FI863189L - Benmorfogenetiska aemnen. - Google Patents

Benmorfogenetiska aemnen. Download PDF

Info

Publication number
FI863189L
FI863189L FI863189A FI863189A FI863189L FI 863189 L FI863189 L FI 863189L FI 863189 A FI863189 A FI 863189A FI 863189 A FI863189 A FI 863189A FI 863189 L FI863189 L FI 863189L
Authority
FI
Finland
Prior art keywords
benmorphogenetic
aemnen
benmorphogenetic aemnen
Prior art date
Application number
FI863189A
Other languages
English (en)
Finnish (fi)
Other versions
FI863189A0 (fi
FI863189A7 (fi
Inventor
Marshall R Urist
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of FI863189A0 publication Critical patent/FI863189A0/fi
Publication of FI863189A7 publication Critical patent/FI863189A7/fi
Publication of FI863189L publication Critical patent/FI863189L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/84—Bones; tendons; teeth; cartilage

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
FI863189A 1985-08-07 1986-08-05 Benmorfogenetiska aemnen. FI863189L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/763,479 US4795804A (en) 1983-08-16 1985-08-07 Bone morphogenetic agents

Publications (3)

Publication Number Publication Date
FI863189A0 FI863189A0 (fi) 1986-08-05
FI863189A7 FI863189A7 (fi) 1987-02-08
FI863189L true FI863189L (fi) 1987-02-08

Family

ID=25067940

Family Applications (1)

Application Number Title Priority Date Filing Date
FI863189A FI863189L (fi) 1985-08-07 1986-08-05 Benmorfogenetiska aemnen.

Country Status (6)

Country Link
US (1) US4795804A (de)
EP (1) EP0212474A3 (de)
JP (1) JPS62111933A (de)
DK (1) DK374686A (de)
FI (1) FI863189L (de)
NO (1) NO863185L (de)

Families Citing this family (119)

