ES8708182A1 - Un metodo para preparar una composicion que contiene tetraciclina - Google Patents

Un metodo para preparar una composicion que contiene tetraciclina

Info

Publication number
ES8708182A1
ES8708182A1 ES551701A ES551701A ES8708182A1 ES 8708182 A1 ES8708182 A1 ES 8708182A1 ES 551701 A ES551701 A ES 551701A ES 551701 A ES551701 A ES 551701A ES 8708182 A1 ES8708182 A1 ES 8708182A1
Authority
ES
Spain
Prior art keywords
tetracycline
possessing anti
effective
compositions possessing
antibacterial tetracycline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES551701A
Other languages
English (en)
Other versions
ES551701A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Foundation of the State University of New York
Original Assignee
Research Foundation of the State University of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Foundation of the State University of New York filed Critical Research Foundation of the State University of New York
Publication of ES8708182A1 publication Critical patent/ES8708182A1/es
Publication of ES551701A0 publication Critical patent/ES551701A0/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Fodder In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

METODO PARA PREPARAR UNA COMPOSICION QUE CONTIENE TETRACICLINA. COMPRENDE: A) FORMAR UNA MEZCLA DE DESDIMETILAMINO-TETRACICLINA EFICAZ COMO ANTI-COLAGENSA, CON UN VOLUMEN POLIMERO ADECUADO, NO TENIENDO LA TETRACICLINA ACTIVIDAD ANTIMICROBIANA EFICAZ Y ENCONTRANDOSE EN UNA CANTIDAD DE 5-50 POR CIENTO DE SU DOSIFICACION ESTANDAR COMO AGENTE ANTIMICROBIANO, SIENDO EL VEHICULO POLIMERO UN MATERIAL POLIMERO SINTETICO COMO COPOLIMERO DE ETILENO Y ACETATO DE VINILO, SIENDO CAPAZ DE LIBERAR CONTROLABLEMENTE LA TETRACICLINA INCORPORADA EN EL DURANTE CIERTO PERIODO DE TIEMPO; B) CONFORMAR LA MEZCLA RESULTANTE PARA CONVERTIRLA EN FIBRAS, PELICULAS O PARTICULAS, SIENDO CAPACES DE SER CONFIGURADAS A TEMPERATURA AMBIENTE ADOPTANDO UNA FORMA ADECUADA PARA SU APLICACION DIRECTA A UNA SUPERFICIE O LUGAR. SE UTILIZA PARA PROTEGER LESIONES DE LA PIEL QUE MUESTRAN DESTRUCCION PATOLOGICA DEL COLAGENO.
ES551701A 1985-02-07 1986-02-06 Un metodo para preparar una composicion que contiene tetraciclina Expired ES8708182A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/699,048 US4704383A (en) 1983-12-29 1985-02-07 Non-antibacterial tetracycline compositions possessing anti-collagenolytic properties and methods of preparing and using same

Publications (2)

Publication Number Publication Date
ES8708182A1 true ES8708182A1 (es) 1987-10-01
ES551701A0 ES551701A0 (es) 1987-10-01

Family

ID=24807719

Family Applications (1)

Application Number Title Priority Date Filing Date
ES551701A Expired ES8708182A1 (es) 1985-02-07 1986-02-06 Un metodo para preparar una composicion que contiene tetraciclina

Country Status (12)

