ES8603191A1 - Un procedimiento para preparar un derivado de mono-sialo-gangliosido - Google Patents

Un procedimiento para preparar un derivado de mono-sialo-gangliosido

Info

Publication number
ES8603191A1
ES8603191A1 ES534494A ES534494A ES8603191A1 ES 8603191 A1 ES8603191 A1 ES 8603191A1 ES 534494 A ES534494 A ES 534494A ES 534494 A ES534494 A ES 534494A ES 8603191 A1 ES8603191 A1 ES 8603191A1
Authority
ES
Spain
Prior art keywords
sialo
mono
preparing
procedure
hours
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES534494A
Other languages
English (en)
Other versions
ES534494A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of ES8603191A1 publication Critical patent/ES8603191A1/es
Publication of ES534494A0 publication Critical patent/ES534494A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

METODO DE PREPARACION DE DERIVADOS DE MONO-SIALO-GANGLIOSIDO. CONSISTE EN LA CONCENTRACION A VACIO, A UNA TEMPERATURA COMPRENDIDA ENTRE 40JC Y 805JC, DURANTE UN PERIODO DE TIEMPO DE 18 HORAS A 240 HORAS, UNA DISOLUCION ACUOSA DE CATIONES CALCIO A UNA CONCENTRACION ENTRE 1 Y 5 MM, Y UN MONOSIALO-GANGLIOSIDO, DE FORMULA (I), EN LA QUE R1, R2 Y R3 PUEDEN SER VARIOS TIPOS DE RADICALES; AJUSTAR EL PH DE LA DISOLUCION ENTRE 2 Y 3; Y, FINALMENTE DIALIZAR LA DISOLUCION Y EVAPORAR EL DISOLVENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE INFECCIONES BACTERIANAS, VIRICAS, PROTOZOARIAS Y FUNGICAS Y DE TUMORES.
ES534494A 1983-07-21 1984-07-20 Un procedimiento para preparar un derivado de mono-sialo-gangliosido Granted ES534494A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48724/83A IT1168205B (it) 1983-07-21 1983-07-21 Derivato di monsialo ganglioside dotato di attivita' antibatterica, antifungina ed antitumorale, composizioni che lo contengono e procedimento per la loro preparazione

Publications (2)

Publication Number Publication Date
ES8603191A1 true ES8603191A1 (es) 1985-12-01
ES534494A0 ES534494A0 (es) 1985-12-01

Family

ID=11268264

Family Applications (1)

Application Number Title Priority Date Filing Date
ES534494A Granted ES534494A0 (es) 1983-07-21 1984-07-20 Un procedimiento para preparar un derivado de mono-sialo-gangliosido

Country Status (9)

