FI80276C - Mot denaturering skyddade vattenloesningar av proteiner, foerfarande foer deras framstaellning och deras anvaendning. - Google Patents

Mot denaturering skyddade vattenloesningar av proteiner, foerfarande foer deras framstaellning och deras anvaendning. Download PDF

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Publication number
FI80276C
FI80276C FI842798A FI842798A FI80276C FI 80276 C FI80276 C FI 80276C FI 842798 A FI842798 A FI 842798A FI 842798 A FI842798 A FI 842798A FI 80276 C FI80276 C FI 80276C
Authority
FI
Finland
Prior art keywords
proteins
protein
solution
formula
aqueous solution
Prior art date
Application number
FI842798A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI842798A7 (fi
FI80276B (fi
FI842798A0 (fi
Inventor
Horst Thurow
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI842798A0 publication Critical patent/FI842798A0/fi
Publication of FI842798A7 publication Critical patent/FI842798A7/fi
Application granted granted Critical
Publication of FI80276B publication Critical patent/FI80276B/fi
Publication of FI80276C publication Critical patent/FI80276C/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591—Stabilisation, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01023—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
FI842798A 1983-07-13 1984-07-11 Mot denaturering skyddade vattenloesningar av proteiner, foerfarande foer deras framstaellning och deras anvaendning. FI80276C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833325223 DE3325223A1 (de) 1983-07-13 1983-07-13 Gegen denaturierung bestaendige, waessrige proteinloesungen, verfahren zu ihrer herstellung und ihre verwendung
DE3325223 1984-07-11

Publications (4)

Publication Number Publication Date
FI842798A0 FI842798A0 (fi) 1984-07-11
FI842798A7 FI842798A7 (fi) 1985-01-14
FI80276B FI80276B (fi) 1990-01-31
FI80276C true FI80276C (fi) 1990-05-10

Family

ID=6203842

Family Applications (1)

Application Number Title Priority Date Filing Date
FI842798A FI80276C (fi) 1983-07-13 1984-07-11 Mot denaturering skyddade vattenloesningar av proteiner, foerfarande foer deras framstaellning och deras anvaendning.

Country Status (15)

