ES8507155A3 - Metodo para la obtencion de esteroides de la serie de prednisolona - Google Patents

Metodo para la obtencion de esteroides de la serie de prednisolona

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Publication number
ES8507155A3
ES8507155A3 ES538539A ES538539A ES8507155A3 ES 8507155 A3 ES8507155 A3 ES 8507155A3 ES 538539 A ES538539 A ES 538539A ES 538539 A ES538539 A ES 538539A ES 8507155 A3 ES8507155 A3 ES 8507155A3
Authority
ES
Spain
Prior art keywords
steroid
17alpha
formula
prednisolone
series
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES538539A
Other languages
English (en)
Other versions
ES538539A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Compania Espanola de Sintesis Quimica SA CESQUISA
Original Assignee
Compania Espanola de Sintesis Quimica SA CESQUISA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Compania Espanola de Sintesis Quimica SA CESQUISA filed Critical Compania Espanola de Sintesis Quimica SA CESQUISA
Priority to ES538539A priority Critical patent/ES8507155A3/es
Publication of ES538539A0 publication Critical patent/ES538539A0/es
Publication of ES8507155A3 publication Critical patent/ES8507155A3/es
Expired legal-status Critical Current

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Abstract

PROCEDIMIENTO PARA LA OBTENCION DE ESTEROIDES DE LA SERIE DE PREDNISOLONA, DE FORMULA (I), EN LA QUE Y Y Z PUEDENSER HIDROGENO O UN HALOGENO; Y Z ADEMAS UN ALQUILO INFERIOR.CONSISTE EN LA ORTOESTERIFICACION DE UN ESTEROIDE, DE FORMULA (II) PARA FORMAR UN COMPUESTO DE FORMULA (III), EN LA QUE R Y RK SON GRUPOS ALQUILICO DE 1-6 ATOMOS DE CARBONO; SEGUIDA DE LA HIDROLISIS DEL ORTOESTER PARA FORMAR UN 17BAB-ESTER; ESTERIFICACION DE ESTER PARA FORMAR UN 17BAB,21-DIESTER EN EL QUE EL NUEVO GRUPO ACILO TIENE 2-7 ATOMOS DE CARBONO. ELIMINACION DEL GRUPO 17BAB-ACILOXI; OXIDACION SELECTIVA DEL BDB 16-21-ESTER FORMADO; E HIDROLISIS O ALCOHOLISIS DEL 16BAB,17BAB-DIHIDROXI-21-ESTER, ULTIMAMENTE PRODUCIDO.ESTOS COMPUESTOS TIENEN APLICACIONES PARA FINES TERAPEUTICOS Y COMO INTERMEDIOS PARA LA PREPARACION DE DERIVADOS.
ES538539A 1984-12-12 1984-12-12 Metodo para la obtencion de esteroides de la serie de prednisolona Expired ES8507155A3 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES538539A ES8507155A3 (es) 1984-12-12 1984-12-12 Metodo para la obtencion de esteroides de la serie de prednisolona

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES538539A ES8507155A3 (es) 1984-12-12 1984-12-12 Metodo para la obtencion de esteroides de la serie de prednisolona

Publications (2)

Publication Number Publication Date
ES538539A0 ES538539A0 (es) 1985-09-01
ES8507155A3 true ES8507155A3 (es) 1985-09-01

Family

ID=8488307

Family Applications (1)

Application Number Title Priority Date Filing Date
ES538539A Expired ES8507155A3 (es) 1984-12-12 1984-12-12 Metodo para la obtencion de esteroides de la serie de prednisolona

Country Status (1)

Country Link
ES (1) ES8507155A3 (es)

Also Published As

Publication number Publication date
ES538539A0 (es) 1985-09-01

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