FI863384L - Oculoselektiva -blockerare. - Google Patents

Oculoselektiva -blockerare. Download PDF

Info

Publication number
FI863384L
FI863384L FI863384A FI863384A FI863384L FI 863384 L FI863384 L FI 863384L FI 863384 A FI863384 A FI 863384A FI 863384 A FI863384 A FI 863384A FI 863384 L FI863384 L FI 863384L
Authority
FI
Finland
Prior art keywords
oculose
selective blocker
blocker
selective
Prior art date
Application number
FI863384A
Other languages
English (en)
Finnish (fi)
Other versions
FI863384A7 (fi
FI863384A0 (fi
Inventor
John J Baldwin
Gerald S Ponticello
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of FI863384A0 publication Critical patent/FI863384A0/fi
Publication of FI863384A7 publication Critical patent/FI863384A7/fi
Publication of FI863384L publication Critical patent/FI863384L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Luminescent Compositions (AREA)
  • Steroid Compounds (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Paper (AREA)
  • Detergent Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Catalysts (AREA)
FI863384A 1985-08-29 1986-08-21 Oculoselektiva -blockerare. FI863384L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/770,479 US4665094A (en) 1985-08-29 1985-08-29 Oculoselective beta-blockers for treatment of elevated intraocular pressure

Publications (3)

Publication Number Publication Date
FI863384A0 FI863384A0 (fi) 1986-08-21
FI863384A7 FI863384A7 (fi) 1987-03-01
FI863384L true FI863384L (fi) 1987-03-01

Family

ID=25088683

Family Applications (1)

Application Number Title Priority Date Filing Date
FI863384A FI863384L (fi) 1985-08-29 1986-08-21 Oculoselektiva -blockerare.

Country Status (18)

Country Link
US (1) US4665094A (de)
EP (1) EP0221788B1 (de)
JP (1) JPS6251649A (de)
KR (1) KR900003508B1 (de)
CN (1) CN86105229A (de)
AT (1) ATE53006T1 (de)
AU (1) AU6202686A (de)
CA (1) CA1286313C (de)
DE (1) DE3671429D1 (de)
DK (1) DK409186A (de)
ES (1) ES2002729A6 (de)
FI (1) FI863384L (de)
GR (1) GR862186B (de)
IL (1) IL79794A0 (de)
NO (1) NO863448L (de)
NZ (1) NZ217281A (de)
PT (1) PT83247B (de)
ZA (1) ZA866530B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5229127A (en) * 1989-03-03 1993-07-20 Mckinzie James W Rapid miosis with control of intraocular pressure using a mixture of a cetylcholine and carbachol derivatives
TW275614B (de) * 1993-02-15 1996-05-11 Senju Pharma Co
JPH0797373A (ja) * 1994-03-07 1995-04-11 Torcan Chem Ltd フェノールエーテルの製造のための環状中間体
CN103864653A (zh) * 2012-12-10 2014-06-18 韩冰 一类降低眼压的化合物及其用途

