ES8600767A1 - Un procedimiento para la preparacion de derivados de 7-oxo-1-azabiciclo (3.2.0) hepteno - Google Patents
Un procedimiento para la preparacion de derivados de 7-oxo-1-azabiciclo (3.2.0) heptenoInfo
- Publication number
- ES8600767A1 ES8600767A1 ES525588A ES525588A ES8600767A1 ES 8600767 A1 ES8600767 A1 ES 8600767A1 ES 525588 A ES525588 A ES 525588A ES 525588 A ES525588 A ES 525588A ES 8600767 A1 ES8600767 A1 ES 8600767A1
- Authority
- ES
- Spain
- Prior art keywords
- compound
- preparation
- formula
- carbapenem compound
- co2ch2ch2x
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 carbapenem compound Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- YIFHJRQMDVEJGF-XOTABTKWSA-N (5r,6s)-3-[(z)-3-(2-aminoethoxy)-3-oxoprop-1-enyl]sulfanyl-6-[(1r)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid Chemical compound C1C(S\C=C/C(=O)OCCN)=C(C(O)=O)N2C(=O)[C@H]([C@H](O)C)[C@H]21 YIFHJRQMDVEJGF-XOTABTKWSA-N 0.000 abstract 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000002243 precursor Chemical group 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003573 thiols Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE 7-OXO-1-AZABIBICLO (3.2.0) HEPTENO, DE FORMULA GENERAL (I), ES DECIR, ACIDO (5R,6S)-3-2-(Z)-(2-AMINOETOXICARBONIL)ETENILTIO-6-(R)-1-HIDROXIETIL-7-OXO-1-AZABICICLO3.2.0HEPT-2-EN-2-CARBOXILICO.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III) O CON UN DERIVADO REACTIVO DEL MISMO.DE APLICACION EN EL TRATAMIENTO DE LAS INFECCIONES BACTERIANAS EN LOS ANIMALES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8133769 | 1981-11-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES525588A0 ES525588A0 (es) | 1985-02-16 |
| ES8600767A1 true ES8600767A1 (es) | 1985-02-16 |
Family
ID=10525739
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES517225A Granted ES517225A0 (es) | 1981-11-09 | 1982-11-08 | Un procedimiento para la preparacion de derivados de 7-oxo-1-azabiciclo (3,2-0) hepteno. |
| ES525588A Expired ES8600767A1 (es) | 1981-11-09 | 1983-09-13 | Un procedimiento para la preparacion de derivados de 7-oxo-1-azabiciclo (3.2.0) hepteno |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES517225A Granted ES517225A0 (es) | 1981-11-09 | 1982-11-08 | Un procedimiento para la preparacion de derivados de 7-oxo-1-azabiciclo (3,2-0) hepteno. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0079167A1 (es) |
| JP (1) | JPS5888380A (es) |
| AU (1) | AU9023682A (es) |
| ES (2) | ES517225A0 (es) |
| ZA (1) | ZA828169B (es) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4061378A (en) * | 1977-10-19 | 1980-04-17 | Merck & Co., Inc. | 1-azabicyclo (3.2.0) hept-2-enes |
| EP0024832B1 (en) * | 1979-08-10 | 1985-03-13 | Beecham Group Plc | Beta-lactam antibiotics, their preparation, pharmaceutical compositions containing them and their preparation |
-
1982
- 1982-10-27 EP EP82305687A patent/EP0079167A1/en not_active Withdrawn
- 1982-11-08 ZA ZA828169A patent/ZA828169B/xx unknown
- 1982-11-08 ES ES517225A patent/ES517225A0/es active Granted
- 1982-11-08 AU AU90236/82A patent/AU9023682A/en not_active Abandoned
- 1982-11-09 JP JP57197421A patent/JPS5888380A/ja active Pending
-
1983
- 1983-09-13 ES ES525588A patent/ES8600767A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ZA828169B (en) | 1983-07-27 |
| EP0079167A1 (en) | 1983-05-18 |
| JPS5888380A (ja) | 1983-05-26 |
| ES8402302A1 (es) | 1984-02-01 |
| ES517225A0 (es) | 1984-02-01 |
| ES525588A0 (es) | 1985-02-16 |
| AU9023682A (en) | 1983-05-19 |
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