ES8607013A3 - Procedimiento de preparacion de acidos 1-bencil-1h-indazol -3-carboxilicos sustituidos y sus derivados - Google Patents
Procedimiento de preparacion de acidos 1-bencil-1h-indazol -3-carboxilicos sustituidos y sus derivadosInfo
- Publication number
- ES8607013A3 ES8607013A3 ES545644A ES545644A ES8607013A3 ES 8607013 A3 ES8607013 A3 ES 8607013A3 ES 545644 A ES545644 A ES 545644A ES 545644 A ES545644 A ES 545644A ES 8607013 A3 ES8607013 A3 ES 8607013A3
- Authority
- ES
- Spain
- Prior art keywords
- substd
- carboxylic acids
- prepn
- benzyl
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NYVSLTQAYNTLBZ-UHFFFAOYSA-N 4-benzyl-1h-indazole-3-carboxylic acid Chemical class C=12C(C(=O)O)=NNC2=CC=CC=1CC1=CC=CC=C1 NYVSLTQAYNTLBZ-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- 150000001408 amides Chemical class 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- XWJHQOWAYSWCRY-UHFFFAOYSA-N 1-benzylindazole Chemical compound N1=CC2=CC=CC=C2N1CC1=CC=CC=C1 XWJHQOWAYSWCRY-UHFFFAOYSA-N 0.000 abstract 1
- BAXOFTOLAUCFNW-UHFFFAOYSA-N 1H-indazole Chemical compound C1=CC=C2C=NNC2=C1 BAXOFTOLAUCFNW-UHFFFAOYSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE ACIDOS 1-BENCIL-1H-INDAZOL-3-CARBOXILICO SUSTITUIDOS Y SUS DERIVADOS. COMPRENDE: A) HACER REACCIONAR UN INDAZOL DE FORMULA (II) CON UN BENCIL DERIVADO DE FORMULA (III) PARA OBTENER ACIDOS 1-BENCIL-1H-INDAZOL-3-CARBOXILICOS SUSTITUIDOS Y SUS DERIVADOS DE FORMULA (I); B) CUANDO SE USA UN CIANO DERIVADO DE FORMULA (II), HIDROLIZAR EL PRODUCTO DE ACIDO, ESTER O AMIDA; C) CONVERTIR LOS ESTERES EN ACIDOS O AMIDAS, LOS ACIDOS EN ESTERES O AMIDAS, O LAS AMIDAS EN ACIDOS; Y D) FORMAR LA SAL FARMACEUTICAMENTE ACEPTABLE. SIENDO: R, CL O CH3; Y X, UN HAL O UN GRUPO SALIENTE DE REACTIVIDAD SIMILAR. SE UTILIZA PARA LA TERAPIA DE ALGUNOS TUMORES DEL TESTICULO, TAMBIEN COMO ANTIESPERMATOGENICOS EN MEDICINA HUMANA Y VETERINARIA.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES545644A ES545644A0 (es) | 1985-07-29 | 1985-07-29 | Procedimiento de preparacion de acidos 1-bencil-1h-indazol -3-carboxilicos sustituidos y sus derivados |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES545644A ES545644A0 (es) | 1985-07-29 | 1985-07-29 | Procedimiento de preparacion de acidos 1-bencil-1h-indazol -3-carboxilicos sustituidos y sus derivados |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8607013A3 true ES8607013A3 (es) | 1986-06-01 |
| ES545644A0 ES545644A0 (es) | 1986-06-01 |
Family
ID=8489616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES545644A Granted ES545644A0 (es) | 1985-07-29 | 1985-07-29 | Procedimiento de preparacion de acidos 1-bencil-1h-indazol -3-carboxilicos sustituidos y sus derivados |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES545644A0 (es) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101759644B (zh) * | 2005-08-17 | 2011-11-02 | 杭州民生药业有限公司 | 氯尼达明的结晶形式iii、其制备方法和含有所述结晶形式iii的组合物 |
| CN101735151B (zh) * | 2005-08-17 | 2012-07-04 | 杭州民生药业有限公司 | 氯尼达明的结晶形式i、其制备方法和含有所述结晶形式i的组合物 |
-
1985
