ES8604608A1 - Un procedimiento para preparar una sustancia antibiotica seleccionada del antibiotico l 17054 y sus sales por adicion de acidos farmaceuticamente acepatables - Google Patents
Un procedimiento para preparar una sustancia antibiotica seleccionada del antibiotico l 17054 y sus sales por adicion de acidos farmaceuticamente acepatablesInfo
- Publication number
- ES8604608A1 ES8604608A1 ES538606A ES538606A ES8604608A1 ES 8604608 A1 ES8604608 A1 ES 8604608A1 ES 538606 A ES538606 A ES 538606A ES 538606 A ES538606 A ES 538606A ES 8604608 A1 ES8604608 A1 ES 8604608A1
- Authority
- ES
- Spain
- Prior art keywords
- antibiotic
- preparing
- procedure
- pharmaceutically acceptable
- salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/19—Antibiotic
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
UN PROCEDIMIENTO PARA PREPARAR UNA SUSTANCIA ANTIBIOTICA SELECCIONADA DEL ANTIBIOTICO L 17054 Y SUS SALES DE ADICION FARMACEUTICAMENTE ACEPTABLES. CONSISTENTE EN SOMETER UNA PREPARACION EN BRUTO O PURA DEL ANTIBIOTICO TEICOPLANINA, UNO DE SUS FACTORES O DE SUS COMPONENTES O UNA MEZCLA DE LOS FACTORES O COMPONENTES EN CUALQUIER PROPORCION A UNA REACCION DE HIDROLISIS ACIDA EN UN ACIDO ACUOSO CONCENTRADO Y FUERTE COMO EL ACIDO TRIFLUOROACETICO ACUOSO A UNA CONCENTRACION ENTRE 75% Y 95% Y A UNA TEMPERATURA ENTRE 10 Y 50JC, SEGUIDO SI ES NECESARIO DE PURIFICACION, PARA OBTENER COMPUESTOS DE FORMULA (I). SIENDO: A, H; B ES N-ACETIL-B-D-GLUCOSAMINILO Y Z ES A-D-MANOSILO. SE UTILIZA POR SU ACTIVIDAD ANTIMICROBIANA PRINCIPALMENTE FRENTE A LAS BACTERIAS GRAM-POSITIVAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838333624A GB8333624D0 (en) | 1983-12-16 | 1983-12-16 | Antibiotics l 17054 and l 17392 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8604608A1 true ES8604608A1 (es) | 1986-02-01 |
| ES538606A0 ES538606A0 (es) | 1986-02-01 |
Family
ID=10553427
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES538606A Expired ES8604608A1 (es) | 1983-12-16 | 1984-12-14 | Un procedimiento para preparar una sustancia antibiotica seleccionada del antibiotico l 17054 y sus sales por adicion de acidos farmaceuticamente acepatables |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4594187A (es) |
| EP (1) | EP0146822B1 (es) |
| JP (1) | JPS60146895A (es) |
| KR (1) | KR850004497A (es) |
| AR (1) | AR241597A1 (es) |
| AT (1) | ATE51875T1 (es) |
| AU (1) | AU574408B2 (es) |
| CA (1) | CA1250094A (es) |
| DE (1) | DE3481914D1 (es) |
| DK (1) | DK584484A (es) |
| ES (1) | ES8604608A1 (es) |
| FI (1) | FI86433C (es) |
| GB (1) | GB8333624D0 (es) |
| GR (1) | GR81132B (es) |
| HU (1) | HU194283B (es) |
| IE (1) | IE58043B1 (es) |
| IL (1) | IL73806A (es) |
| NO (1) | NO159094C (es) |
| NZ (1) | NZ210545A (es) |
| PH (1) | PH21126A (es) |
| PT (1) | PT79682B (es) |
| ZA (2) | ZA849392B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8307847D0 (en) * | 1983-03-22 | 1983-04-27 | Lepetit Spa | Antibiotics l 17054 and l 17046 |
| IT1173329B (it) * | 1984-02-21 | 1987-06-24 | Lepetit Spa | Procedimento per la trasformazione quantitativa di teicoplanina a2 fattore 1 in teicoplanina a2 fattore 3 |
| GB8420405D0 (en) * | 1984-08-10 | 1984-09-12 | Lepetit Spa | Preparing antibiotic l 17046 |
| US5185320A (en) * | 1989-04-03 | 1993-02-09 | Gruppo Lepetit S.P.A. | O56 -alkyl derivatives of aglycone and pseudo aglycones of teicoplanin |
| EP0406745B1 (en) * | 1989-07-04 | 1995-01-25 | GRUPPO LEPETIT S.p.A. | Antibiotic GE 2270 factors A1, A2, A3 and H |
| WO1992010516A1 (en) * | 1990-12-05 | 1992-06-25 | Gruppo Lepetit S.P.A. | 38-decarboxy-38-hydroxymethyl derivatives of teicoplanin antibiotics, and a process for preparing them |
| KR20000010589A (ko) | 1996-04-23 | 2000-02-15 | 클라우디오 쿼르타 | 항생제a40926의아미드유도체의개선된화학적제조방법 |
| KR100476818B1 (ko) * | 2002-07-19 | 2005-03-17 | 종근당바이오 주식회사 | 테이코플라닌 에이 투 정제 방법 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1587685A (en) * | 1977-03-09 | 1981-04-08 | Microbial Chem Res Found | Macrolactone derivatives and their production |
