ES8605581A1 - Procedimiento para la hidrolisis enzimatica de una amida de d-alfa-aminoacido. - Google Patents
Procedimiento para la hidrolisis enzimatica de una amida de d-alfa-aminoacido.Info
- Publication number
- ES8605581A1 ES8605581A1 ES547765A ES547765A ES8605581A1 ES 8605581 A1 ES8605581 A1 ES 8605581A1 ES 547765 A ES547765 A ES 547765A ES 547765 A ES547765 A ES 547765A ES 8605581 A1 ES8605581 A1 ES 8605581A1
- Authority
- ES
- Spain
- Prior art keywords
- alpha
- amino acid
- enzymatic hydrolysis
- procedure
- acid amide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000007650 D alpha amino acids Chemical class 0.000 title abstract 3
- 230000007071 enzymatic hydrolysis Effects 0.000 title abstract 2
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- -1 AMIDE D-ALPHA-AMINO ACID Chemical class 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 241000187561 Rhodococcus erythropolis Species 0.000 abstract 1
- 150000001371 alpha-amino acids Chemical class 0.000 abstract 1
- 235000008206 alpha-amino acids Nutrition 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 239000004009 herbicide Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 238000011084 recovery Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
METODO DE HIDROLISIS ENZIMATICA DE UNA AMINA DE D-ALFA-AMINOACIDO EN EL CORRESPONDIENTE D-ALFA-AMINOACIDO. CONSISTE EN EL TRATAMIENTO DE UNA DISOLUCION ACUOSA DE LA AMIDA D-ALFA-AMINOACIDO CON 3 A 6 ATOMOS DE CARBONO CON UNA PREPARACION QUE CONTIENE AMINOACILAMILASA OBTENIDA A PARTIR DE UN CULTIVO DE RHODOCOCCUS ERYTHROPOLIS O UN MUTANTE DEL MISMO, EN FORMA DE CELULAS HUMEDAS, INMOVILIZADO EN UN PORTADOR ADECUADO; SEGUIDA DE LA RECUPERACION DEL ALFA-AMINOACIDO A PARTIR DEL HIDROLIZADO SIGUIENDO METODOS CONVENCIONALES. LA HIDROLISIS SE LLEVA A CABO EN UN MEDIO DE PH ENTRE 6 Y 10, A UNA TEMPERATURA COMPRENDIDA ENTRE 20JC Y 45JC. ESTOS D-ALFA-AMINOACIDOS TIENEN APLICACIONES COMO INTERMEDIOS EN LA SINTESIS DE PRODUCTOS FARMACEUTICOS Y HERBICIDAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL8403093A NL8403093A (nl) | 1984-10-11 | 1984-10-11 | Werkwijze voor de enzymatische hydrolyse van d-alfa-aminozuuramiden. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES547765A0 ES547765A0 (es) | 1986-03-16 |
| ES8605581A1 true ES8605581A1 (es) | 1986-03-16 |
Family
ID=19844596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES547765A Expired ES8605581A1 (es) | 1984-10-11 | 1985-10-10 | Procedimiento para la hidrolisis enzimatica de una amida de d-alfa-aminoacido. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4705752A (es) |
| EP (1) | EP0179523B1 (es) |
| JP (1) | JPS6196989A (es) |
| AT (1) | ATE51022T1 (es) |
| CA (1) | CA1245590A (es) |
| DE (1) | DE3576522D1 (es) |
| DK (1) | DK461985A (es) |
| ES (1) | ES8605581A1 (es) |
| IL (1) | IL76649A0 (es) |
| NL (1) | NL8403093A (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8618559D0 (en) * | 1986-07-30 | 1986-09-10 | Genetics Int Inc | Rhodococcus bacterium |
| DE3719872A1 (de) * | 1987-06-13 | 1988-12-29 | Basf Ag | Verfahren zur herstellung von d-alanin aus l-chlorpropionsaeure |
