B (en) | 1986-06-02 |
| DK313784D0 (da) | 1984-06-27 |
| HU197939B (en) | 1989-06-28 |
| CA1299119C (en) | 1992-04-21 |
| FI81378B (fi) | 1990-06-29 |
| NO842682L (no) | 1985-01-07 |
| JPS6037990A (ja) | 1985-02-27 |
| JP2506322B2 (ja) | 1996-06-12 |
| FI81378C (fi) | 1990-10-10 |
| EP0134085A1 (en) | 1985-03-13 |
| FI842664L (fi) | 1985-01-06 |
| KR850001281A (ko) | 1985-03-18 |
| NZ208633A (en) | 1987-09-30 |
| AU2973384A (en) | 1985-01-10 |
| ES534002A0 (es) | 1985-06-16 |
| AU571542B2 (en) | 1988-04-21 |
| GR82239B (es) | 1984-12-13 |
| IL72299A (en) | 1990-12-23 |
| ZA844380B (en) | 1985-01-30 |
| PH22584A (en) | 1988-10-17 |
| HUT35009A (en) | 1985-05-28 |
| FI842664A0 (fi) | 1984-07-02 |
| IL72299A0 (en) | 1984-11-30 |
| DK313784A (da) | 1985-01-06 |
| MX167047B (es) | 1993-02-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU630951B2 (en) | Enzymatic removal of a protein amino-terminal sequence | |
| AU595290B2 (en) | Process for producing human epidermal growth factor and analogs thereof | |
| NO174351C (no) | Fremgangsmåte for fremstilling av human insulinforlöper samt DNA-sekvens og vektor til anvendelse av fremgangsmåten | |
| ES2056817T3 (es) | Transformacion de trichoderma. | |
| DE3752319D1 (de) | Prozess zur rekombinanten Herstellung von HIV-2 - Proteinen sowie Zellen, die HIV-2 - Proteine exprimiert | |
| DK521283A (da) | Middel til kosmetisk hudpleje og fremgangsmaade til dets fremstilling | |
| GB2197324B (en) | Process for the production of a polypeptide | |
| AR241314A1 (es) | Aislado de adn, vector en base en dicho aislado cultivo de celulas tratadas con dicho vector y preparacion de factor viii humano funcional. | |
| ES8507179A1 (es) | Un metodo de conseguir una deseada proteina madura en una celula hospedante de vertebrado. | |
| AR017510A1 (es) | Polinucleotido aislado o recombinante, vector de expresion, celula huesped, metodo para preparar un polipeptido antigenico, metodo y equipo para ladeteccion de un polinucleotido, compuesto de union, metodo de empleo del compuesto de union, polipeptido antigenico aislado o substancialmente puro, ymet | |
| NO167295C (no) | Fremgangsmaate for fremstilling av et terapeutisk aktivt peptid. | |
| DE3878231D1 (de) | Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung. | |
| EP0218531A3 (en) | Immunogenic peptides of human interleukin-1 and the corresponding anti-peptide antibodies | |
| ATE63750T1 (de) | Peptid, dessen herstellung und benutzung. | |
| MY102257A (en) | Production and use of a novel t-cell suppressor factor | |
| EP0236978A3 (en) | Production of factor xiiia by gene technology | |
| KR850001287A (ko) | 폴리펩타이드의 제조방법 | |
| ES2061619T3 (es) | Metodo mejorado para la preparacion de la hormona de crecimiento humano natural en forma pura. | |
| EP0315118A3 (en) | Dna coding for endothelin and use thereof | |
| ES2061524T3 (es) | Un vector plasmidico para la expresion en bacillus y empleado para la clonacion del gen estructural que codifica la hormona de crecimiento humana y un metodo para la produccion de la hormona. | |
| JPS5775960A (en) | Purified polypeptide | |
| NO921489L (no) | Forloeperformer av bovin veksthormon-frigjoerende faktor ogbeslektede dna-forbindelser | |
| ATE110112T1 (de) | Verfahren und systeme zur herstellung von hiv- antigenen. | |
| ATE49401T1 (de) | Verfahren zur herstellung von alkylarylethern. | |
| ATE91303T1 (de) | Verfahren zur herstellung von peptiden durch spezifische spaltung von gentechnisch gewonnenen fusionsproteinen mit collagenasen. |