FI104379B - Menetelmä ja materiaaleja tolueenin ja muiden fenyyliyhdisteiden biokonvertoimiseksi - Google Patents

Menetelmä ja materiaaleja tolueenin ja muiden fenyyliyhdisteiden biokonvertoimiseksi Download PDF

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Publication number
FI104379B
FI104379B FI895788A FI895788A FI104379B FI 104379 B FI104379 B FI 104379B FI 895788 A FI895788 A FI 895788A FI 895788 A FI895788 A FI 895788A FI 104379 B FI104379 B FI 104379B
Authority
FI
Finland
Prior art keywords
toluene
cells
microorganism host
plasmid
recombinant plasmid
Prior art date
Application number
FI895788A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI895788A0 (fi
Inventor
Kwang-Mu Yen
Lawrence M Blatt
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Amgen Inc filed Critical Amgen Inc
Publication of FI895788A0 publication Critical patent/FI895788A0/fi
Application granted granted Critical
Publication of FI104379B publication Critical patent/FI104379B/fi

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
    • C12P7/12—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate substrate containing sulfite waste liquor or citrus waste
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/874—Pseudomonas

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
FI895788A 1988-04-05 1989-12-04 Menetelmä ja materiaaleja tolueenin ja muiden fenyyliyhdisteiden biokonvertoimiseksi FI104379B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/177,631 US5017495A (en) 1988-04-05 1988-04-05 Plasmid encoding the Pseudomonas mendocina toluene monooxygenase gene
US17763188 1988-04-05
US8901445 1989-04-04
PCT/US1989/001445 WO1989009828A1 (en) 1988-04-05 1989-04-04 Method and materials for the microbial bioconversion of toluene and other phenyl compounds

Publications (2)

Publication Number Publication Date
FI895788A0 FI895788A0 (fi) 1989-12-04
FI104379B true FI104379B (fi) 2000-01-14

Family

ID=22649341

Family Applications (1)

Application Number Title Priority Date Filing Date
FI895788A FI104379B (fi) 1988-04-05 1989-12-04 Menetelmä ja materiaaleja tolueenin ja muiden fenyyliyhdisteiden biokonvertoimiseksi

Country Status (12)

Country Link
US (1) US5017495A (da)
EP (1) EP0336719A3 (da)
JP (1) JP2862301B2 (da)
KR (1) KR0157301B1 (da)
AU (1) AU625220B2 (da)
CA (1) CA1337977C (da)
DK (1) DK175789B1 (da)
FI (1) FI104379B (da)
IL (1) IL89845A (da)
NO (1) NO301548B1 (da)
WO (1) WO1989009828A1 (da)
ZA (1) ZA892503B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171684A (en) * 1988-04-05 1992-12-15 Amgen Inc. Bioconversions catalyzed by the toluene monooxygenase of Pseudomanas mendocina KR-1
JPH05502590A (ja) * 1990-09-28 1993-05-13 アムジエン・インコーポレーテツド グラム陰性菌におけるクローニング・カートリッジおよび発現ベクター
US6642031B2 (en) 1995-11-20 2003-11-04 Genencor International, Inc. Microorganisms with ability to degrade indole and enzymes therefrom
US6190892B1 (en) * 1995-11-20 2001-02-20 Genencor International, Inc. Microbial production of indigo
US5958757A (en) * 1996-09-13 1999-09-28 Envirogen, Inc. Biological conversion of organic compounds
DE69738255T2 (de) * 1996-09-25 2008-08-14 Genencor International, Inc., Palo Alto Mikroorganismen, die die fähigkeit besitzen, indol zu degradieren und extrakte daraus, die eine indoloxidase-aktivität haben
US6551814B1 (en) 1997-05-05 2003-04-22 Ohio University Methods for bioremediation by degrading toluene
US6395539B1 (en) 1997-05-05 2002-05-28 Ohio University Composition and methods for bioremediation
US6830899B1 (en) 1997-06-13 2004-12-14 E. I. Du Pont De Nemours And Company Method for the production of para-hydroxybenzoate in Pseudomonas mendocina
EP1032677A1 (en) * 1997-10-31 2000-09-06 E.I. Du Pont De Nemours And Company A gene encoding a putative efflux protein for solvents/antibiotics in pseudomonas mendocina
AU1133900A (en) 1998-10-26 2000-07-12 University Of Iowa Research Foundation, The Novel naphthalene dioxygenase and methods for their use
US6586229B1 (en) 2000-06-01 2003-07-01 North Carolina State University Method for the production of ρ-Hydroxybenzoate in species of pseudomonas and agrobacterium
AU2001276210A1 (en) * 2000-07-18 2002-01-30 National Research Council Of Canada Cloning, sequencing and expression of a comamonas cyclopentanone 1,2-monooxygenase-encoding gene in escherichia coli

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1436573A (en) * 1972-06-07 1976-05-19 Gen Electric Microorganisms
US4477570A (en) * 1981-09-24 1984-10-16 Occidental Chemical Corporation Microbial degradation of obnoxious organic wastes into innocucous materials
JPS59501732A (ja) * 1982-09-20 1984-10-18 アムジエン 芳香族炭化水素類の微生物学的酸化のための方法および材料
US4520103A (en) * 1982-10-27 1985-05-28 Amgen Microbial production of indigo
US4959315A (en) * 1987-04-30 1990-09-25 The United States Of America As Represented By The Administrator Of The Environmental Protection Agency Biodegradation of chloroethylene compounds

Also Published As

Publication number Publication date
DK609089A (da) 1990-01-24
WO1989009828A1 (en) 1989-10-19
US5017495A (en) 1991-05-21
ZA892503B (en) 1991-12-24
NO894845L (no) 1990-02-02
AU3410489A (en) 1989-11-03
FI895788A0 (fi) 1989-12-04
DK609089D0 (da) 1989-12-04
KR900700612A (ko) 1990-08-16
NO894845D0 (no) 1989-12-04
JP2862301B2 (ja) 1999-03-03
JPH03500126A (ja) 1991-01-17
DK175789B1 (da) 2005-02-21
IL89845A0 (en) 1989-12-15
NO301548B1 (no) 1997-11-10
EP0336719A2 (en) 1989-10-11
KR0157301B1 (ko) 1998-10-15
IL89845A (en) 1994-11-28
EP0336719A3 (en) 1989-11-15
CA1337977C (en) 1996-01-23
AU625220B2 (en) 1992-07-02

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Owner name: AMGEN INC.

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