Country Link
US (1) US4704383A (es)
EP (1) EP0195906B1 (es)
JP (1) JP2676080B2 (es)
AT (1) ATE81460T1 (es)
AU (1) AU583884B2 (es)
CA (1) CA1297410C (es)
DE (1) DE3686956T2 (es)
DK (1) DK174997B1 (es)
ES (1) ES8708182A1 (es)
GR (1) GR860333B (es)
IE (1) IE58813B1 (es)
ZA (1) ZA86838B (es)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE34656E (en) * 1983-12-29 1994-07-05 The Research Foundation Of State University Of New York Use of tetracycline to enhance bone protein synthesis and/or treatment of bone deficiency
GR861167B (en) * 1985-05-02 1986-09-30 Research Corp Bone targeted inhibitors of carbonic anhydrase
US5308839A (en) * 1989-12-04 1994-05-03 The Research Foundation Of State University Of New York Composition comprising non-steroidal anti-inflammatory agent tenidap and effectively non-antibacterial tetracycline
JP3016587B2 (ja) * 1989-12-04 2000-03-06 ザ・リサーチ・ファンデーション・オブ・ステート・ユニバーシティ・オブ・ニューヨーク 非ステロイド抗炎症剤及びテトラサイクリンの配合
US5045538A (en) * 1990-06-28 1991-09-03 The Research Foundation Of State University Of New York Inhibition of wasting and protein degradation of mammalian muscle by tetracyclines
WO1992012717A2 (en) * 1991-01-15 1992-08-06 A composition containing a tetracycline and use for inhibiting angiogenesis
US5223248A (en) * 1991-02-11 1993-06-29 The Research Foundation Of State University Of New York Non-antibacterial tetracycline compositions possessing antiplaque properties
US5770588A (en) * 1991-02-11 1998-06-23 The Research Foundation Of State University Of New York Non-antibacterial tetracycline compositions of the prevention and treatment of root caries
CA2094874C (en) * 1992-04-27 2003-02-11 Thomas F. Mcnamara Non-antibacterial tetracycline compositons possessing antiplaque properties
US5258371A (en) * 1992-05-29 1993-11-02 Kuraray Co., Ltd. Method to reduce connective tissue destruction
EP1132080A3 (en) * 1992-09-10 2001-10-17 Children's Medical Center Corporation Biodegradable polymer matrices for sustained delivery of local anesthetic agents
US5922340A (en) 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US5700485A (en) * 1992-09-10 1997-12-23 Children's Medical Center Corporation Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid
US5523297A (en) * 1993-03-02 1996-06-04 The Research Foundation Of State University Of New York Inhibition of excessive phospholipase A2 activity and/or production by non-antimicrobial tetracyclines
US6043231A (en) * 1993-03-02 2000-03-28 The Research Foundation Of State Univ. Of New York Inhibition of excessive phospholipase A2 activity and/or production by non-antimicrobial tetracyclines
US6140099A (en) * 1994-05-20 2000-10-31 The Trustees Of The University Of Pennsylvania Method of delaying fetal membrane rupture by inhibiting matrix metalloproteinase-9 activity
US5641636A (en) * 1994-05-20 1997-06-24 University Of Pennsylvania Method of predicting fetal membrane rupture based on matrix metalloproteinase-9 activity
HUP9700322A3 (en) 1995-06-09 2001-03-28 Euro Celtique Sa Formulations and methods for providing prolonged local anesthesia
WO1997049391A1 (en) 1996-06-24 1997-12-31 Euro-Celtique, S.A. Methods for providing safe local anesthesia
US5827840A (en) * 1996-08-01 1998-10-27 The Research Foundation Of State University Of New York Promotion of wound healing by chemically-modified tetracyclines
US6046187A (en) 1996-09-16 2000-04-04 Children's Medical Center Corporation Formulations and methods for providing prolonged local anesthesia
US5773430A (en) * 1997-03-13 1998-06-30 Research Foundation Of State University Of New York Serine proteinase inhibitory activity by hydrophobic tetracycline
JP2908375B2 (ja) * 1997-04-01 1999-06-21 ザ リサーチ ファンデーション オブ ステート ユニバーシティ オブ ニューヨーク 非抗バクテリア性テトラサイクリン組成物
