ES8604122A1 - Procedimiento de preparacion de eteres oximas basicos y de sus sales de adicion acidas farmaceuticamente aceptables - Google Patents
Procedimiento de preparacion de eteres oximas basicos y de sus sales de adicion acidas farmaceuticamente aceptablesInfo
- Publication number
- ES8604122A1 ES8604122A1 ES544287A ES544287A ES8604122A1 ES 8604122 A1 ES8604122 A1 ES 8604122A1 ES 544287 A ES544287 A ES 544287A ES 544287 A ES544287 A ES 544287A ES 8604122 A1 ES8604122 A1 ES 8604122A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- hal
- diaminoalkoxy
- phenylmethylene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001924 cycloalkanes Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 2
- 208000010513 Stupor Diseases 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 230000003288 anthiarrhythmic effect Effects 0.000 abstract 1
- 239000003416 antiarrhythmic agent Substances 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Anesthesiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE ETERES OXIMAS BASICOS Y DE SUS SALES DE ADICION DE ACIDOS FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE A, R, R1 Y R2 PUEDEN SER VARIOS TIPOS DE RADICALES; Y N VALE 4, 5 O 6. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO HALOGENADO DE FORMUA Y-A-HAL; SEGUIDA DEL TRATAMIENTO DEL COMPUESTO FORMADO CON UNA AMINA DE FORMULA R1NHR2, O UNA SAL DE ADICION DE ACIDO DE LA MISMA; FORMULAS EN LAS QUE HAL ES HALOGENO, X E Y PUEDEN SER VARIOS RADICALES Y LOS DEMAS SIMBOLOS TIENEN LOS MISMOS SIGNIFICADOS QUE EN LA FORMULA (I). ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS EFECTOS POTENCIADORES DE LA NARCOSIS, ANALGESICOS Y ANTIARRITMICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU83414A HU188250B (en) | 1983-02-08 | 1983-02-08 | Process for producing of basical oxim-ethers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES544287A0 ES544287A0 (es) | 1986-01-16 |
| ES8604122A1 true ES8604122A1 (es) | 1986-01-16 |
Family
ID=10949510
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES529565A Expired ES8606258A1 (es) | 1983-02-08 | 1984-02-08 | Procedimiento de preparacion de eteres oximas basicos, y de sus sales de adicion acidas farmaceuticamente aceptables |
| ES544287A Expired ES8604122A1 (es) | 1983-02-08 | 1985-06-17 | Procedimiento de preparacion de eteres oximas basicos y de sus sales de adicion acidas farmaceuticamente aceptables |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES529565A Expired ES8606258A1 (es) | 1983-02-08 | 1984-02-08 | Procedimiento de preparacion de eteres oximas basicos, y de sus sales de adicion acidas farmaceuticamente aceptables |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4727074A (es) |
| JP (1) | JPS59172454A (es) |
| AT (1) | AT389872B (es) |
| AU (1) | AU562028B2 (es) |
| BE (1) | BE898835A (es) |
| CA (1) | CA1247103A (es) |
| CH (1) | CH660004A5 (es) |
| DE (1) | DE3404481A1 (es) |
| DK (1) | DK160299C (es) |
| ES (2) | ES8606258A1 (es) |
| FI (1) | FI78682C (es) |
| FR (1) | FR2540493B1 (es) |
| GB (1) | GB2134904B (es) |
| GR (1) | GR81458B (es) |
| HU (1) | HU188250B (es) |
| IL (1) | IL70885A (es) |
| NL (1) | NL8400376A (es) |
| PH (1) | PH20863A (es) |