* Cited by examiner, † Cited by third party
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US5187076A (en) * 1986-07-01 1993-02-16 Genetics Institute, Inc. DNA sequences encoding BMP-6 proteins
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US4877864A (en) * 1987-03-26 1989-10-31 Genetics Institute, Inc. Osteoinductive factors
US5106748A (en) * 1986-07-01 1992-04-21 Genetics Institute, Inc. Dna sequences encoding 5 proteins
US6432919B1 (en) * 1986-07-01 2002-08-13 Genetics Institute, Inc. Bone morphogenetic protein-3 and compositions
US5035901A (en) * 1987-10-09 1991-07-30 University Of Kansas Bone inducing agent from a human osteosarcoma cell line
US6020313A (en) * 1987-10-09 2000-02-01 University Of Kansas Method for inducing bone formation using an extract of human osteosarcoma cell line SAOS-2
IL89869A0 (en) * 1988-04-06 1989-12-15 Collagen Corp Bone-inducing protein
US5354557A (en) * 1988-04-08 1994-10-11 Stryker Corporation Osteogenic devices
US5108753A (en) * 1988-04-08 1992-04-28 Creative Biomolecules Osteogenic devices
US5250302A (en) * 1988-04-08 1993-10-05 Stryker Corporation Osteogenic devices
US6919308B2 (en) 1988-04-08 2005-07-19 Stryker Corporation Osteogenic devices
US6586388B2 (en) 1988-04-08 2003-07-01 Stryker Corporation Method of using recombinant osteogenic protein to repair bone or cartilage defects
US4975526A (en) * 1989-02-23 1990-12-04 Creative Biomolecules, Inc. Bone collagen matrix for zenogenic implants
US5266683A (en) 1988-04-08 1993-11-30 Stryker Corporation Osteogenic proteins
US5670336A (en) * 1988-04-08 1997-09-23 Stryker Corporation Method for recombinant production of osteogenic protein
WO1989009787A2 (en) * 1988-04-08 1989-10-19 Creative Biomolecules, Inc. Osteogenic devices
AU645244B2 (en) * 1988-04-08 1994-01-13 Genetics Institute, Llc Bone and cartilage inductive compositions
US5258494A (en) * 1988-04-08 1993-11-02 Stryker Corporation Osteogenic proteins
US4968590A (en) * 1988-04-08 1990-11-06 Stryker Corporation Osteogenic proteins and polypeptides
US5162114A (en) * 1989-02-23 1992-11-10 Stryker Corporation Bone collagen matrix for xenogenic implants
US5324819A (en) * 1988-04-08 1994-06-28 Stryker Corporation Osteogenic proteins
EP0349048A3 (de) * 1988-06-27 1990-07-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Osteogenische Wachstumsfaktoren, die aus Knochenmark gewonnen werden
US5284756A (en) * 1988-10-11 1994-02-08 Lynn Grinna Heterodimeric osteogenic factor
JP2781997B2 (ja) * 1988-12-06 1998-07-30 寶酒造株式会社 ポリペプチドの製造方法
DK0429570T3 (da) * 1989-03-28 1998-04-27 Genetics Inst Osteoinducerende præparater
JPH03151877A (ja) * 1989-06-02 1991-06-28 Chiron Corp 骨カルシウム沈着因子
CA2020729A1 (en) * 1989-07-19 1991-01-20 Michael C. Kiefer Bone morphogenetic protein
US5487897A (en) * 1989-07-24 1996-01-30 Atrix Laboratories, Inc. Biodegradable implant precursor
US5324519A (en) * 1989-07-24 1994-06-28 Atrix Laboratories, Inc. Biodegradable polymer composition
WO1991002744A1 (en) * 1989-08-21 1991-03-07 Celtrix Laboratories, Inc. Bone-specific protein
WO1991005802A1 (en) * 1989-10-17 1991-05-02 Creative Biomolecules, Inc. Osteogenic devices
US5340934A (en) * 1989-11-03 1994-08-23 The United States Of Americas As Represented By The Secretary Of Health & Human Services CDNA sequences of human bone matrix proteins
US5688678A (en) * 1990-05-16 1997-11-18 Genetics Institute, Inc. DNA encoding and methods for producing BMP-8 proteins
US7378392B1 (en) 1990-05-16 2008-05-27 Genetics Institute, Llc Bone and cartilage inductive proteins
US5645591A (en) 1990-05-29 1997-07-08 Stryker Corporation Synthetic bone matrix
US5364839A (en) * 1990-06-18 1994-11-15 Genetics Institute, Inc. Osteoinductive pharmaceutical formulations
US5067963A (en) * 1990-08-21 1991-11-26 Washington University Method of making live autogenous skeletal replacement parts
EP0550625B1 (de) * 1990-09-26 2003-11-05 Genetics Institute, LLC Bmp-5-derivate
WO1992009697A1 (en) * 1990-11-30 1992-06-11 Celtrix Laboratories, Inc. USE OF A BONE MORPHOGENETIC PROTEIN IN SYNERGISTIC COMBINATION WITH TGF-β FOR BONE REPAIR
US5206023A (en) * 1991-01-31 1993-04-27 Robert F. Shaw Method and compositions for the treatment and repair of defects or lesions in cartilage
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US5290763A (en) * 1991-04-22 1994-03-01 Intermedics Orthopedics/Denver, Inc. Osteoinductive protein mixtures and purification processes