BR9815499A (pt) 1997-07-02 2001-01-02 Euro Celtique Sa Anestesia prolongada nas juntas e nos espacos corporais.
AU8918898A (en) 1997-08-25 1999-03-16 Harold Brem Prevention of adhesions and excessive scar formation using angiogenesis inhibi tors
DK1041991T3 (da) * 1997-12-19 2008-07-28 Univ New York Ikke-antibakterielle tetracycliner til behandling af multipel sklerose
WO1999040926A1 (en) * 1998-02-13 1999-08-19 Nutramax Laboratories, Inc. Agents and methods for protection, treatment and repair of connective tissue
US6277061B1 (en) * 1998-03-31 2001-08-21 The Research Foundation Of State University Of New York Method of inhibiting membrane-type matrix metalloproteinase
IL139231A0 (en) * 1998-05-27 2001-11-25 Euro Celtique Sa Preparations for the application of anti-inflammatory, especially antiseptic, agents and/or agents promoting the healing of wounds to the lower respiratory tract
US6015804A (en) * 1998-09-11 2000-01-18 The Research Foundation Of State University Of New York Method of using tetracycline compounds to enhance interleukin-10 production
US5998390A (en) * 1998-09-28 1999-12-07 The Research Foundation Of State University Of New York Combination of bisphosphonate and tetracycline
US6946453B2 (en) 1998-11-18 2005-09-20 Collagenex Pharmaceuticals, Inc. 4-dedimethylaminotracycline derivatives
US6506740B1 (en) 1998-11-18 2003-01-14 Robert A. Ashley 4-dedimethylaminotetracycline derivatives
US7300667B1 (en) 1999-05-27 2007-11-27 Euro-Celtique, S.A. Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
US6294694B1 (en) 1999-06-04 2001-09-25 Wisconsin Alumni Research Foundation Matrix metalloproteinase inhibitors and method of using same
US6673843B2 (en) * 1999-06-30 2004-01-06 Emory University Curcumin and curcuminoid inhibition of angiogenesis
US20020132798A1 (en) 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
US7211267B2 (en) * 2001-04-05 2007-05-01 Collagenex Pharmaceuticals, Inc. Methods of treating acne
AU2002256092C1 (en) * 2001-04-05 2009-10-15 Collagenex Pharmaceuticals, Inc. Controlled delivery of tetracycline compounds and tetracycline derivatives
JP2004537544A (ja) 2001-07-13 2004-12-16 パラテック ファーマシューティカルズ インコーポレイテッド 標的治療活性を有するテトラサイクリン化合物
US20060194773A1 (en) * 2001-07-13 2006-08-31 Paratek Pharmaceuticals, Inc. Tetracyline compounds having target therapeutic activities
CA2462572C (en) * 2001-10-05 2008-11-18 Tetragenex Pharmaceuticals, Inc. Tetracycline derivatives and methods of use thereof
ES2551708T3 (es) 2002-01-08 2015-11-23 Paratek Pharmaceuticals, Inc. Compuestos de 4-desdimetilamino tetraciclina
US20090011991A1 (en) * 2002-03-08 2009-01-08 Emory University Novel Curcuminoid-Factor VIIA Constructs as Suppressors of Tumor Growth and Angiogenesis
EP1482926A4 (en) 2002-03-08 2006-04-12 Paratek Pharm Innc AMINO METHYL SUBSTITUTED TETRACYCLINE COMPOUNDS
EP1572078A4 (en) * 2002-03-08 2006-08-09 Univ Emory NEW CURCUMINOID FACTOR VIIa CONSTRUCTS AS MEANS OF SUPPRESSING TUMOR GROWTH AND ANGIOGENESIS
WO2003079984A2 (en) 2002-03-21 2003-10-02 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
ATE489081T1 (de) * 2002-03-29 2010-12-15 Univ New York State Res Found Verwendung von nichtantibakteriellen tetrazyklin- analoga und ihren formulierungen für die behandlung von bakteriellen exotoxinen
EA200900540A1 (ru) 2002-07-12 2009-12-30 Пэрэтек Фамэсьютикэлс, Инк. Замещённые соединения тетрациклина, фармацевтическая композиция и способ лечения чувствительного к тетрациклину состояния у субъекта
WO2004054509A2 (en) * 2002-12-13 2004-07-01 The Research Foundation Of State University Of New York Tetracyclines as anti-fungal agents for treatment of ringworm
CA2894736C (en) 2003-04-07 2019-07-16 Supernus Pharmaceuticals, Inc. Once daily formulations of tetracyclines
