ES8600928A1 - Un metodo de producir un preparado de nifedipina particularmente adecuado para administracion rectal - Google Patents
Un metodo de producir un preparado de nifedipina particularmente adecuado para administracion rectalInfo
- Publication number
- ES8600928A1 ES8600928A1 ES537705A ES537705A ES8600928A1 ES 8600928 A1 ES8600928 A1 ES 8600928A1 ES 537705 A ES537705 A ES 537705A ES 537705 A ES537705 A ES 537705A ES 8600928 A1 ES8600928 A1 ES 8600928A1
- Authority
- ES
- Spain
- Prior art keywords
- production
- nifedipine
- nifedipine compositions
- compositions
- effect
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- HYIMSNHJOBLJNT-UHFFFAOYSA-N nifedipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1[N+]([O-])=O HYIMSNHJOBLJNT-UHFFFAOYSA-N 0.000 title abstract 2
- 229960001597 nifedipine Drugs 0.000 title abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 230000010339 dilation Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/15—Suppositories
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE UN PREPARADO DE NIFEDIPINA PARTICULARMENTE ADECUADO PARA LA ADMINISTRACION RECTAL EN EL QUE LA NIFEDIPINA ESTA CONTENIDA EN UNA BASE FORMADA POR 5 A 50 PARTES EN PESO DE POLIALQUILENGLICOL Y POR 95 A 50 PARTES EN PESO DE GRASA Y ACEITE. CONSISTE EN MEZCLAR LA NIFEDIPINA CON UNA MEZCLA CALIENTE Y FUNDIDA DE POLIALQUILENGLICOL GRASA Y ACEITE Y A CONTINUACION DICHA MEZCLA HOMOGENEIZADA SE VIERTE EN UN MOLDE ADECUADO O SIMILAR TAL COMO UNA PIEZA VACIADA O UN ENVASE. DE APLICACION COMO PRODUCTO FARMACEUTICO UTILIZADO EN LA TERAPIA DE LA ANGINA DE PECHO E HIPERTENSION.-
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58217396A JPS60109519A (ja) | 1983-11-17 | 1983-11-17 | ニフェジピン坐剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES537705A0 ES537705A0 (es) | 1985-10-16 |
| ES8600928A1 true ES8600928A1 (es) | 1985-10-16 |
Family
ID=16703529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES537705A Expired ES8600928A1 (es) | 1983-11-17 | 1984-11-16 | Un metodo de producir un preparado de nifedipina particularmente adecuado para administracion rectal |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4874774A (es) |
| JP (1) | JPS60109519A (es) |
| KR (1) | KR920001459B1 (es) |
| CA (1) | CA1238279A (es) |
| CH (1) | CH661436A5 (es) |
| DE (1) | DE3442065C2 (es) |
| ES (1) | ES8600928A1 (es) |
| FR (1) | FR2555048B1 (es) |
| GB (1) | GB2149662B (es) |
| IT (1) | IT1178239B (es) |
| NL (1) | NL8403310A (es) |
| SE (1) | SE464742B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2736269B2 (ja) * | 1989-07-20 | 1998-04-02 | 日清製粉株式会社 | 1,4−ジヒドロピリジン医薬組成物 |
| US5145859A (en) * | 1991-03-20 | 1992-09-08 | Case Western Reserve University | Methods of treating interstitial cystitis and urethral syndrome |
| JP3467628B2 (ja) * | 1991-05-24 | 2003-11-17 | 岩城製薬株式会社 | 坐剤用基剤 |
| AU733047C (en) | 1997-02-24 | 2002-05-16 | S.L.A. Pharma Ag | Pharmaceutical composition |
| US6537504B1 (en) | 1998-04-06 | 2003-03-25 | Li Young | Method and apparatus for concurrent and sequential multi-step reactions for producing a plurality of different chemical compounds |
