FI20011908A7 - Method for detecting stomach cancer - Google Patents

Method for detecting stomach cancer Download PDF

Info

Publication number
FI20011908A7
FI20011908A7 FI20011908A FI20011908A FI20011908A7 FI 20011908 A7 FI20011908 A7 FI 20011908A7 FI 20011908 A FI20011908 A FI 20011908A FI 20011908 A FI20011908 A FI 20011908A FI 20011908 A7 FI20011908 A7 FI 20011908A7
Authority
FI
Finland
Prior art keywords
individual
cellular fibronectin
value
stomach cancer
detecting
Prior art date
Application number
FI20011908A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI20011908L (en
FI20011908A0 (en
Inventor
Osmo Suovaniemi
Matti Härkönen
Pentti Sipponen
Original Assignee
Biohit Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biohit Oyj filed Critical Biohit Oyj
Priority to FI20011908A priority Critical patent/FI20011908L/en
Publication of FI20011908A0 publication Critical patent/FI20011908A0/en
Priority to PCT/FI2002/000773 priority patent/WO2003029826A1/en
Publication of FI20011908A7 publication Critical patent/FI20011908A7/en
Publication of FI20011908L publication Critical patent/FI20011908L/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5753—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the stomach or small intestine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/595—Gastrins; Cholecystokinins [CCK]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96472—Aspartic endopeptidases (3.4.23)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Keksintö koskee menetelmä syövän osoittamiseksi tai seulomiseksi yksilöllä, jossa menetelmässä määritetään mainitun yksilön mahan limakalvon gastriittifenotyyppi, määritetään solufibronektiinipitoisuus mainitusta yksilöstä otetusta näytteestä, kuten seeruminäytteestä, valitaan cut-off-arvo solufibronektiinille ja verrataan solufibronektiinipitoisuutta valittuun cut-off-arvoon. Atrofisen gastriitin tila yhdessä solufibronektiinipitoisuuden, joka on yli valitun cut-off-arvon, kanssa on sitten osoitus mahasyövästä mainitulla yksilöllä.The invention relates to a method for detecting or screening for cancer in an individual, the method comprising determining a gastritis phenotype of the gastric mucosa of said individual, determining the cellular fibronectin content of a sample taken from said individual, such as a serum sample, selecting a cut-off value for cellular fibronectin, and comparing the cellular fibronectin content to the selected cut-off value. A state of atrophic gastritis in combination with a cellular fibronectin content above the selected cut-off value is then indicative of gastric cancer in said individual.

FI20011908A 2001-09-28 2001-09-28 Method for detecting stomach cancer FI20011908L (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI20011908A FI20011908L (en) 2001-09-28 2001-09-28 Method for detecting stomach cancer
PCT/FI2002/000773 WO2003029826A1 (en) 2001-09-28 2002-09-30 Method for detecting a cancer or precancerous condition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20011908A FI20011908L (en) 2001-09-28 2001-09-28 Method for detecting stomach cancer

Publications (3)

Publication Number Publication Date
FI20011908A0 FI20011908A0 (en) 2001-09-28
FI20011908A7 true FI20011908A7 (en) 2003-03-29
FI20011908L FI20011908L (en) 2003-03-29

Family

ID=8561972

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20011908A FI20011908L (en) 2001-09-28 2001-09-28 Method for detecting stomach cancer

Country Status (2)

Country Link
FI (1) FI20011908L (en)
WO (1) WO2003029826A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI119572B (en) * 2004-03-05 2008-12-31 Biohit Oyj Method for predicting the condition of the gastric mucosa
CA3193501A1 (en) * 2015-12-31 2017-07-06 Progastrine Et Cancers S.A R.L. Compositions and methods for detecting and treating gastric cancer
CN111638366B (en) * 2020-04-30 2021-02-19 吉林省格瑞斯特生物技术有限公司 G-17, PGI and PGII combined detection device and preparation method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5420012A (en) * 1989-05-08 1995-05-30 Locus Genex Oy Method for the detection of reactive conditions
FI97304C (en) * 1994-11-16 1996-11-25 Locus Genex Oy Procedure for screening cancer risk

Also Published As

Publication number Publication date
WO2003029826A1 (en) 2003-04-10
FI20011908L (en) 2003-03-29
FI20011908A0 (en) 2001-09-28

Similar Documents

Publication Publication Date Title
ATE269977T1 (en) BINDING ACCELERATION METHOD FOR DETECTING ANALYTES
DE60230672D1 (en) NUCLEIC ENRICHMENT
WO2008041953A3 (en) Dengue diagnosis and treatment
WO2002047535A3 (en) High throughput assay to detect inhibitors of the map kinase pathway
IL181132A0 (en) Use of transthyretin as a biomarker for colorectal adenoma and/or carcinoma; method for detection and test system
DE60033555D1 (en) METHOD AND COMPOSITIONS FOR DETECTING AND TREATING BREAST CANCER BASED ON BREAST CANCER ASSOCIATED POLYPEPTIDES
WO2004033631A8 (en) Nucleic acid and polypeptide sequences from lawsonia intracellularis and methods of using
PL2185937T5 (en) Method for assaying sepsis in humans
DE602004021281D1 (en) COLORIMETRIC SUBSTRATES, COLORIMETRIC SENSORS AND METHOD OF USE
WO2004057336A3 (en) Use of nicotinamide n-methyltransferase as a marker for colorectal cancer
AU2003280694A1 (en) Urothelial cancer tumor marker
EA200600459A1 (en) METHOD FOR OBTAINING CYTOTOXIC LYMPHOCYTES
NO20034278L (en) Compositions and Methods for Treating HCV Infections
WO2004022006A3 (en) Methods of diagnosing cervical cancer
ATE221657T1 (en) DISTURBANCE BY RHEUMA FACTORS
EA200900714A1 (en) ION SENSOR FOR FLUID ENVIRONMENT AND METHOD FOR ITS MANUFACTURE
ATE288587T1 (en) METHOD FOR DETERMINING LIPID UPtake
ATE449868T1 (en) METHODS, TEST SETS AND COMPOSITIONS FOR DETECTING AND QUANTIFYING TARGET SEQUENCES
DE69739956D1 (en) Calcium activated potassium channel with intermediate conductance and uses thereof
FI20011908L (en) Method for detecting stomach cancer
IL189185A0 (en) Use of an endoplasmin fragment and derivatives thereof as a biomarker for colorectal adenoma and/or carcinoma; method for detection and test system
NO20052553L (en) Cobalaminanalyse.
DE50305041D1 (en) METHOD FOR THE DETECTION AND CONCENTRATION DETERMINATION OF SWEEP-FREE ODORANCES IN NATURAL OR COMBUSTION GAS
GB0323171D0 (en) Fluorescent compound
WO2004070389A8 (en) Assay for protein isoforms