US5563124A (en) * 1991-04-22 1996-10-08 Intermedics Orthopedics/ Denver, Inc. Osteogenic product and process
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US5693615A (en) * 1991-06-05 1997-12-02 The Procter & Gamble Company Therapeutic compositions for osteoinduction
US6287816B1 (en) * 1991-06-25 2001-09-11 Genetics Institute, Inc. BMP-9 compositions
EP0592562B1 (de) * 1991-06-25 1999-01-07 Genetics Institute, Inc. Bmp-9 zusammensetzungen
US5270300A (en) * 1991-09-06 1993-12-14 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone
US20080139474A1 (en) * 1991-11-04 2008-06-12 David Israel Recombinant bone morphogenetic protein heterodimers, compositions and methods of use
WO1993009229A1 (en) 1991-11-04 1993-05-13 Genetics Institute, Inc. Recombinant bone morphogenetic protein heterodimers, compositions and methods of use
EP0728142A4 (de) * 1992-03-18 1997-05-02 Osteosa Inc Neuartiger, aus geweih hergestellte knochenwachstumsfaktor
US6291206B1 (en) * 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
US5681873A (en) * 1993-10-14 1997-10-28 Atrix Laboratories, Inc. Biodegradable polymeric composition
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US20020193338A1 (en) * 1994-02-18 2002-12-19 Goldstein Steven A. In vivo gene transfer methods for wound healing
US5962427A (en) * 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
US5942496A (en) * 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
US6074840A (en) 1994-02-18 2000-06-13 The Regents Of The University Of Michigan Recombinant production of latent TGF-beta binding protein-3 (LTBP-3)
US5763416A (en) * 1994-02-18 1998-06-09 The Regent Of The University Of Michigan Gene transfer into bone cells and tissues
US6551618B2 (en) 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
CA2551185C (en) 1994-03-28 2007-10-30 Sdgi Holdings, Inc. Apparatus and method for anterior spinal stabilization
US6758849B1 (en) * 1995-02-17 2004-07-06 Sdgi Holdings, Inc. Interbody spinal fusion implants
US6034062A (en) * 1997-03-13 2000-03-07 Genetics Institute, Inc. Bone morphogenetic protein (BMP)-9 compositions and their uses
ES2320603T3 (es) 1997-07-30 2009-05-25 Emory University Sistemas de expresion, vectores, adn, proteinas de mineralizacion osea novedosos.
US7923250B2 (en) 1997-07-30 2011-04-12 Warsaw Orthopedic, Inc. Methods of expressing LIM mineralization protein in non-osseous cells
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US6187329B1 (en) 1997-12-23 2001-02-13 Board Of Regents Of The University Of Texas System Variable permeability bone implants, methods for their preparation and use
US6255359B1 (en) 1997-12-23 2001-07-03 Board Of Regents Of The University Of Texas System Permeable compositions and methods for their preparation
US6733767B2 (en) * 1998-03-19 2004-05-11 Merck & Co., Inc. Liquid polymeric compositions for controlled release of bioactive substances
US7128927B1 (en) 1998-04-14 2006-10-31 Qlt Usa, Inc. Emulsions for in-situ delivery systems
US6727224B1 (en) * 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
CA2362049A1 (en) * 1999-02-04 2000-08-10 Sdgi Holdings, Inc. Highly-mineralized osteogenic sponge compositions, and uses thereof
US8226598B2 (en) * 1999-09-24 2012-07-24 Tolmar Therapeutics, Inc. Coupling syringe system and methods for obtaining a mixed composition
DK1223990T3 (da) 1999-10-15 2004-11-29 Inst Genetics Llc Formuleringer af hyaluronsyre til tilförsel af osteogene proteiner
US20030082233A1 (en) * 2000-12-01 2003-05-01 Lyons Karen M. Method and composition for modulating bone growth
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
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US7226587B2 (en) * 2001-06-01 2007-06-05 Wyeth Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
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CN104220046A (zh) 2012-04-11 2014-12-17 感应生物制品股份有限公司 用于生长因子多相释放的体系和方法

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Also Published As

Publication number Publication date
NO863185L (no) 1987-02-09
JPS62111933A (ja) 1987-05-22
DK374686A (da) 1987-04-01
NO863185D0 (no) 1986-08-06
FI863189A0 (fi) 1986-08-05
DK374686D0 (da) 1986-08-06
EP0212474A2 (de) 1987-03-04
US4795804A (en) 1989-01-03
EP0212474A3 (de) 1988-11-17
FI863189A7 (fi) 1987-02-08

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Owner name: THE REGENTS OF THE UNIVERSITY OF