ES8608520A1 - Un procedimiento para preparar derivados de 3-aminopirazolo-(3,4-d)-pirimidina - Google Patents
Un procedimiento para preparar derivados de 3-aminopirazolo-(3,4-d)-pirimidinaInfo
- Publication number
- ES8608520A1 ES8608520A1 ES538518A ES538518A ES8608520A1 ES 8608520 A1 ES8608520 A1 ES 8608520A1 ES 538518 A ES538518 A ES 538518A ES 538518 A ES538518 A ES 538518A ES 8608520 A1 ES8608520 A1 ES 8608520A1
- Authority
- ES
- Spain
- Prior art keywords
- aminopyrazolo
- pyrimidine derivatives
- production
- alkyl
- antiinflammatory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- KFVFSHVEAMTYFQ-UHFFFAOYSA-N 2h-pyrazolo[3,4-d]pyrimidin-3-amine Chemical class C1=NC=C2C(N)=NNC2=N1 KFVFSHVEAMTYFQ-UHFFFAOYSA-N 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 229940125716 antipyretic agent Drugs 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000003226 pyrazolyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP23700083A JPS60126285A (ja) | 1983-12-14 | 1983-12-14 | ３−アミノピラゾロ〔３，４−ｄ〕ピリミジン誘導体 |
| JP12568984A JPS615082A (ja) | 1984-06-18 | 1984-06-18 | ３−アミノピラゾロ〔３，４−ｄ〕ピリミジン誘導体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8608520A1 true ES8608520A1 (es) | 1986-06-16 |
| ES538518A0 ES538518A0 (es) | 1986-06-16 |
Family
ID=26462044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES538518A Expired ES8608520A1 (es) | 1983-12-14 | 1984-12-12 | Un procedimiento para preparar derivados de 3-aminopirazolo-(3,4-d)-pirimidina |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4603203A (da) |
| EP (1) | EP0166054B1 (da) |
| KR (1) | KR910006866B1 (da) |
| CA (1) | CA1263386A (da) |
| DE (1) | DE3477783D1 (da) |
| DK (1) | DK165409C (da) |
| ES (1) | ES8608520A1 (da) |
| GR (1) | GR81241B (da) |
| IE (1) | IE58160B1 (da) |
| PT (1) | PT79667B (da) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0237289A3 (en) * | 1986-03-14 | 1988-07-27 | Takeda Chemical Industries, Ltd. | Pyrazolo [3,4-d] pyrimidine derivatives, their production and use |
| US4912104A (en) * | 1987-08-31 | 1990-03-27 | Takeda Chemical Industries, Ltd. | Tricyclic fused pryimidine derivatives, and their use as pharmaceuticals |
| US4885300A (en) * | 1988-03-03 | 1989-12-05 | Ortho Pharmaceutical Corporation | 4-Substituted pyrazolo[3,4-D]pyrimidine derivatives |
| EP0353941A3 (en) * | 1988-08-02 | 1991-05-02 | Takeda Chemical Industries, Ltd. | Medicament for psoriasis containing derivatives of 3-aminopyrazolo [3,4-d]pyrimidine |
| JP3116230B2 (ja) * | 1989-02-15 | 2000-12-11 | 武田薬品工業株式会社 | 三環式縮合ピリミジン誘導体 |
| US5290782A (en) * | 1989-09-01 | 1994-03-01 | Kyowa Hakko Kogyo Co., Ltd. | Xanthine derivatives |
| SE9701398D0 (sv) * | 1997-04-15 | 1997-04-15 | Astra Pharma Prod | Novel compounds |
| EP1713815A4 (en) * | 2004-02-11 | 2009-03-11 | Smithkline Beecham Corp | PTH AGONISTS |
| AU2007256633B2 (en) | 2006-06-06 | 2013-09-12 | Intra-Cellular Therapies, Inc. | Organic compounds |
| ES2588238T3 (es) * | 2007-12-06 | 2016-10-31 | Intra-Cellular Therapies, Inc. | Derivados de pirazolopirimidin-4,6-diona y su uso como producto farmacéutico |
| MX2011005934A (es) | 2008-12-06 | 2011-12-16 | Intra Cellular Therapies Inc | Compuestos organicos. |
| AU2009322899A1 (en) | 2008-12-06 | 2010-06-10 | Intra-Cellular Therapies, Inc. | Organic compounds |