| US4486584A (en) * | 1980-07-15 | 1984-12-04 | Eli Lilly And Company | Demethylmacrocin compounds and derivatives thereof |
| FI72346C (fi) * | 1981-01-09 | 1987-05-11 | Pierrel Spa | Saett att framstaella nya halvsyntetiska makrolidantibiotika. |
| US4401660A (en) * | 1981-12-14 | 1983-08-30 | Eli Lilly And Company | Ester derivatives of 5-O-mycaminosyl tylonolide and method of using same |
| RO86375A (ro) * | 1982-03-24 | 1985-03-15 | Eli Lilly And Co,Us | Procedeu pentru prepararea antibioticului a 41030 |
| FI73697C (fi) * | 1982-06-08 | 1987-11-09 | Lepetit Spa | Foerfarande foer framstaellning av individuella faktorer 1, 2, 3, 4 och 5 av teikomysin a2. |
| GB8307847D0 (en) * | 1983-03-22 | 1983-04-27 | Lepetit Spa | Antibiotics l 17054 and l 17046 |
| US4521335A (en) * | 1983-07-13 | 1985-06-04 | Smithkline Beckman Corporation | Aglycone and pseudo-aglycones of the AAD 216 antibiotics |
| IT1173329B (it) * | 1984-02-21 | 1987-06-24 | Lepetit Spa | Procedimento per la trasformazione quantitativa di teicoplanina a2 fattore 1 in teicoplanina a2 fattore 3 |
-
1983
- 1983-12-16 GB GB838333624A patent/GB8333624D0/en active Pending
-
1984
- 1984-11-29 AU AU36015/84A patent/AU574408B2/en not_active Ceased
- 1984-11-30 EP EP84114559A patent/EP0146822B1/en not_active Expired - Lifetime
- 1984-11-30 AT AT84114559T patent/ATE51875T1/de not_active IP Right Cessation
- 1984-11-30 DE DE8484114559T patent/DE3481914D1/de not_active Expired - Lifetime
- 1984-11-30 GR GR81132A patent/GR81132B/el unknown
- 1984-12-03 ZA ZA849392A patent/ZA849392B/xx unknown
- 1984-12-05 PH PH31531A patent/PH21126A/en unknown
- 1984-12-07 DK DK584484A patent/DK584484A/da not_active Application Discontinuation
- 1984-12-10 ZA ZA849580A patent/ZA849580B/xx unknown
- 1984-12-11 US US06/680,460 patent/US4594187A/en not_active Expired - Fee Related
- 1984-12-12 IL IL73806A patent/IL73806A/xx unknown
- 1984-12-13 NO NO845006A patent/NO159094C/no unknown
- 1984-12-13 NZ NZ210545A patent/NZ210545A/en unknown
- 1984-12-14 CA CA000470141A patent/CA1250094A/en not_active Expired
- 1984-12-14 IE IE321784A patent/IE58043B1/en not_active IP Right Cessation
- 1984-12-14 JP JP59263080A patent/JPS60146895A/ja active Pending
- 1984-12-14 PT PT79682A patent/PT79682B/pt not_active IP Right Cessation
- 1984-12-14 FI FI844962A patent/FI86433C/fi not_active IP Right Cessation
- 1984-12-14 HU HU844674A patent/HU194283B/hu not_active IP Right Cessation
- 1984-12-14 ES ES538606A patent/ES8604608A1/es not_active Expired
- 1984-12-14 AR AR84298964A patent/AR241597A1/es active
- 1984-12-15 KR KR1019840007994A patent/KR850004497A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0146822B1 (en) | 1990-04-11 |
| DK584484A (da) | 1985-06-17 |
| EP0146822A2 (en) | 1985-07-03 |
| AU574408B2 (en) | 1988-07-07 |
| FI844962L (fi) | 1985-06-17 |
| FI86433C (fi) | 1992-08-25 |
| PT79682A (en) | 1985-01-01 |
| NO159094C (no) | 1988-11-30 |
| PT79682B (en) | 1986-12-10 |
| HU194283B (en) | 1988-01-28 |
| NO159094B (no) | 1988-08-22 |
| DE3481914D1 (de) | 1990-05-17 |
| AU3601584A (en) | 1985-06-20 |
| GB8333624D0 (en) | 1984-01-25 |
| NZ210545A (en) | 1988-05-30 |
| KR850004497A (ko) | 1985-07-15 |
| FI86433B (fi) | 1992-05-15 |
| IE58043B1 (en) | 1993-06-16 |
| IL73806A (en) | 1988-05-31 |
| GR81132B (en) | 1985-03-12 |
| ZA849392B (en) | 1985-09-25 |
| US4594187A (en) | 1986-06-10 |
| IE843217L (en) | 1985-06-16 |
| DK584484D0 (da) | 1984-12-07 |
| PH21126A (en) | 1987-07-27 |
| HUT36839A (en) | 1985-10-28 |
| FI844962A0 (fi) | 1984-12-14 |
| ZA849580B (en) | 1985-09-25 |
| JPS60146895A (ja) | 1985-08-02 |
| AR241597A1 (es) | 1992-09-30 |
| NO845006L (no) | 1985-06-17 |
| CA1250094A (en) | 1989-02-14 |
| ES538606A0 (es) | 1986-02-01 |
| ATE51875T1 (de) | 1990-04-15 |
| IL73806A0 (en) | 1985-03-31 |
| EP0146822A3 (en) | 1985-08-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970401 |