- 1985-07-29 ES ES545644A patent/ES545644A0/es active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101759644B (zh) * | 2005-08-17 | 2011-11-02 | 杭州民生药业有限公司 | 氯尼达明的结晶形式iii、其制备方法和含有所述结晶形式iii的组合物 |
| CN101735151B (zh) * | 2005-08-17 | 2012-07-04 | 杭州民生药业有限公司 | 氯尼达明的结晶形式i、其制备方法和含有所述结晶形式i的组合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| ES545644A0 (es) | 1986-06-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK128380A (da) | 4-amino-3-quinolin-carboxylsyrer og syreestere deres fremstilling og anvendelse | |
| PT76937A (en) | Process for the preparation of piperidyl esters and/or n-piperydilamides of substituted benzoic acids or dicarbocyclic or heterocyclic carboxylic acids | |
| NL6912790A (en) | 2,2-Di-methyl-omega-aryloxyalkane acids, salts and esters | |
| DE3064657D1 (en) | Process for the co-production of carboxylic acids and carboxylic acid esters | |
| JPS57108073A (en) | N-substituted omega-(2-oxo-4-imidazoline- 1-yl)alkanoic acid compound | |
| MY103573A (en) | Preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains. | |
| IT7922253A0 (it) | Procedimento per fabbricare ammidi di acidi carbossilici alfa, beta-insature, n-sostituite. | |
| IT7967146A0 (it) | Procedimento per la preparazione delle ammidi di acidi carbossilici insaturi | |
| ES2006881A6 (es) | Procedimiento de preparar nuevos derivados anhidrido de acido quinolincarboxilicoacido borico. | |
| ES469496A1 (es) | Procedimiento para preparar acidos y esteres 2-ariloxi-2-( para-fenoxialcoxi)fenilaceticos sustituidos | |
| JPS57109754A (en) | N-benzoyl-omega-anilinoalkane carboxylic acid compound | |
| ES8106276A1 (es) | Un procedimiento para la preparacion de amidas del acido po-liprenilcarboxilico | |
| ES8607013A3 (es) | Procedimiento de preparacion de acidos 1-bencil-1h-indazol -3-carboxilicos sustituidos y sus derivados | |
| DE3263882D1 (en) | 11-deoxoglycyrrhetinic acid hydrogen maleate, process for its production, and its use as a medicine | |
| GB1230630A (es) | ||
| DE3264945D1 (en) | Process for the co-production of carboxylic acids and carboxylic acid esters | |
| DE3070179D1 (en) | A process for the production of 1,4-dihydro-4-oxo-quinoline-2-carboxylic acids, or salts, esters or amides thereof and intermediates therefor | |
| IT8121486A0 (it) | Procedimento per la produzione di ammidi di acidi carbossilici. | |
| AU2014388A (en) | Fluorobenzyl esters of cyclopropane carboxylic acids useful as insecticides | |
| ATE15654T1 (de) | Ester von 2,2-dimethyl-3-formyl-1cyclopropancarbons|ure. | |
| GB1538479A (en) | Imidazobenzoxazines | |
| DE3267033D1 (en) | Process for the co-production of carboxylic acids and carboxylic acid esters | |
| HU9300423D0 (en) | Method for producing amino-methane-phosphonic acid and amino-methane-phosphinic one | |
| NO166122C (no) | Fremgangsmaate for fremstilling av en blanding av 1,1,2,2-tetrahydroperfluoralkanoler og deres estere. | |
| GB1521440A (en) | Method of producing phosphinico substituted aliphatic carboxylic acids |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD2A | Announcement of lapse in spain |
Effective date: 20170627 |