| PL (1) | PL141942B1 (es) |
| SE (1) | SE465675B (es) |
| SU (1) | SU1353774A1 (es) |
| YU (1) | YU21984A (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU197205B (en) * | 1984-07-10 | 1989-03-28 | Egyt Gyogyszervegyeszeti Gyar | Process for production of medical compositions against angine |
| DE3620166A1 (de) * | 1986-06-14 | 1987-12-17 | Bayer Ag | Verfahren zur herstellung von hydroxybenzaldoxim-o-ethern |
| HU202195B (en) * | 1987-12-31 | 1991-02-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing new substituted styrene derivatives and medical compositions comprising such compounds |
| HUT67314A (en) * | 1993-04-09 | 1995-03-28 | Egyt Gyogyszervegyeszeti Gyar | Process for prepg. new trisubstituted cykloalkane deriv.s and pharmaceutical compn.s contg. them |
| UA65635C2 (uk) * | 1998-09-03 | 2004-04-15 | Н-Гене Кутато Кфт. | НЕНАСИЧЕНІ ПОХІДНІ ГІДРОКСИМОВОЇ КИСЛОТИ, ЩО МАЮТЬ ВЛАСТИВОСТІ ІНГІБІТОРІВ NAD<sup>+</sup>-ADP-РИБОЗИЛТРАНСФЕРАЗИ |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU169298B (es) * | 1974-09-24 | 1976-11-28 | ||
| US4083978A (en) * | 1976-01-27 | 1978-04-11 | Egyt Gyogyszervegyeszeti Gyar | Oxime ethers |
| DK149043C (da) * | 1976-01-27 | 1986-05-26 | Egyt Gyogyszervegyeszeti Gyar | Analogifremgangsmaade til fremstilling af 2-benzal- eller 2-benzyl-1-(aminoalkoxyimino)-cykloalkaner eller salte eller kvaternaere ammoniumderivater deraf |
| HU180739B (en) * | 1979-07-03 | 1983-04-29 | Egyt Gyogyszervegyeszeti Gyar | Process for producing basic oxime-ethers |
-
1983
- 1983-02-08 HU HU83414A patent/HU188250B/hu not_active IP Right Cessation
-
1984
- 1984-02-03 BE BE1/010952A patent/BE898835A/fr not_active IP Right Cessation
- 1984-02-03 PH PH30201A patent/PH20863A/en unknown
- 1984-02-06 AT AT0036984A patent/AT389872B/de not_active IP Right Cessation
- 1984-02-06 CH CH546/84A patent/CH660004A5/de not_active IP Right Cessation
- 1984-02-07 IL IL70885A patent/IL70885A/xx unknown
- 1984-02-07 DK DK054684A patent/DK160299C/da not_active IP Right Cessation
- 1984-02-07 CA CA000446931A patent/CA1247103A/en not_active Expired
- 1984-02-07 SE SE8400629A patent/SE465675B/sv not_active IP Right Cessation
- 1984-02-07 AU AU24248/84A patent/AU562028B2/en not_active Ceased
- 1984-02-07 FI FI840500A patent/FI78682C/fi not_active IP Right Cessation
- 1984-02-07 PL PL1984246099A patent/PL141942B1/pl unknown
- 1984-02-07 YU YU00219/84A patent/YU21984A/xx unknown
- 1984-02-07 NL NL8400376A patent/NL8400376A/nl not_active Application Discontinuation
- 1984-02-07 GB GB08403233A patent/GB2134904B/en not_active Expired
- 1984-02-07 FR FR8401833A patent/FR2540493B1/fr not_active Expired
- 1984-02-08 SU SU843702235A patent/SU1353774A1/ru active
- 1984-02-08 DE DE19843404481 patent/DE3404481A1/de not_active Withdrawn
- 1984-02-08 JP JP59021513A patent/JPS59172454A/ja active Pending
- 1984-02-08 GR GR73746A patent/GR81458B/el unknown
- 1984-02-08 ES ES529565A patent/ES8606258A1/es not_active Expired
- 1984-02-08 US US06/578,286 patent/US4727074A/en not_active Expired - Fee Related
-
1985
- 1985-06-17 ES ES544287A patent/ES8604122A1/es not_active Expired
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970303 |