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes
US3541130A (en) * 1967-02-06 1970-11-17 Boehringer Sohn Ingelheim 1-(cyanophenoxy)-2-hydroxy-3-tert.-butylamine propanes
DE1593762A1 (de) * 1967-02-06 1972-06-08 Boehringer Sohn Ingelheim Verfahren zur Herstellung von neuen substituierten 1-Phenoxy-2-hydroxy-3-alkylaminopropanen
DE1643262C3 (de) * 1967-12-13 1975-06-26 C.H. Boehringer Sohn, 6507 Ingelheim i-Phenoxy^-hydroxy-S-alklyaminopropane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
SE358382B (de) * 1967-12-18 1973-07-30 Boehringer Sohn Ingelheim
GB1285038A (en) * 1969-02-21 1972-08-09 Ici Ltd Alkanolamine derivatives
DE1966513A1 (de) * 1969-08-19 1973-05-24 Boehringer Sohn Ingelheim 1-(3-hydroxymethyl-phenoxy)-2hydroxy-3-sek.-butylaminopropan, dessen saeureadditionssalze, verfahren zu deren herstellung und diese enthaltende praeparate
FR2119844B1 (de) * 1970-12-28 1974-03-22 Laroche Navarro Labo
JPS4911847A (de) * 1972-05-20 1974-02-01
SE386892B (sv) * 1972-07-06 1976-08-23 Haessle Ab Forfarande for framstellning av oxaminoforeningar
US4066768A (en) * 1973-12-27 1978-01-03 Cassella Farbwerke Mainkur Aktiengesellschaft Derivatives of 1-phenoxy-3-amino-propan-2-ol
DK405775A (da) * 1974-09-12 1976-03-13 American Cyanamid Co Fremgangsmade til fremstilling af alkanolaminer
DE2645710C2 (de) * 1976-10-09 1985-06-27 Merck Patent Gmbh, 6100 Darmstadt Phenoxy-amino-propanole, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitung
FI59985C (fi) * 1980-05-26 1982-01-08 Farmos Oy Foerfarande foer framstaellning av terapeutiskt aktiv 1-isopropylamino-3-(4-(2-metoxietyl)fenoxi)-2-propanol samt dess syra-additionssalter
FR2512443A1 (fr) * 1981-09-10 1983-03-11 Synthelabo Derives de phenoxy-3 propanol-2, leur preparation et leur application en therapeutique
DE3151201A1 (de) * 1981-12-23 1983-07-28 Beiersdorf Ag, 2000 Hamburg Substituierte phenoxyalkanolamine und phenoxyalkanol-cycloalkylamine, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische zubereitungen und zwischenprodukte
US4450172A (en) * 1982-03-10 1984-05-22 E. I. Du Pont De Nemours And Company Antihypertensive polyhalohydroxyisopropyl phenylalka(e)noic acid esters of alkylaminohydroxypropyloxyphenylalkyl alcohols
EP0105996A1 (de) * 1982-10-15 1984-04-25 Merck & Co. Inc. Ophthalmische Zusammensetzung für die Behandlung von erhöhtem intraokularen Druck

Also Published As

Publication number Publication date
KR870002050A (ko) 1987-03-28
DK409186A (da) 1987-03-01
NZ217281A (en) 1989-10-27
KR900003508B1 (ko) 1990-05-21
ATE53006T1 (de) 1990-06-15
IL79794A0 (en) 1986-11-30
NO863448D0 (no) 1986-08-28
ZA866530B (en) 1987-04-29
EP0221788A1 (de) 1987-05-13
CA1286313C (en) 1991-07-16
JPS6251649A (ja) 1987-03-06
GR862186B (en) 1986-12-23
AU6202686A (en) 1987-03-05
FI863384A7 (fi) 1987-03-01
CN86105229A (zh) 1987-04-22
ES2002729A6 (es) 1988-10-01
DK409186D0 (da) 1986-08-28
US4665094A (en) 1987-05-12
FI863384A0 (fi) 1986-08-21
PT83247B (pt) 1989-03-30
NO863448L (no) 1987-03-02
DE3671429D1 (de) 1990-06-28
EP0221788B1 (de) 1990-05-23
PT83247A (en) 1986-09-01

Similar Documents

Publication Publication Date Title
DE3681208D1 (de) Fluormeter.
ATE77088T1 (de) 8-phenylxanthine.
DE3677710D1 (de) Cefuroximaxetil-dragee.
DE3685611D1 (de) Polysiloxanelastomer.
ATE55980T1 (de) 2-hydroxy-3-phenoxypropylamine.
DE3668776D1 (de) Endotubus.
FI861273A0 (fi) Bildreduceringsteknik.
DE3668381D1 (de) Contactlinse.
DE3668885D1 (de) Fluorbenzylester.
DE3687867D1 (de) Mikrorechner.
FI83377B (fi) Mikrovaogsugn.
DE3669772D1 (de) Russblaeser.
FI863508A7 (fi) Flytvaest.
FI80864B (fi) Roerlig elevatortransportoer.
DE3688642D1 (de) Fdm-tdm-transmultiplexer.
DE3677472D1 (de) Blockierverhinderer.
NO862893D0 (no) Loeftesystem.
FI862132L (fi) Cytostatiskt verksamma titanocenkomplex.
DE3680574D1 (de) L-aminoacylasen.
DE3683724D1 (de) Zahnstutz.
DE3686729D1 (de) Aminoalkylpyridinamide.
DE3673520D1 (de) Perfluorpolyaether.
FI73923B (fi) Polyamidhaltig maongskiktsfilm.
DE3670979D1 (de) Raederfalzapparat.
EP0217961A4 (de) Mottenschutz.

Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: MERCK & CO., INC.