ES8600251A1 - Metodo de preparar nuevos 2-acilamino-5-feniletenilbencimidazoles - Google Patents

Metodo de preparar nuevos 2-acilamino-5-feniletenilbencimidazoles

Info

Publication number
ES8600251A1
ES8600251A1 ES527947A ES527947A ES8600251A1 ES 8600251 A1 ES8600251 A1 ES 8600251A1 ES 527947 A ES527947 A ES 527947A ES 527947 A ES527947 A ES 527947A ES 8600251 A1 ES8600251 A1 ES 8600251A1
Authority
ES
Spain
Prior art keywords
formula
phenylethenylbenzimidazoles
lower alkyl
chlorophormiate
acilamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES527947A
Other languages
English (en)
Other versions
ES527947A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of ES527947A0 publication Critical patent/ES527947A0/es
Publication of ES8600251A1 publication Critical patent/ES8600251A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A01N43/52—1,3-Diazoles; Hydrogenated 1,3-diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/18—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Paper (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Photoreceptors In Electrophotography (AREA)

Abstract

METODO DE PREPARAR NUEVOS 2-ACILAMINO-5-FENILETENILBENCIMIDAZOLES.COMPRENDE: HACER REACCIONAR UN COMPUESTO DE DIAMINO DE FORMULA (II), CON CIANAMIDA Y UN CLOROFORMIATO DE ALQUILO INFERIOR O UN HALURO DE ALCANOILO INFERIOR, PARA OBTENER COMPUESTOS DE FORMULA (I) EN LA CUAL R ES HIDROGENO, HALO, METILO Y OTROS Y R1 ES ALQUILO INFERIOR DE C 1 A 4 ALCOXI INFERIOR DE C 1 A 4.SE UTILIZAN POR SU ACTIVIDAD ANTIHELMINTICA CON UN MINIMO DE EFECTOS SECUNDARIOS.
ES527947A 1982-12-13 1983-12-12 Metodo de preparar nuevos 2-acilamino-5-feniletenilbencimidazoles Expired ES8600251A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/449,350 US4435418A (en) 1982-12-13 1982-12-13 5-Phenylethenylbenzimidazoles

Publications (2)

Publication Number Publication Date
ES527947A0 ES527947A0 (es) 1985-09-16
ES8600251A1 true ES8600251A1 (es) 1985-09-16

Family

ID=23783825

Family Applications (1)

Application Number Title Priority Date Filing Date
ES527947A Expired ES8600251A1 (es) 1982-12-13 1983-12-12 Metodo de preparar nuevos 2-acilamino-5-feniletenilbencimidazoles

Country Status (20)

Country Link
US (1) US4435418A (es)
EP (1) EP0112133B1 (es)
JP (1) JPS59116275A (es)
KR (1) KR840006976A (es)
AT (1) ATE30323T1 (es)
AU (1) AU561969B2 (es)
CA (1) CA1199924A (es)
DE (1) DE3374124D1 (es)
DK (1) DK552883A (es)
EG (1) EG16161A (es)
ES (1) ES8600251A1 (es)
FI (1) FI834550L (es)
GR (1) GR79743B (es)
IL (1) IL70125A (es)
NO (1) NO159380C (es)
NZ (1) NZ206124A (es)
PH (1) PH18341A (es)
PT (1) PT77738B (es)
ZA (1) ZA838262B (es)
ZW (1) ZW23983A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4587361A (en) * 1984-05-07 1986-05-06 Smithkline Beckman Corporation Anthelmintic benzamides
GB9124002D0 (en) * 1991-11-12 1992-01-02 Pfizer Ltd Benzimidazole anthelmintic agents
GB9205368D0 (en) * 1992-03-12 1992-04-22 Pfizer Ltd Benzimidozole anthelmintic agents
US5278181A (en) * 1992-05-12 1994-01-11 Board Of Regents Acting On Behalf Of The University Of Michigan Soluble alkyl[5-[amino (phenyl)methyl]-1H-benzimidazol-2-yl] carbamate anthelmintics

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657267A (en) 1969-06-20 1972-04-18 Janssen Pharmaceutica Nv Benzimidazole carbamates
BE787412A (fr) 1971-08-14 1973-02-12 Bayer Ag Nouveaux derives d'acides aminobenzimidazole-carboxyliques leurprocede de preparation et leur application comme fongicides systemiques et bactericides
DE2541752A1 (de) * 1975-09-19 1977-03-24 Hoechst Ag Anthelminthisch wirksame 2-carbalkoxyamino-5(6)-phenyl-sulfonyloxy- benzimidazole und verfahren zu ihrer herstellung
PT65486B (en) * 1975-08-28 1978-03-24 Lilly Co Eli Process for the preparation of carbonil-substituted 1-sulfonylbenzimidazoles
US4230868A (en) 1979-04-17 1980-10-28 Eli Lilly And Company α-Alkyl-α-hydroxybenzyl-substituted 1-sulfonylbenzimidazoles
IL68297A (en) * 1982-04-08 1986-09-30 Lilly Co Eli Process for removing 1-sulfonyl groups from 2-amino-5(6)-substituted benzimidazoles
US4434288A (en) * 1982-04-08 1984-02-28 Eli Lilly And Company Preparation of substituted 1-thiazinyl or 1-thiazolyl-2-aminobenzimidazoles

Also Published As

Publication number Publication date
US4435418A (en) 1984-03-06
ATE30323T1 (de) 1987-11-15
ZA838262B (en) 1984-06-27
PT77738A (en) 1983-12-01
FI834550A7 (fi) 1984-06-14
NO834566L (no) 1984-06-14
EG16161A (en) 1986-12-30
ZW23983A1 (en) 1984-02-08
NZ206124A (en) 1986-09-10
AU561969B2 (en) 1987-05-21
EP0112133A1 (en) 1984-06-27
EP0112133B1 (en) 1987-10-21
IL70125A (en) 1987-12-31
DK552883A (da) 1984-06-14
ES527947A0 (es) 1985-09-16
FI834550A0 (fi) 1983-12-12
DE3374124D1 (de) 1987-11-26
NO159380C (no) 1988-12-21
KR840006976A (ko) 1984-12-04
GR79743B (es) 1984-10-31
AU2222483A (en) 1984-06-21
CA1199924A (en) 1986-01-28
PT77738B (en) 1986-03-27
IL70125A0 (en) 1984-02-29
DK552883D0 (da) 1983-12-01
NO159380B (no) 1988-09-12
PH18341A (en) 1985-06-05
FI834550L (fi) 1984-06-14
JPS59116275A (ja) 1984-07-05

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