JP4738333B2 (ja) 2003-07-09 2011-08-03 パラテック ファーマシューティカルズ インコーポレイテッド ９−アミノメチルテトラサイクリン化合物のプロドラッグ
EP1648859B1 (en) 2003-07-09 2013-02-27 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
WO2005046618A2 (en) * 2003-11-06 2005-05-26 Research Foundation Of State University Of New York, The Methods of treating eczema
US7786099B2 (en) * 2004-01-15 2010-08-31 Paratek Pharmaceuticals, Inc. Aromatic a-ring derivatives of tetracycline compounds
WO2006047671A2 (en) 2004-10-25 2006-05-04 Paratek Pharmaceuticals, Inc. 4-aminotetracyclines and methods of use thereof
EP2269991A3 (en) 2004-10-25 2011-09-21 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
BRPI0602372B8 (pt) 2006-05-18 2021-06-22 Einco Biomaterial Ltda processo de preparação de compósitos em base de biocerâmicas e polímeros biodegradáveis e produto derivado
EP2450347B1 (en) 2006-12-21 2015-06-24 Paratek Pharmaceuticals, Inc. Tetracycline derivatives for the treatment of bacterial, viral and parasitic infections
PT2120963T (pt) * 2006-12-21 2018-12-17 Paratek Pharm Innc Compostos tetraciclina substituídos para tratamento de distúrbios inflamatórios da pele
JP2010525069A (ja) * 2007-04-27 2010-07-22 パラテック ファーマシューティカルズ インコーポレイテッド アミノアルキルテトラサイクリン化合物の合成方法および精製方法
BRPI0813990A2 (pt) * 2007-07-06 2011-09-13 Paratek Pharmaceuticals, Inc. métodos para sintetizar compostos de minociclina substituìda
TWI680117B (zh) 2008-05-19 2019-12-21 派洛泰克藥物股份有限公司 四環素化合物之甲苯磺酸鹽及同素異形體
ES2558512T3 (es) 2008-08-08 2016-02-04 Tetraphase Pharmaceuticals, Inc. Compuestos de tetraciclina sustituida con C7-fluoro
WO2010129057A2 (en) 2009-05-08 2010-11-11 Tetraphase Pharmaceuticals, Inc. Tetracycline compounds
HUE037852T2 (hu) 2009-08-28 2018-09-28 Tetraphase Pharmaceuticals Inc Tetraciklin-vegyületek
JP5820462B2 (ja) 2010-03-31 2015-11-24 テトラフェース ファーマシューティカルズ，インコーポレイテッド 多環式テトラサイクリン化合物
EP2852383A4 (en) * 2012-05-21 2016-03-16 Dcb Usa Llc METHODS OF DRUG TEST USING THE ZEBRAFIC MODEL AND COMPOUNDS TESTED THEREIN
SMT201900096T1 (it) 2012-08-31 2019-02-28 Tetraphase Pharmaceuticals Inc Composti di tetracicline
MA46567A (fr) 2016-10-19 2019-08-28 Tetraphase Pharmaceuticals Inc Formes cristallines de l'éravacycline
WO2020097450A1 (en) 2018-11-09 2020-05-14 Tetraphase Pharmaceuticals, Inc. Polymorphic forms of a compound and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB787882A (en) * 1955-01-26 1957-12-18 Lepetit Spa Desdimethylaminotetracyclines and pharmaceutical preparations containing same
US2895880A (en) * 1955-05-13 1959-07-21 Smith Kline French Lab Sustained release pharmaceutical product
GB925282A (en) * 1960-05-04 1963-05-08 Lepetit Spa Fermentation process for the production of demethyltetracycline
US3304227A (en) * 1965-07-15 1967-02-14 Loyal E Loveless Antibiotic-containing animal feed
US3636202A (en) * 1968-02-12 1972-01-18 Lewis A Klein Treatment of rheumatoid arthritis and related diseases
US4371465A (en) * 1981-10-07 1983-02-01 American Home Products Corporation Mammalian collagenase inhibitors
US4454110A (en) * 1982-05-24 1984-06-12 Forsyth Dental Infirmary For Children Self-gelling liquid composition for topical application in the oral cavity

Also Published As

Publication number Publication date
JP2676080B2 (ja) 1997-11-12
CA1297410C (en) 1992-03-17
DE3686956D1 (de) 1992-11-19
DE3686956T2 (de) 1993-05-06
EP0195906A2 (en) 1986-10-01
IE58813B1 (en) 1993-11-17
AU583884B2 (en) 1989-05-11
ATE81460T1 (de) 1992-10-15
GR860333B (en) 1986-06-13
IE860333L (en) 1986-08-07
US4704383A (en) 1987-11-03
DK174997B1 (da) 2004-04-13
DK62286A (da) 1986-08-08
DK62286D0 (da) 1986-02-07
ZA86838B (en) 1986-10-29
ES551701A0 (es) 1987-10-01
JPS61243023A (ja) 1986-10-29
EP0195906B1 (en) 1992-10-14
AU5298486A (en) 1986-08-14
EP0195906A3 (en) 1988-10-19

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20060711