| US5252470A (en) * | 1988-03-24 | 1993-10-12 | Kyowa Hakko Kogyo Co., Ltd. | D-amidase and process for producing D-α-alanine and/or L-α-alanineamide |
| CA1336414C (en) * | 1988-03-24 | 1995-07-25 | Hideki Kawasaki | D-amidase and process for producing d--alanine and/or l--alanineamide |
| DE3816063A1 (de) * | 1988-05-06 | 1989-11-23 | Schering Ag | Verfahren zur herstellung von l-aminosaeuren und aminosaeure-amiden |
| EP0383403A1 (en) * | 1989-02-16 | 1990-08-22 | Stamicarbon B.V. | Process for preparation of organic chemicals |
| JP3009421B2 (ja) * | 1990-02-28 | 2000-02-14 | 秀明 山田 | 有機酸の生物学的製造法 |
| US5593871A (en) * | 1990-09-20 | 1997-01-14 | E. I. Du Pont De Nemours And Company | Process for the preparation of enantiometric 2-alkanoic acid amides from nitriles |
| US6133002A (en) | 1997-09-25 | 2000-10-17 | Dsm N.V. | Process for preparing optically active 2-amino-ω-oxoalkanoic acid derivatives |
| JP2002253294A (ja) * | 2001-03-02 | 2002-09-10 | Mitsubishi Gas Chem Co Inc | 光学活性脂肪族アミノ酸アミドの製造法 |
| AT412092B (de) * | 2003-02-27 | 2004-09-27 | Dsm Fine Chem Austria Gmbh | Verfahren zur herstellung chiraler alpha-hydroxycarbonsäuren durch enzymatische hydrolyse von chiralen cyanhydrinen |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU74142A1 (es) * | 1976-01-08 | 1977-07-22 | ||
| US4211840A (en) * | 1977-06-08 | 1980-07-08 | Ajinomoto Company, Incorporated | Method for producing D-α-amino acid |
| CA1215924A (en) * | 1983-07-27 | 1986-12-30 | David W. Bewick | Process for producing optically active aryloxypropionic acids and derivatives thereof useful as herbicides |
| NL8400312A (nl) * | 1984-02-02 | 1985-09-02 | Stamicarbon | Optisch aktief gesubstitueerd boterzuuramide alsmede werkwijze voor de optische scheiding van gesubstitueerd boterzuuramide. |
-
1984
- 1984-10-11 NL NL8403093A patent/NL8403093A/nl not_active Application Discontinuation
-
1985
- 1985-09-25 US US06/779,851 patent/US4705752A/en not_active Expired - Fee Related
- 1985-10-09 DK DK461985A patent/DK461985A/da not_active Application Discontinuation
- 1985-10-09 EP EP85201638A patent/EP0179523B1/en not_active Expired - Lifetime
- 1985-10-09 AT AT85201638T patent/ATE51022T1/de not_active IP Right Cessation
- 1985-10-09 DE DE8585201638T patent/DE3576522D1/de not_active Expired - Lifetime
- 1985-10-09 CA CA000492594A patent/CA1245590A/en not_active Expired
- 1985-10-10 ES ES547765A patent/ES8605581A1/es not_active Expired
- 1985-10-10 IL IL76649A patent/IL76649A0/xx unknown
- 1985-10-11 JP JP60225014A patent/JPS6196989A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ATE51022T1 (de) | 1990-03-15 |
| EP0179523B1 (en) | 1990-03-14 |
| DK461985D0 (da) | 1985-10-09 |
| DE3576522D1 (de) | 1990-04-19 |
| CA1245590A (en) | 1988-11-29 |
| IL76649A0 (en) | 1986-02-28 |
| JPS6196989A (ja) | 1986-05-15 |
| EP0179523A1 (en) | 1986-04-30 |
| ES547765A0 (es) | 1986-03-16 |
| US4705752A (en) | 1987-11-10 |
| DK461985A (da) | 1986-04-12 |
| NL8403093A (nl) | 1986-05-01 |
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