ES8601295A1 - Procedimiento para preparar de halofenilgliceridos. - Google Patents

Procedimiento para preparar de halofenilgliceridos.

Info

Publication number
ES8601295A1
ES8601295A1 ES530745A ES530745A ES8601295A1 ES 8601295 A1 ES8601295 A1 ES 8601295A1 ES 530745 A ES530745 A ES 530745A ES 530745 A ES530745 A ES 530745A ES 8601295 A1 ES8601295 A1 ES 8601295A1
Authority
ES
Spain
Prior art keywords
general formula
chlorine
halogenophenyl
glyceride esters
glyceride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530745A
Other languages
English (en)
Other versions
ES530745A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca SAS
Imperial Chemical Industries Ltd
Original Assignee
ICI Pharma SA
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ICI Pharma SA, Imperial Chemical Industries Ltd filed Critical ICI Pharma SA
Publication of ES530745A0 publication Critical patent/ES530745A0/es
Publication of ES8601295A1 publication Critical patent/ES8601295A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE ESTERES DE HALOFENILGLICERIDOS DE FORMULA GENERAL (I) EN LA QUE RA Y RB SON INDEPENDIENTEMENTE ALQUILO C3-15; RC ES CLORO; RD Y RE SON CLORO OBROMO; Y A ES ALQUILENO C2-4 OPCIONALMENTE PORTANDO UNO O DOS SUSTITUYENTES METILO. CONSISTE EN HACER REACCIONAR UN FENOL DE FORMULA GENERAL (II) CON UN DERIVADO REACTIVO DE UN DIACIDO DE FORMULA GENERAL: HO2C.A.CO2H Y UN GLICERIDO DE FORMULA GENERAL (III) EN LA QUE RA RB RC RD RE Y A TIENEN LOS SIGNIFICADOS YA MENCIONADOS. DE APLICACION EN LA TERAPIA Y PROFILAXIS TOPICA DEL ACNE VULGARIS Y ESTADOS DE INFECCION DE LA PIEL AFINES.
ES530745A 1982-06-18 1984-03-16 Procedimiento para preparar de halofenilgliceridos. Expired ES8601295A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP82401119 1982-06-18

Publications (2)

Publication Number Publication Date
ES530745A0 ES530745A0 (es) 1985-11-01
ES8601295A1 true ES8601295A1 (es) 1985-11-01

Family

ID=8189916

Family Applications (3)

Application Number Title Priority Date Filing Date
ES523376A Expired ES8500318A1 (es) 1982-06-18 1983-06-17 Esteres de halofenilgliceridos
ES530744A Granted ES530744A0 (es) 1982-06-18 1984-03-16 Procedimiento para preparar esteres de halofenilgliceridos.
ES530745A Expired ES8601295A1 (es) 1982-06-18 1984-03-16 Procedimiento para preparar de halofenilgliceridos.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES523376A Expired ES8500318A1 (es) 1982-06-18 1983-06-17 Esteres de halofenilgliceridos
ES530744A Granted ES530744A0 (es) 1982-06-18 1984-03-16 Procedimiento para preparar esteres de halofenilgliceridos.

Country Status (25)

