ES8605779A1 - Un procedimiento de preparacion del 2,6-dimetil-5-metoxicar-bonil-4-(2-nitrofenil)-1,4-dihidropiridina-3-carboxilato de isobutilo
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Un procedimiento de preparacion del 2,6-dimetil-5-metoxicar-bonil-4-(2-nitrofenil)-1,4-dihidropiridina-3-carboxilato de isobutilo
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MORA RUEDAS PEDRO
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MORA RUEDAS PEDRO
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Publication of ES549302A0publicationCriticalpatent/ES549302A0/es
PROCEDIMIENTO DE PREPARACION DEL 2,6-DIMETIL-5-METOXICARBONIL-4-(2-NITROFENIL)-1,4-DIHIDROPIRIDINA-3-CARBOXILATO DE ISOBUTILO. COMPRENDE: A) HACER REACCIONAR EL 2-NITROBENALDEHIDO CON EL ACETILACETATO DE METILO EN PRESENCIA DE ACETATO DE PIPERIDINA, CATALIZADA POR UNA FUENTE DE ULTRASONIDO DE 50 KHZ A UNA TEMPERATURA DE 20JC, DURANTE 8 HORAS, PARA DAR EL 2-(2-NITROBENCILIDIN)ACETILACETATO DE FORMULA (II); Y B) TRATAR A (II) CON 3-AMINOCROTANATO DE ISOBUTILO DE FORMULA (III), CATALIZADA POR UNA FUENTE DE ULTRASONIDO DE 50 KHZ Y A UNA TEMPERATURA DE 60JC, PARA OBTENER EL 2,6-DIMETIL-5-METOXICARBONIL-4-(2-NITROFENIL)-1,4-DIHIDROPIRIDINA-3-CARBOXILATO DE ISOBULITO DE FORMULA (I).
ES549302A1985-11-261985-11-26Un procedimiento de preparacion del 2,6-dimetil-5-metoxicar-bonil-4-(2-nitrofenil)-1,4-dihidropiridina-3-carboxilato de isobutilo
ExpiredES8605779A1
(es)
Novel imidazo- and triazolothiadiazines, a process for the preparation thereof, medicaments containing same, and the use thereof, and some intermediates formed in the preparation of the compounds mentioned