Country Link
US (1) US4637834A (2)
EP (1) EP0131864B1 (2)
JP (1) JPS6038398A (2)
KR (1) KR920002934B1 (2)
AT (1) ATE56876T1 (2)
AU (1) AU579106B2 (2)
DE (2) DE3325223A1 (2)
DK (1) DK168030B1 (2)
ES (2) ES534195A0 (2)
FI (1) FI80276C (2)
GR (1) GR81504B (2)
IE (1) IE57694B1 (2)
IL (1) IL72389A (2)
PT (1) PT78892A (2)
ZA (1) ZA845384B (2)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0018609B1 (de) * 1979-04-30 1983-09-21 Hoechst Aktiengesellschaft Gegen Denaturierung beständige, wässrige Protein-Lösungen, Verfahren zu ihrer Herstellung und ihre Verwendung
JPS61277633A (ja) * 1985-05-31 1986-12-08 Toray Ind Inc インタ−フエロン組成物
US5183746A (en) * 1986-10-27 1993-02-02 Schering Aktiengesellschaft Formulation processes for pharmaceutical compositions of recombinant β-
US4956274A (en) * 1987-04-06 1990-09-11 Microgenics Corporation Reagent stabilization in enzyme-donor and acceptor assay
US5004605A (en) * 1987-12-10 1991-04-02 Cetus Corporation Low pH pharmaceutical compositions of recombinant β-interferon
US5763394A (en) * 1988-04-15 1998-06-09 Genentech, Inc. Human growth hormone aqueous formulation
US5981485A (en) 1997-07-14 1999-11-09 Genentech, Inc. Human growth hormone aqueous formulation
US5078997A (en) * 1988-07-13 1992-01-07 Cetus Corporation Pharmaceutical composition for interleukin-2 containing physiologically compatible stabilizers
US5945098A (en) * 1990-02-01 1999-08-31 Baxter International Inc. Stable intravenously-administrable immune globulin preparation
US5830452A (en) * 1990-11-20 1998-11-03 Chiron Corporation Method for enhancing the anti-tumor therapeutic index of interleukin-2
CA2133737A1 (en) * 1992-04-07 1993-10-14 James E. Seely Lyophilized somatotropin formulations
MD1699F2 (ro) * 1992-07-31 2001-07-31 Genentech, Inc. Compoziţie apoasă a hormonului somatotrop uman şi procedeu de prevenire a denaturării ei
US6790439B1 (en) 1995-06-07 2004-09-14 Zymogenetics, Inc. Thrombopoietin compositions
EP0837883B1 (en) * 1995-06-07 2005-08-10 Chiron Corporation Method of solubilizing, purifying, and refolding protein
MX9602398A (es) * 1995-06-23 1997-02-28 Kimberly Clark Co Material polimerico modificado teniendo humectabilidad mejorada.
AUPN801296A0 (en) * 1996-02-12 1996-03-07 Csl Limited Stabilised growth hormone formulation and method of preparation thereof
CA2378949C (en) * 1999-07-12 2015-03-31 Grandis Biotech Gmbh Growth hormone formulations
AU2003249992A1 (en) * 2002-07-09 2004-01-23 Sandoz Ag Liquid formulations with high concentration of human growth hormone (hgh) comprising phenol
US7851433B2 (en) * 2003-08-13 2010-12-14 Novartis Vaccines And Diagnostics, Inc. Method of purifying TFPI and TFPI analogs
UA89781C2 (uk) 2004-04-07 2010-03-10 Арес Трейдінг С.А. Рідкий склад гормона росту
EP1847830A1 (en) * 2006-04-20 2007-10-24 TF Instruments, Inc. Determining optimal concentrations of protective additives for biomolecules
WO2024133849A1 (en) * 2022-12-22 2024-06-27 The Protein Brewery B.V. Ovalbumin fermentation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4439355A (en) * 1976-12-02 1984-03-27 Colgate-Palmolive Company Elastic detergent product of improved foaming power after use
EP0018609B1 (de) * 1979-04-30 1983-09-21 Hoechst Aktiengesellschaft Gegen Denaturierung beständige, wässrige Protein-Lösungen, Verfahren zu ihrer Herstellung und ihre Verwendung
DE2917535C2 (de) * 1979-04-30 1986-10-30 Hoechst Ag, 6230 Frankfurt Gegen Denaturierung beständige Insulinlösungen
AU558474B2 (en) * 1981-07-17 1987-01-29 Nordisk Insulinlaboratorium A stable aqueous, therapeutic insulin preparation and a process for preparing it

Also Published As

Publication number Publication date
FI842798A7 (fi) 1985-01-14
EP0131864A3 (en) 1987-08-26
JPS6038398A (ja) 1985-02-27
ES535482A0 (es) 1986-09-01
AU579106B2 (en) 1988-11-17
ES8600319A1 (es) 1985-10-01
IE841796L (en) 1985-01-13
DK168030B1 (da) 1994-01-24
EP0131864B1 (de) 1990-09-26
ZA845384B (en) 1985-02-27
IL72389A (en) 1988-11-30
AU3053784A (en) 1985-01-17
KR850000971A (ko) 1985-03-14
DK342684D0 (da) 1984-07-12
KR920002934B1 (ko) 1992-04-10
IL72389A0 (en) 1984-11-30
DE3325223A1 (de) 1985-01-24
FI80276B (fi) 1990-01-31
DE3483287D1 (de) 1990-10-31
ATE56876T1 (de) 1990-10-15
GR81504B (2) 1984-12-11
EP0131864A2 (de) 1985-01-23
ES8609361A1 (es) 1986-09-01
JPH0582397B2 (2) 1993-11-18
ES534195A0 (es) 1985-10-01
FI842798A0 (fi) 1984-07-11
IE57694B1 (en) 1993-03-10
US4637834A (en) 1987-01-20
DK342684A (da) 1985-01-14
PT78892A (de) 1984-08-01

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