| DE19949897A1 (de) * | 1999-10-15 | 2001-04-19 | Rainer Rogasch | Formkörper und Verfahren zu dessen Herstellung |
| RU2177781C1 (ru) * | 2000-12-06 | 2002-01-10 | Научный Центр Здоровья детей РАМН | Суппозитории ректальные, содержащие витаминный комплекс |
| ITMI20020756A1 (it) * | 2002-04-09 | 2003-10-09 | Sinclair Pharma S R L | Composizioni farmaceutiche topiche per il trattamento delle dermatiti |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2538127A (en) * | 1948-02-26 | 1951-01-16 | Searle & Co | Medicated suppositories and bases therefor |
| DE1670827C3 (de) * | 1967-03-20 | 1974-10-24 | Bayer Ag, 5090 Leverkusen | 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin |
| JPS6030650B2 (ja) * | 1979-10-26 | 1985-07-17 | 日本油脂株式会社 | 座薬基剤組成物 |
| JPS56115726A (en) * | 1980-02-20 | 1981-09-11 | Kaken Pharmaceut Co Ltd | Pharmaceutical containing nifedipine |
| DE3021958A1 (de) * | 1980-06-12 | 1981-12-24 | Bayer Ag, 5090 Leverkusen | 1,4-dihydropyridine, verfahren zu deren herstellung sowie diese enthaltende arzneimittel |
| JPS5758609A (en) * | 1980-09-26 | 1982-04-08 | Kaken Pharmaceut Co Ltd | Drug containing nifedipine |
| DE3241263A1 (de) * | 1982-11-09 | 1984-05-10 | Troponwerke GmbH & Co KG, 5000 Köln | Indometacin enthaltende rektale zubereitungen |
-
1983
- 1983-11-17 JP JP58217396A patent/JPS60109519A/ja active Granted
-
1984
- 1984-10-19 GB GB08426420A patent/GB2149662B/en not_active Expired
- 1984-10-31 NL NL8403310A patent/NL8403310A/nl not_active Application Discontinuation
- 1984-11-13 CH CH5421/84A patent/CH661436A5/fr not_active IP Right Cessation
- 1984-11-15 CA CA000467925A patent/CA1238279A/en not_active Expired
- 1984-11-15 SE SE8405731A patent/SE464742B/sv not_active IP Right Cessation
- 1984-11-15 KR KR1019840007171A patent/KR920001459B1/ko not_active Expired
- 1984-11-15 FR FR8417435A patent/FR2555048B1/fr not_active Expired
- 1984-11-15 IT IT49172/84A patent/IT1178239B/it active
- 1984-11-16 ES ES537705A patent/ES8600928A1/es not_active Expired
- 1984-11-17 DE DE3442065A patent/DE3442065C2/de not_active Expired - Fee Related
-
1986
- 1986-08-12 US US06/895,806 patent/US4874774A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE3442065A1 (de) | 1985-05-30 |
| SE464742B (sv) | 1991-06-10 |
| GB2149662A (en) | 1985-06-19 |
| GB2149662B (en) | 1987-06-10 |
| ES537705A0 (es) | 1985-10-16 |
| SE8405731L (sv) | 1985-05-18 |
| FR2555048B1 (fr) | 1988-04-15 |
| NL8403310A (nl) | 1985-06-17 |
| CA1238279A (en) | 1988-06-21 |
| DE3442065C2 (de) | 1994-05-05 |
| KR850003501A (ko) | 1985-06-20 |
| SE8405731D0 (sv) | 1984-11-15 |
| IT8449172A1 (it) | 1986-05-15 |
| KR920001459B1 (ko) | 1992-02-14 |
| US4874774A (en) | 1989-10-17 |
| JPH048410B2 (es) | 1992-02-17 |
| GB8426420D0 (en) | 1984-11-28 |
| IT8449172A0 (it) | 1984-11-15 |
| FR2555048A1 (fr) | 1985-05-24 |
| CH661436A5 (fr) | 1987-07-31 |
| IT1178239B (it) | 1987-09-09 |
| JPS60109519A (ja) | 1985-06-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970401 |