ES8506701A1 - Un procedimiento para preparar nuevas 5-aminometil-imidazol-1-il-1,3-dialquil-1h-pirazol-4-il-aroil-metanonas - Google Patents

Un procedimiento para preparar nuevas 5-aminometil-imidazol-1-il-1,3-dialquil-1h-pirazol-4-il-aroil-metanonas

Info

Publication number
ES8506701A1
ES8506701A1 ES535795A ES535795A ES8506701A1 ES 8506701 A1 ES8506701 A1 ES 8506701A1 ES 535795 A ES535795 A ES 535795A ES 535795 A ES535795 A ES 535795A ES 8506701 A1 ES8506701 A1 ES 8506701A1
Authority
ES
Spain
Prior art keywords
pyrazol
imidazol
aminomethyl
dialkyl
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES535795A
Other languages
English (en)
Other versions
ES535795A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of ES535795A0 publication Critical patent/ES535795A0/es
Publication of ES8506701A1 publication Critical patent/ES8506701A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE 5-AMINOMETIL-IMIDAZOL-1-IL-1,3-DIALQUIL-1H-PIRAZOL-4-IL-AROIL-METANONAS, DE FORMULA GENERAL (I), EN LA QUE R1 Y R2 SON ALQUILO CON 1 A 6 ATOMOS DE CARBONO; R3 Y R4 SON HIDROGENO O ALQUILO; R5 Y R6 SON HIDROGENO, ALQUILO O FENIL-ALQUILO; Y AR ES FENILO, Y SUS SALES DE ADICION FARMACEUTICAMENTE ACEPTABLES.CONSISTE EN SOMETER A UNA REACCION DE DESPLAZAMIENTO AL GRUPO HIDROXILO DE UN COMPUESTO DE FORMULA GENERAL (II), CON UNA AMINA DE FORMULA: R5R6NH.DE APLICACION EN EL TRATAMIENTO DE DISFUNCIONES CEREBRALES, TALES COMO LA ARTERIOSCLEROSIS CEREBRAL, APOPLEJIA CEREBRAL Y TRAUMA DE CABEZA.
ES535795A 1983-02-04 1984-09-10 Un procedimiento para preparar nuevas 5-aminometil-imidazol-1-il-1,3-dialquil-1h-pirazol-4-il-aroil-metanonas Expired ES8506701A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46379583A 1983-02-04 1983-02-04

Publications (2)

Publication Number Publication Date
ES535795A0 ES535795A0 (es) 1985-08-01
ES8506701A1 true ES8506701A1 (es) 1985-08-01

Family

ID=23841402

Family Applications (3)

Application Number Title Priority Date Filing Date
ES529446A Granted ES529446A0 (es) 1983-02-04 1984-02-03 Un procedimiento para preparar nuevas 5-aminometil-imidazol-1-il-1, 3-dialquil-1h-pirazol-4-il-aroil-metanonas
ES535795A Expired ES8506701A1 (es) 1983-02-04 1984-09-10 Un procedimiento para preparar nuevas 5-aminometil-imidazol-1-il-1,3-dialquil-1h-pirazol-4-il-aroil-metanonas
ES535794A Expired ES8506700A1 (es) 1983-02-04 1984-09-10 Un procedimiento para preparar nuevas 5-aminometil-imidazol-1-il-1,3-dialquil-1h-pirazol-4-il-aroil-metanonas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES529446A Granted ES529446A0 (es) 1983-02-04 1984-02-03 Un procedimiento para preparar nuevas 5-aminometil-imidazol-1-il-1, 3-dialquil-1h-pirazol-4-il-aroil-metanonas

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES535794A Expired ES8506700A1 (es) 1983-02-04 1984-09-10 Un procedimiento para preparar nuevas 5-aminometil-imidazol-1-il-1,3-dialquil-1h-pirazol-4-il-aroil-metanonas

Country Status (8)

Country Link
EP (1) EP0118205B1 (es)
JP (1) JPS59148782A (es)
AT (1) ATE28457T1 (es)
AU (1) AU559935B2 (es)
DE (1) DE3464915D1 (es)
DK (1) DK46884A (es)
ES (3) ES529446A0 (es)
GR (1) GR79759B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201245155A (en) 2010-09-01 2012-11-16 Du Pont Fungicidal pyrazoles

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1060892A (en) * 1974-11-06 1979-08-21 Parke, Davis And Company Diazepine compounds and method for their production

Also Published As

Publication number Publication date
ES8506637A1 (es) 1985-08-01
GR79759B (es) 1984-10-31
AU2356384A (en) 1984-08-09
DK46884D0 (da) 1984-02-02
JPS59148782A (ja) 1984-08-25
ATE28457T1 (de) 1987-08-15
AU559935B2 (en) 1987-03-26
ES535794A0 (es) 1985-08-01
ES529446A0 (es) 1985-08-01
ES535795A0 (es) 1985-08-01
ES8506700A1 (es) 1985-08-01
EP0118205B1 (en) 1987-07-22
DK46884A (da) 1984-08-05
EP0118205A1 (en) 1984-09-12
DE3464915D1 (en) 1987-08-27

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