ATE66454T1 - Herstellung von zwischenverbindungen fuer leukotrienantagonisten. - Google Patents

Herstellung von zwischenverbindungen fuer leukotrienantagonisten.

Info

Publication number: ATE66454T1
Authority: AT; Austria
Prior art keywords: antagonists; leukotrian; production; intermediate compounds; acylbenzenes
Prior art date: 1987-06-19

Application number

AT88305445T

Other languages

English (en)

Inventor

Winston Stanley Marshall

Sandra Kay Sigmund

Celia Ann Whitesitt

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-06-19

Filing date

1988-06-15

Publication date

1991-09-15

1988-06-15 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1991-09-15 Application granted granted Critical

1991-09-15 Publication of ATE66454T1 publication Critical patent/ATE66454T1/de

Links

239000005557 antagonist Substances 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 abstract 2
GHMLBKRAJCXXBS-UHFFFAOYSA-N resorcinol Chemical compound OC1=CC=CC(O)=C1 GHMLBKRAJCXXBS-UHFFFAOYSA-N 0.000 abstract 2
BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical compound NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
239000003199 leukotriene receptor blocking agent Substances 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
235000019260 propionic acid Nutrition 0.000 abstract 1
IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/257—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings
- C07C43/295—Ethers having an ether-oxygen atom bound to carbon atoms both belonging to six-membered aromatic rings containing hydroxy or O-metal groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
- C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pulmonology (AREA)
Immunology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT88305445T 1987-06-19 1988-06-15 Herstellung von zwischenverbindungen fuer leukotrienantagonisten. ATE66454T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US6489787A	1987-06-19	1987-06-19
EP88305445A EP0295883B1 (de)	1987-06-19	1988-06-15	Herstellung von Zwischenverbindungen für Leukotrienantagonisten

Publications (1)

Publication Number	Publication Date
ATE66454T1 true ATE66454T1 (de)	1991-09-15

Family

ID=22058947

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT88305445T ATE66454T1 (de)	1987-06-19	1988-06-15	Herstellung von zwischenverbindungen fuer leukotrienantagonisten.

Country Status (10)

Country	Link
EP (1)	EP0295883B1 (de)
JP (1)	JPS6416741A (de)
KR (1)	KR890000389A (de)
AT (1)	ATE66454T1 (de)
CA (1)	CA1300169C (de)
DE (1)	DE3864325D1 (de)
ES (1)	ES2029883T3 (de)
GR (1)	GR3002591T3 (de)
HU (1)	HU200582B (de)
IL (1)	IL86747A (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0314531D0 (en) *	2003-03-11	2003-07-30	Unilever Plc	Process for the preparation of a cosmetic active
EP1961727A1 (de) *	2007-02-26	2008-08-27	Bayer CropScience AG	Verfahren zur Herstellung von 2,4-Dihydroxyphenyl-4-methoxybenzyl-ketonen
JP2008266374A (ja) *	2007-04-17	2008-11-06	Daicel Chem Ind Ltd	多糖アシレートの製造方法、及び高純度多糖アシレート

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0167286A1 (de) *	1984-06-04	1986-01-08	Celanese Corporation	Verfahren zur Herstellung von 4-Hydroxyacetophenon

1988
- 1988-06-15 AT AT88305445T patent/ATE66454T1/de not_active IP Right Cessation
- 1988-06-15 IL IL86747A patent/IL86747A/xx unknown
- 1988-06-15 CA CA000569500A patent/CA1300169C/en not_active Expired - Lifetime
- 1988-06-15 DE DE8888305445T patent/DE3864325D1/de not_active Expired - Lifetime
- 1988-06-15 EP EP88305445A patent/EP0295883B1/de not_active Expired - Lifetime
- 1988-06-15 ES ES198888305445T patent/ES2029883T3/es not_active Expired - Lifetime
- 1988-06-16 KR KR1019880007200A patent/KR890000389A/ko not_active Ceased
- 1988-06-16 HU HU883093A patent/HU200582B/hu not_active IP Right Cessation
- 1988-06-17 JP JP63151066A patent/JPS6416741A/ja active Pending
1991
- 1991-08-22 GR GR91401189T patent/GR3002591T3/el unknown

Also Published As

Publication number	Publication date
DE3864325D1 (de)	1991-09-26
EP0295883A1 (de)	1988-12-21
GR3002591T3 (en)	1993-01-25
EP0295883B1 (de)	1991-08-21
ES2029883T3 (es)	1992-10-01
IL86747A (en)	1992-06-21
CA1300169C (en)	1992-05-05
IL86747A0 (en)	1988-11-30
HU200582B (en)	1990-07-28
KR890000389A (ko)	1989-03-14
HUT47518A (en)	1989-03-28
JPS6416741A (en)	1989-01-20

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Legal Events

Date	Code	Title	Description
1992-05-15	UEP	Publication of translation of european patent specification
1995-03-15	REN	Ceased due to non-payment of the annual fee