Country Link
US (1) US4587262A (es)
EP (1) EP0099177B1 (es)
JP (1) JPS5951240A (es)
KR (1) KR840005068A (es)
AT (1) ATE21686T1 (es)
AU (1) AU562207B2 (es)
CA (1) CA1221983A (es)
CS (2) CS241088B2 (es)
DD (1) DD210029A5 (es)
DE (1) DE3365634D1 (es)
DK (1) DK278283D0 (es)
ES (3) ES8500318A1 (es)
FI (1) FI832227A7 (es)
GB (1) GB8313634D0 (es)
GR (1) GR79196B (es)
HU (1) HU191531B (es)
IE (1) IE55531B1 (es)
IL (1) IL68950A (es)
NO (1) NO832203L (es)
NZ (1) NZ204625A (es)
PH (1) PH20587A (es)
PL (1) PL242535A1 (es)
PT (1) PT76889B (es)
ZA (1) ZA834135B (es)
ZW (1) ZW12983A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8313634D0 (en) * 1982-06-18 1983-06-22 Ici Plc Halogenophenyl glyceride esters
US4642366A (en) * 1984-03-05 1987-02-10 Stauffer Chemical Company Process for preparing methyl phosphonamides
JP2001509137A (ja) * 1996-11-12 2001-07-10 タマーキン ファーマシューティカル イノベイション リミテッド 皮膚疾患の治療方法
US6949663B2 (en) 2000-11-10 2005-09-27 Japan Science And Technology Corporation Carboxylic acid-type lipid
FR2839448A1 (fr) * 2002-05-07 2003-11-14 Oreal Utilisation d'esters de triclosan, de piroctone et de tropolone dans une composition a liberation controlee
US8026285B2 (en) 2007-09-04 2011-09-27 Bezwada Biomedical, Llc Control release of biologically active compounds from multi-armed oligomers
US8048980B2 (en) 2007-09-17 2011-11-01 Bezwada Biomedical, Llc Hydrolysable linkers and cross-linkers for absorbable polymers
US8053591B2 (en) 2007-09-26 2011-11-08 Bezwada Biomedical, Llc Functionalized biodegradable triclosan monomers and oligomers for controlled release
CN103857440B (zh) 2011-06-22 2018-09-25 维奥姆生物科学有限公司 基于缀合物的抗真菌和抗细菌前药
CN117088931A (zh) 2014-08-12 2023-11-21 莫纳什大学 定向淋巴的前药
US11738087B2 (en) 2015-09-08 2023-08-29 Monash University Lymph directing prodrugs
CA3077739A1 (en) 2017-08-29 2019-03-07 Puretech Lyt, Inc. Lymphatic system-directing lipid prodrugs
US11883497B2 (en) 2017-08-29 2024-01-30 Puretech Lyt, Inc. Lymphatic system-directing lipid prodrugs
EP4262778A4 (en) * 2020-12-21 2025-10-22 Univ New York State Res Found PENETRATING CRYOPROTECTIVE AGENTS AND METHODS OF MAKING AND USING THE SAME

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3506720A (en) * 1963-02-22 1970-04-14 Geigy Chem Corp Halogenated hydroxy-diphenyl ethers
CH406127A (de) * 1963-02-22 1966-08-15 Geigy Ag J R Verfahren zum antimikrobiellen Ausrüsten von Textilien
NL133434C (es) * 1963-02-22 1972-02-15
GB1051823A (es) * 1964-02-14
FR1441499A (fr) * 1964-02-14 1966-06-10 Geigy Ag J R Nouveaux esters phényliques doués de propriétés antimicrobiennes, utilisables en particulier pour la protection des matériaux organiques
GB8313634D0 (en) * 1982-06-18 1983-06-22 Ici Plc Halogenophenyl glyceride esters

Also Published As

Publication number Publication date
DE3365634D1 (de) 1986-10-02
NO832203L (no) 1983-12-19
ES8505921A1 (es) 1985-06-16
ES530745A0 (es) 1985-11-01
AU562207B2 (en) 1987-06-04
CS394384A2 (en) 1985-07-16
FI832227L (fi) 1983-12-19
FI832227A7 (fi) 1983-12-19
CS445683A2 (en) 1985-07-16
KR840005068A (ko) 1984-11-03
PT76889B (en) 1986-01-24
IL68950A (en) 1988-05-31
HU191531B (en) 1987-03-30
FI832227A0 (fi) 1983-06-17
DK278283D0 (da) 1983-06-16
DD210029A5 (de) 1984-05-30
EP0099177B1 (en) 1986-08-27
GR79196B (es) 1984-10-22
GB8313634D0 (en) 1983-06-22
ES523376A0 (es) 1984-10-01
CS241088B2 (en) 1986-03-13
EP0099177A1 (en) 1984-01-25
IE55531B1 (en) 1990-10-24
ES8500318A1 (es) 1984-10-01
ZA834135B (en) 1984-04-25
PH20587A (en) 1987-02-20
CS241061B2 (en) 1986-03-13
ES530744A0 (es) 1985-06-16
JPS5951240A (ja) 1984-03-24
PT76889A (en) 1983-07-01
ATE21686T1 (de) 1986-09-15
IE831435L (en) 1983-12-18
CA1221983A (en) 1987-05-19
PL242535A1 (en) 1984-09-24
AU1569883A (en) 1985-10-03
ZW12983A1 (en) 1985-01-30
US4587262A (en) 1986-05-06
NZ204625A (en) 1985-10-11

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