ES8800960A1 - Un metodo para preparar un extracto acidulado de tejido humano. - Google Patents

Un metodo para preparar un extracto acidulado de tejido humano.

Info

Publication number
ES8800960A1
ES8800960A1 ES554177A ES554177A ES8800960A1 ES 8800960 A1 ES8800960 A1 ES 8800960A1 ES 554177 A ES554177 A ES 554177A ES 554177 A ES554177 A ES 554177A ES 8800960 A1 ES8800960 A1 ES 8800960A1
Authority
ES
Spain
Prior art keywords
acidulated
growth
human tissue
polypeptides
recover
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES554177A
Other languages
English (en)
Other versions
ES554177A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OSI Pharmaceuticals LLC
Original Assignee
Oncogene Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogene Science Inc filed Critical Oncogene Science Inc
Publication of ES554177A0 publication Critical patent/ES554177A0/es
Publication of ES8800960A1 publication Critical patent/ES8800960A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

METODO DE PREPARACION DE EXTRACTOS ETANOLICOS ACIDULADOS DE TEJIDO HUMANO. CONSISTE EN TRATAR EL TEJIDO HUMANO POR SUSPENSION EN UN TAMPON DE EXTRACCION ACIDO QUE CONTIENE ETANOL A UNOS 4JC, HOMOGENEIZAR Y AGITAR DURANTE UN TIEMPO ADECUADO PARA PRODUCIR PROTEINAS SOLUBILIZADAS; RECUPERAR DICHAS PROTEINAS; RECUPERAR DE ESTAS POLIPEPTIDOS CUYO PESO MOLECULAR APARENTE ES MENOR QUE 30.000 DALTONS; ENSAYAR LOS POLIPEPTIDOS RECUPERADOS PARA IDENTIFICAR LOS QUE INHIBEN EL CRECIMIENTO DE CELULAS TUMORALES HUMANAS O DE UNA LINEA DE CELULAS DE PULMON DE VISON, O PROMUEVEN EL CRECIMIENTO DE FIBROPLASTOS DE PREPUCIO HUMANO; Y RECUPERAR EL EXTRACTO ETANOLICO ACIDULADO QUE CONTIENE DICHOS POLIPEPTIDOS. ESTOS EXTRACTOS TIENEN APLICACIONES POR SU ACTIVIDAD INHIBIDORA DEL CRECIMIENTO DE TUMORES.
ES554177A 1985-04-19 1986-04-18 Un metodo para preparar un extracto acidulado de tejido humano. Expired ES8800960A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72500385A 1985-04-19 1985-04-19
US84793186A 1986-04-07 1986-04-07

Publications (2)

Publication Number Publication Date
ES554177A0 ES554177A0 (es) 1987-12-01
ES8800960A1 true ES8800960A1 (es) 1987-12-01

Family

ID=27111075

Family Applications (1)

Application Number Title Priority Date Filing Date
ES554177A Expired ES8800960A1 (es) 1985-04-19 1986-04-18 Un metodo para preparar un extracto acidulado de tejido humano.

Country Status (10)

Country Link
EP (1) EP0200090B1 (es)
JP (1) JPH0788397B2 (es)
AT (1) ATE83152T1 (es)
AU (1) AU600230B2 (es)
CA (1) CA1274471A (es)
DE (1) DE3687241T2 (es)
ES (1) ES8800960A1 (es)
IE (1) IE60059B1 (es)
IL (1) IL78546A0 (es)
NZ (1) NZ215887A (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5284763A (en) * 1985-03-22 1994-02-08 Genentech, Inc. Nucleic acid encoding TGF-β and its uses
US4886747A (en) * 1985-03-22 1989-12-12 Genentech, Inc. Nucleic acid encoding TGF-β and its uses
NZ222168A (en) * 1986-10-20 1991-05-28 Oncogene Science Inc Tumour growth inhibiting protein related to tgf-#b#1 and tgf-#b#2, preparation by genetic engineering methods, antibodies and pharmaceutical compositions
DE3907822A1 (de) * 1989-03-10 1990-09-13 Adolf Dr Loefflmann Verwendung einer peroxidaseaktivitaet zeigenden proteinfraktion aus dem photosyntheseapparat von pflanzen als arzneimittel, insbesondere zur krebsbekaempfung, sowie verfahren zur gewinnung einer proteinmischung und arzneimittel zur krebsbekaempfung
GB9106678D0 (en) * 1991-03-28 1991-05-15 Ferguson Mark W J Wound healing
RU2065307C1 (ru) * 1994-12-13 1996-08-20 Александр Васильевич Тихонов Способ лечения первичного рака печени и набор для лечения первичного рака печени
JP2002539172A (ja) 1999-03-17 2002-11-19 ノバルティス アクチエンゲゼルシャフト Ｔｇｆ−ベータを含む医薬組成物
RU2240810C2 (ru) * 2002-01-30 2004-11-27 Левон Никитович Мкртчян Эмбриональный противоопухолевый модулятор мкртчяна, способ его получения и применения

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5221570B2 (es) * 1973-08-30 1977-06-11
CA1230591A (en) * 1983-06-03 1987-12-22 Charles A. Frolik PURIFIED TRANSFORMING GROWTH FACTOR-.beta. DERIVED FROM HUMAN PLATELETS AND PLACENTAS
US4524026A (en) * 1983-08-29 1985-06-18 Yoshio Sakagami Novel proteinous cancer-cell proliferation inhibitory factors

Also Published As

Publication number Publication date
DE3687241D1 (de) 1993-01-21
IE860971L (en) 1986-10-19
JPH0788397B2 (ja) 1995-09-27
IL78546A0 (en) 1986-08-31
AU5644486A (en) 1986-10-23
DE3687241T2 (de) 1993-07-01
EP0200090A2 (en) 1986-11-05
CA1274471A (en) 1990-09-25
ES554177A0 (es) 1987-12-01
EP0200090B1 (en) 1992-12-09
AU600230B2 (en) 1990-08-09
NZ215887A (en) 1991-05-28
ATE83152T1 (de) 1992-12-15
EP0200090A3 (en) 1988-05-04
IE60059B1 (en) 1994-05-18
JPS6223A (ja) 1987-01-06

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Legal Events

Date Code Title Description
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20070918