ES8800252A1 - Procedimiento para la obtencion de derivados de hexosa acilados - Google Patents
Procedimiento para la obtencion de derivados de hexosa aciladosInfo
- Publication number
- ES8800252A1 ES8800252A1 ES552144A ES552144A ES8800252A1 ES 8800252 A1 ES8800252 A1 ES 8800252A1 ES 552144 A ES552144 A ES 552144A ES 552144 A ES552144 A ES 552144A ES 8800252 A1 ES8800252 A1 ES 8800252A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- hydroxyl
- phenyl
- amino
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002401 hexose derivatives Chemical class 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 8
- 239000001257 hydrogen Substances 0.000 abstract 8
- -1 phenyl- Chemical group 0.000 abstract 7
- 150000002431 hydrogen Chemical class 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- WQZGKKKJIJFFOK-SVZMEOIVSA-N (+)-Galactose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@H]1O WQZGKKKJIJFFOK-SVZMEOIVSA-N 0.000 abstract 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 2
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 2
- 125000001589 carboacyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- WQZGKKKJIJFFOK-QTVWNMPRSA-N D-mannopyranose Chemical compound OC[C@H]1OC(O)[C@@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-QTVWNMPRSA-N 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 125000004063 butyryl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000002402 hexoses Chemical group 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 150000003215 pyranoses Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003258 trimethylene group Chemical group [H]C([H])([*:2])C([H])([H])C([H])([H])[*:1] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/005—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure containing within the molecule the substructure with m, n > 0 and m+n > 0, A, B, D, E being heteroatoms; X being a bond or a chain, e.g. muramylpeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/02—Monosaccharides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA OBTENER DERIVADO DE HEXOSA ACILADOS. CONSISTE EN HACER REACCIONAR A UN COMPUESTO DE FORMULA (II) CON AGENTE DE ACILACION TRANSMISOR DEL RESTO A INTRODUCIR R ELEVADO A 1, EN TOLUENO, EN PRESENCIA DE CARBONATO SODICO Y ENTRE 0 Y 100GC, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y, SUS SALES. SIENDO: R ELEVADO A 1, R ELEVADO A 3, R ELEVADO A 5 Y R ELEVADO A 7, H O ALQUILO INFERIOR; R ELEVADO A 4 Y R ELEVADO A 6, H, ALCANOILO INFERIOR; R ELEVADO A 8 Y R ELEVADO A 11, H O ALQUILO INFERIOR SUSTITUIDO POR FENILO; R ELEVADO A 9 Y R ELEVADO A 12, HIDROXI AMINO; R ELEVADO A 10, H, CARBOXI Y OTROS; R ELEVADO A 1A, R ELEVADO A 2A, R ELEVADO A 4A Y R ELEVADO A 6A, H; Y N, 0 O 1. SE UTILIZA COMO ANTIVIRICOS EN VETERINARIA. *FORMULA*
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH77385 | 1985-02-20 | ||
| CH466085 | 1985-10-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8800252A1 true ES8800252A1 (es) | 1987-10-16 |
| ES552144A0 ES552144A0 (es) | 1987-10-16 |
Family
ID=25685637
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES552144A Expired ES8800252A1 (es) | 1985-02-20 | 1986-02-18 | Procedimiento para la obtencion de derivados de hexosa acilados |
| ES557598A Expired ES8800279A1 (es) | 1985-02-20 | 1987-06-16 | Procedimiento para la obtencion de derivados de hexosa acilados |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES557598A Expired ES8800279A1 (es) | 1985-02-20 | 1987-06-16 | Procedimiento para la obtencion de derivados de hexosa acilados |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0192609A3 (es) |
