FI20011908L - Method for detecting stomach cancer - Google Patents

Method for detecting stomach cancer Download PDF

Info

Publication number
FI20011908L
FI20011908L FI20011908A FI20011908A FI20011908L FI 20011908 L FI20011908 L FI 20011908L FI 20011908 A FI20011908 A FI 20011908A FI 20011908 A FI20011908 A FI 20011908A FI 20011908 L FI20011908 L FI 20011908L
Authority
FI
Finland
Prior art keywords
individual
cellular fibronectin
concentration
gastric
value
Prior art date
Application number
FI20011908A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI20011908A0 (en
FI20011908A7 (en
Inventor
Osmo Suovaniemi
Matti Haerkoenen
Pentti Sipponen
Original Assignee
Biohit Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biohit Oyj filed Critical Biohit Oyj
Priority to FI20011908A priority Critical patent/FI20011908L/en
Publication of FI20011908A0 publication Critical patent/FI20011908A0/en
Priority to PCT/FI2002/000773 priority patent/WO2003029826A1/en
Publication of FI20011908A7 publication Critical patent/FI20011908A7/en
Publication of FI20011908L publication Critical patent/FI20011908L/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5753—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the stomach or small intestine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/595—Gastrins; Cholecystokinins [CCK]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96472—Aspartic endopeptidases (3.4.23)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A method for detecting or screening cancer in an individual is described, which method comprises determining the gastritis phenotype of the gastric mucosa of the said individual, determining the cellular fibronectin concentration in a sample such as a serum sample of said individual, selecting a cut−off value for cellular fibronectin, and comparing the cellular fibronectin concentration to the selected cutoff value. A combination of a condition of atrophic gastritis and a concentration of cellular fibronectin above the selected cut­off value is then indicative of gastric cancer in said individual. The gastric phenotype of the gastric mucosa is determined by an analysis of the pepsinogen I and gastrin−17 levels in said individual.
FI20011908A 2001-09-28 2001-09-28 Method for detecting stomach cancer FI20011908L (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI20011908A FI20011908L (en) 2001-09-28 2001-09-28 Method for detecting stomach cancer
PCT/FI2002/000773 WO2003029826A1 (en) 2001-09-28 2002-09-30 Method for detecting a cancer or precancerous condition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI20011908A FI20011908L (en) 2001-09-28 2001-09-28 Method for detecting stomach cancer

Publications (3)

Publication Number Publication Date
FI20011908A0 FI20011908A0 (en) 2001-09-28
FI20011908A7 FI20011908A7 (en) 2003-03-29
FI20011908L true FI20011908L (en) 2003-03-29

Family

ID=8561972

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20011908A FI20011908L (en) 2001-09-28 2001-09-28 Method for detecting stomach cancer

Country Status (2)

Country Link
FI (1) FI20011908L (en)
WO (1) WO2003029826A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI119572B (en) * 2004-03-05 2008-12-31 Biohit Oyj Method for predicting the condition of the gastric mucosa
KR102477179B1 (en) 2015-12-31 2022-12-13 프로가스트린 에 캔서스 에스.에이 알.엘. Compositions and methods for detecting and treating gastric cancer
CN111638366B (en) * 2020-04-30 2021-02-19 吉林省格瑞斯特生物技术有限公司 G-17, PGI and PGII combined detection device and preparation method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5420012A (en) * 1989-05-08 1995-05-30 Locus Genex Oy Method for the detection of reactive conditions
FI97304C (en) * 1994-11-16 1996-11-25 Locus Genex Oy Procedure for screening cancer risk

Also Published As

Publication number Publication date
FI20011908A0 (en) 2001-09-28
FI20011908A7 (en) 2003-03-29
WO2003029826A1 (en) 2003-04-10

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