Country Link
US (2) US4728641A (es)
EP (1) EP0136438B1 (es)
JP (1) JPS6084296A (es)
AT (1) ATE75480T1 (es)
DE (1) DE3485680D1 (es)
DK (1) DK166828B1 (es)
ES (1) ES534494A0 (es)
HU (1) HU198091B (es)
IT (1) IT1168205B (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH660557A5 (fr) * 1984-10-26 1987-05-15 Nestle Sa Composition anti-bacterienne et procede de preparation de ses constituants actifs.
DK17885D0 (da) * 1985-01-14 1985-01-14 Karlsson Karl Anders Antiviralt middel
JPH0653764B2 (ja) * 1985-07-31 1994-07-20 三井東圧化学株式会社 モノシアロガングリオシドの製造法
ES2058070T3 (es) * 1986-05-09 1994-11-01 Pulverer Gerhard Utilizacion de monosacaridos especificos para la preparacion de un medicamento para impedir metastasis de tumores malignos.
IT1208751B (it) * 1986-06-30 1989-07-10 Fidia Farmaceutici Possibile uso dei gangliosidi esogeni in malattie tumorali come fattore protettivo contro la neurotossicita' da farmaci antitumorali
EP0508493A1 (en) * 1986-08-06 1992-10-14 Mect Corporation Ganglioside related compounds and method of producing the same
IT1212041B (it) * 1987-11-02 1989-11-08 Fidia Farmaceutici Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche
WO1991008747A1 (en) * 1989-12-13 1991-06-27 Glycomed Incorporated Synthetic receptor molecules recognizable by a rotavirus
WO1991008748A1 (en) * 1989-12-13 1991-06-27 Glycomed Incorporated Synthesis of rotavirus receptor saccharides
WO1993002686A1 (en) * 1991-07-31 1993-02-18 The Regents Of The University Of California Gangliosides with immunosuppressive ceramide moieties
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
DE4204907A1 (de) * 1992-02-14 1993-08-19 Reutter Werner Neuartige glykokonjugate mit n-substituierten neuraminsaeuren als mittel zur stimulierung des immunsystems
TW261533B (es) * 1992-07-16 1995-11-01 Kirin Brewery
ATE191916T1 (de) * 1992-10-22 2000-05-15 Kirin Brewery Neues sphingolglycolipid und verwendung davon
US5780441A (en) * 1993-04-15 1998-07-14 Kirin Beer Kabushiki Kaisha Sphingoglycolipid compounds and therapeutic uses thereof
DE19602108A1 (de) * 1996-01-22 1997-07-24 Beiersdorf Ag Gegen Bakterien, Parasiten, Protozoen, Mycota und Viren wirksame Substanzen
US5747476A (en) * 1996-07-17 1998-05-05 Mortar & Pestle Veterinary Pharmacy, Inc. Treatment of equine protozoal myeloencephalitis
DE19643585A1 (de) * 1996-10-22 1998-04-23 Beiersdorf Ag Antiadhäsive Sphingolipide
AU2001285359A1 (en) * 2000-09-01 2002-03-13 Neuronyx, Inc. Novel synthetic gangliosides
US20020072502A1 (en) * 2000-09-01 2002-06-13 Neuronyx, Inc. Novel synthetic gangliosides
US9969980B2 (en) * 2001-09-21 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
EP1367395A1 (de) * 2002-05-02 2003-12-03 B.R.A.H.M.S Aktiengesellschaft Diagnose von Neoplasmen mit Hilfe von anti-Gangliosid-Antikörpern
EP1358910A1 (de) * 2002-05-02 2003-11-05 B.R.A.H.M.S Aktiengesellschaft Verfahren und Mittel zur Prävention, Hemmung und Therapie von Krebserkrankungen
US9969977B2 (en) * 2002-09-20 2018-05-15 Garnet Biotherapeutics Cell populations which co-express CD49c and CD90
CA2518171C (en) 2003-03-06 2013-07-09 Neose Technologies, Inc. Methods and compositions for the enzymatic synthesis of gangliosides
JP4965063B2 (ja) * 2004-05-07 2012-07-04 雪印メグミルク株式会社 口腔内細菌叢改善剤、抗菌剤及び生育促進剤。
AU2005287891C1 (en) 2004-09-23 2009-07-16 Csr Building Products Limited Hybrid ventilator
US8354370B2 (en) * 2007-06-15 2013-01-15 Garnet Biotherapeutics, Inc. Administering a biological composition or compositions isolated from self-renewing colony forming somatic cell growth medium to treat diseases and disorders
US20090239834A1 (en) * 2008-03-21 2009-09-24 Braincells, Inc. Mcc-257 modulation of neurogenesis
DE102010024041A1 (de) * 2010-05-16 2013-04-04 Alfred Kroll Symtomfreiheit der Atemwege

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT295036B (de) * 1968-11-29 1971-12-27 Leikola Erkki E Verfahren zur Herstellung von neuen Produkten tierischen Ursprungs
US4125492A (en) * 1974-05-31 1978-11-14 Pedro Cuatrecasas Affinity chromatography of vibrio cholerae enterotoxin-ganglioside polysaccharide and the biological effects of ganglioside-containing soluble polymers
FR2478104B1 (fr) * 1980-03-17 1986-08-08 Merieux Inst Nouveaux derives de gangliosides, leur preparation et leur application
EP0058665B1 (en) * 1980-05-09 1986-02-26 LEFFLER, Hakon Carbohydrate derivatives for inhibiting bacterial adherence
CH658458A5 (fr) * 1981-12-17 1986-11-14 Lucchini Lab Sa Procede pour l'obtention du lacto-n-norhexaosyl ceramide.

Also Published As

Publication number Publication date
HU198091B (en) 1989-07-28
US4831021A (en) 1989-05-16
DE3485680D1 (de) 1992-06-04
EP0136438A3 (en) 1987-05-13
ES534494A0 (es) 1985-12-01
IT8348724A1 (it) 1985-01-21
HUT35690A (en) 1985-07-29
EP0136438B1 (en) 1992-04-29
IT1168205B (it) 1987-05-20
US4728641A (en) 1988-03-01
DK356984A (da) 1985-01-22
DK166828B1 (da) 1993-07-19
JPS6084296A (ja) 1985-05-13
DK356984D0 (da) 1984-07-20
IT8348724A0 (it) 1983-07-21
ATE75480T1 (de) 1992-05-15
EP0136438A2 (en) 1985-04-10

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519