| KR (1) | KR860006480A (es) |
| AU (1) | AU579448B2 (es) |
| DK (1) | DK77286A (es) |
| ES (2) | ES8800252A1 (es) |
| FI (1) | FI860707A7 (es) |
| GR (1) | GR860465B (es) |
| HU (1) | HUT40141A (es) |
| NO (1) | NO860625L (es) |
| NZ (1) | NZ215222A (es) |
| PH (1) | PH23120A (es) |
| PT (1) | PT82043B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2732604B1 (fr) * | 1995-04-07 | 1997-06-06 | Vacsyn Sa | Derives et conjugues du mdp presentant une activite stimulatrice de la fonction hematopoietique et compositions les contenant |
| EP1843760A4 (en) * | 2005-02-04 | 2009-03-25 | Alchemia Ltd | CLASSES OF COMPOUNDS THAT INTERACT WITH THE INTEGRINS |
| CA3021645A1 (en) | 2016-04-29 | 2017-11-02 | Icahn School Of Medicine At Mount Sinai | Targeting the innate immune system to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis |
| AU2022239614A1 (en) | 2021-03-19 | 2023-10-12 | Icahn School Of Medicine At Mount Sinai | Compounds for regulating trained immunity, and their methods of use |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4186194A (en) * | 1973-10-23 | 1980-01-29 | Agence Nationale De Valorisation De La Recherche (Anvar) | Water soluble agents effective as immunological adjuvants for stimulating, in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents |
| US4153684A (en) * | 1976-03-10 | 1979-05-08 | Agence Nationale De Valorisation De La Recherche (Anvar) | Immunizing and anti-infectious adjuvant agents constituted by N-acetyl-muramyl-L-alanyl-D-glutamic acid derivatives |
| FR2442241A2 (fr) * | 1978-03-20 | 1980-06-20 | Anvar | Nouveaux composes esters de muramyl-peptide, leur preparation et les compositions pharmaceutiques les contenant, notamment sous forme de liposomes |
| FI860708A7 (fi) * | 1985-02-20 | 1986-08-21 | Ciba Geigy Ag | Acylerade hexosderivat och foerfarande foer deras framstaellning. |
-
1986
- 1986-02-14 EP EP86810082A patent/EP0192609A3/de not_active Withdrawn
- 1986-02-17 FI FI860707A patent/FI860707A7/fi not_active IP Right Cessation
- 1986-02-18 GR GR860465A patent/GR860465B/el unknown
- 1986-02-18 ES ES552144A patent/ES8800252A1/es not_active Expired
- 1986-02-18 PT PT82043A patent/PT82043B/pt unknown
- 1986-02-18 PH PH33428A patent/PH23120A/en unknown
- 1986-02-19 HU HU86696A patent/HUT40141A/hu unknown
- 1986-02-19 DK DK77286A patent/DK77286A/da not_active Application Discontinuation
- 1986-02-19 KR KR1019860001148A patent/KR860006480A/ko not_active Withdrawn
- 1986-02-19 NZ NZ215222A patent/NZ215222A/xx unknown
- 1986-02-19 NO NO86860625A patent/NO860625L/no unknown
- 1986-02-19 AU AU53767/86A patent/AU579448B2/en not_active Ceased
-
1987
- 1987-06-16 ES ES557598A patent/ES8800279A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK77286A (da) | 1986-08-21 |
| ES8800279A1 (es) | 1987-10-16 |
| EP0192609A2 (de) | 1986-08-27 |
| EP0192609A3 (de) | 1988-04-27 |
| GR860465B (en) | 1986-06-13 |
| FI860707A0 (fi) | 1986-02-17 |
| DK77286D0 (da) | 1986-02-19 |
| FI860707A7 (fi) | 1986-08-21 |
| ES557598A0 (es) | 1987-10-16 |
| HUT40141A (en) | 1986-11-28 |
| KR860006480A (ko) | 1986-09-11 |
| PH23120A (en) | 1989-05-05 |
| AU579448B2 (en) | 1988-11-24 |
| PT82043A (de) | 1986-03-01 |
| ES552144A0 (es) | 1987-10-16 |
| NO860625L (no) | 1986-08-21 |
| NZ215222A (en) | 1989-08-29 |
| AU5376786A (en) | 1986-08-28 |
| PT82043B (de) | 1987-11-09 |
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