FI863776L - Foerfarande foer framstaellning av 7-aminomitosanderivat. - Google Patents

Foerfarande foer framstaellning av 7-aminomitosanderivat. Download PDF

Info

Publication number
FI863776L
FI863776L FI863776A FI863776A FI863776L FI 863776 L FI863776 L FI 863776L FI 863776 A FI863776 A FI 863776A FI 863776 A FI863776 A FI 863776A FI 863776 L FI863776 L FI 863776L
Authority
FI
Finland
Prior art keywords
aminomitosander
rivers
foerfarande foer
foer framstaellning
framstaellning
Prior art date
Application number
FI863776A
Other languages
English (en)
Finnish (fi)
Other versions
FI863776A0 (fi
FI863776A7 (fi
Inventor
Dolatrai Mohanlal Vyas
Yulin Chiang
Terrence William Doyle
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI863776A0 publication Critical patent/FI863776A0/fi
Publication of FI863776L publication Critical patent/FI863776L/fi
Publication of FI863776A7 publication Critical patent/FI863776A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI863776A 1985-09-23 1986-09-18 Menetelmä 7-aminomitosaanijohdannaisten valmistamiseksi. FI863776A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/781,076 US4866180A (en) 1984-02-24 1985-09-23 Amino disulfide thiol exchange products

Publications (3)

Publication Number Publication Date
FI863776A0 FI863776A0 (fi) 1986-09-18
FI863776L true FI863776L (fi) 1987-03-24
FI863776A7 FI863776A7 (fi) 1987-03-24

Family

ID=25121607

Family Applications (1)

Application Number Title Priority Date Filing Date
FI863776A FI863776A7 (fi) 1985-09-23 1986-09-18 Menetelmä 7-aminomitosaanijohdannaisten valmistamiseksi.

Country Status (10)

Country Link
US (1) US4866180A (fr)
KR (1) KR940006629B1 (fr)
AT (1) AT394725B (fr)
CA (1) CA1288106C (fr)
ES (1) ES2001978A6 (fr)
FI (1) FI863776A7 (fr)
GR (1) GR862416B (fr)
LU (1) LU86600A1 (fr)
PT (1) PT83418B (fr)
ZA (1) ZA866297B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5175303A (en) * 1990-03-08 1992-12-29 Bristol-Myers Squibb Company Preparation of 7-(diphenylmethyl)oxy-9A-methoxymitosane
US5629427A (en) * 1993-08-26 1997-05-13 Peterson; Dwight M. 2,7-diaminomitosene analogues
EP1389209B1 (fr) * 2001-04-24 2009-04-08 Purdue Research Foundation Mimetiques de folate et ses conjugues se liant au recepteur de folate
WO2003097647A1 (fr) * 2002-05-15 2003-11-27 Endocyte, Inc. Conjugues vitamine-mitomycine
DK1592457T3 (da) 2003-01-27 2012-10-22 Endocyte Inc Folat-vinblastin-konjugat som lægemiddel
JP5149620B2 (ja) 2004-07-23 2013-02-20 エンドサイト，インコーポレイテッド ２価リンカーおよびその結合体
EP1863816B1 (fr) * 2005-03-16 2014-06-25 Endocyte, Inc. Synthese et purification d'acide pteroique et des conjugues de celui-ci
EP2382995A3 (fr) * 2005-08-19 2013-09-25 Endocyte, Inc. Conjugués de ligands d'alcaloïdes de Vinca, analogues et dérivés
AU2006279304A1 (en) * 2005-08-19 2007-02-22 Endocyte, Inc. Multi-drug ligand conjugates
WO2008101231A2 (fr) 2007-02-16 2008-08-21 Endocyte, Inc. Procédés et compositions de traitement et de diagnostic d'une maladie rénale
CN104127878A (zh) * 2007-03-14 2014-11-05 恩多塞特公司 结合配体连接的微管溶素递药缀合物
US9877965B2 (en) 2007-06-25 2018-01-30 Endocyte, Inc. Vitamin receptor drug delivery conjugates for treating inflammation
BRPI0812970A2 (pt) * 2007-06-25 2019-09-24 Endocyte Inc conjugados contendo espaçadores hidrofílicos
US9187521B2 (en) * 2007-10-25 2015-11-17 Endocyte, Inc. Tubulysins and processes for preparing
US10080805B2 (en) 2012-02-24 2018-09-25 Purdue Research Foundation Cholecystokinin B receptor targeting for imaging and therapy
US20140080175A1 (en) 2012-03-29 2014-03-20 Endocyte, Inc. Processes for preparing tubulysin derivatives and conjugates thereof
EP2908818A4 (fr) 2012-10-16 2016-07-13 Endocyte Inc Conjugués d'administration de médicament contenant des acides aminés artificiels et procédés d'utilisation

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3660578A (en) * 1957-04-06 1972-05-02 Kyowa Hakko Kogyo Kk Mitomycin c
NL129868C (fr) * 1963-06-07
DE1570029A1 (de) * 1964-07-09 1970-04-09 Kyowa Hakko Kogyo Kk Verfahren zur Herstellung von Mitosanverbindungen
US3420846A (en) * 1964-08-25 1969-01-07 Kyowa Hakko Kogyo Kk 7-substituted mitomycin a
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
GB2093643A (en) * 1981-02-17 1982-09-02 Standard Telephones Cables Ltd DC-to-DC converter
EP0116208B1 (fr) * 1982-12-07 1988-03-30 Kyowa Hakko Kogyo Co., Ltd. Analogues de mitomycine
US4803212A (en) * 1983-04-11 1989-02-07 Bristol-Myers Company Amino disulfides
JPS60255789A (ja) * 1984-06-01 1985-12-17 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体，その製造法および抗腫瘍剤

Also Published As

Publication number Publication date
PT83418B (pt) 1989-05-12
US4866180A (en) 1989-09-12
ES2001978A6 (es) 1988-07-01
LU86600A1 (fr) 1987-04-02
KR940006629B1 (ko) 1994-07-23
KR870003111A (ko) 1987-04-15
FI863776A0 (fi) 1986-09-18
FI863776A7 (fi) 1987-03-24
ATA254886A (de) 1991-11-15
AT394725B (de) 1992-06-10
PT83418A (en) 1986-10-01
CA1288106C (fr) 1991-08-27
ZA866297B (en) 1987-04-29
GR862416B (en) 1987-01-26

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: BRISTOL-MYERS CO