| BRPI0922700A2 (pt) | 2008-12-06 | 2015-08-11 | Intracellular Therapies Inc | Compostos orgânicos |
| EP2434895A4 (en) | 2009-05-13 | 2013-08-07 | Intra Cellular Therapies Inc | ORGANIC CONNECTIONS |
| US9371327B2 (en) | 2010-05-31 | 2016-06-21 | Intra-Cellular Therapies, Inc. | PDE1 inhibitor compounds |
| EP2575817A4 (en) | 2010-05-31 | 2014-01-08 | Intra Cellular Therapies Inc | ORGANIC CONNECTIONS |
| ES2717688T3 (es) | 2013-03-15 | 2019-06-24 | Intra Cellular Therapies Inc | Inhibidores de la PDE1 para uso en el tratamiento y/o prevención de lesiones de SNC, y enfermedades, trastornos o lesiones de SNP |
| US9546175B2 (en) | 2014-08-07 | 2017-01-17 | Intra-Cellular Therapies, Inc. | Organic compounds |
| US10131671B2 (en) | 2014-08-07 | 2018-11-20 | Intra-Cellular Therapies, Inc. | Organic compounds |
| US10285992B2 (en) | 2014-08-07 | 2019-05-14 | Intra-Cellular Therapies, Inc. | Combinations of PDE1 inhibitors and NEP inhibitors and associated methods |
| CA2961212C (en) | 2014-09-17 | 2024-02-06 | Intra-Cellular Therapies, Inc. | Compounds and methods |
| BR112017012007B1 (pt) | 2014-12-06 | 2022-11-01 | Intra-Cellular Therapies, Inc | Compostos orgânicos inibitórios de pde2, composições farmacêuticas compreendendo os ditos compostos e uso dos mesmos no tratamento de um distúrbio mediado por pde2 |
| WO2016090382A1 (en) | 2014-12-06 | 2016-06-09 | Intra-Cellular Therapies, Inc. | Organic compounds |
| US12364695B2 (en) | 2020-06-02 | 2025-07-22 | Intra-Cellular Therapies, Inc. | Methods of treating inflammatory disease |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1567781A (en) * | 1976-05-15 | 1980-05-21 | Fisons Ltd | Pyrazolopyrimidines |
| EP0063381A1 (de) * | 1981-04-22 | 1982-10-27 | Byk Gulden Lomberg Chemische Fabrik GmbH | Neue Pyrazolo(3,4-d)pyrimidine, Verfahren zu deren Herstellung und sie enthaltende Arzneimittel |
-
1984
- 1984-12-05 US US06/678,479 patent/US4603203A/en not_active Expired - Lifetime
- 1984-12-07 DK DK584284A patent/DK165409C/da not_active IP Right Cessation
- 1984-12-11 CA CA000469761A patent/CA1263386A/en not_active Expired
- 1984-12-12 ES ES538518A patent/ES8608520A1/es not_active Expired
- 1984-12-12 GR GR81241A patent/GR81241B/el unknown
- 1984-12-13 PT PT79667A patent/PT79667B/pt not_active IP Right Cessation
- 1984-12-13 EP EP84308690A patent/EP0166054B1/en not_active Expired
- 1984-12-13 DE DE8484308690T patent/DE3477783D1/de not_active Expired
- 1984-12-13 IE IE320784A patent/IE58160B1/en not_active IP Right Cessation
- 1984-12-13 KR KR1019840007920A patent/KR910006866B1/ko not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| PT79667B (en) | 1986-12-10 |
| EP0166054A1 (en) | 1986-01-02 |
| GR81241B (en) | 1985-04-16 |
| DE3477783D1 (en) | 1989-05-24 |
| CA1263386A (en) | 1989-11-28 |
| KR910006866B1 (ko) | 1991-09-09 |
| IE58160B1 (en) | 1993-07-28 |
| KR850004752A (ko) | 1985-07-27 |
| DK584284D0 (da) | 1984-12-07 |
| ES538518A0 (es) | 1986-06-16 |
| DK584284A (da) | 1985-06-15 |
| PT79667A (en) | 1985-01-01 |
| US4603203A (en) | 1986-07-29 |
| DK165409C (da) | 1993-04-05 |
| EP0166054B1 (en) | 1989-04-19 |
| IE843207L (en) | 1985-06-14 |
| DK165409B (da) | 1992-11-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970401 |