FI922013A7 - Förfarande för framställning av terapeutiskt användbara 3-kinuklidinylbutanoater och -propanoater samt mellanprodukter - Google Patents

Förfarande för framställning av terapeutiskt användbara 3-kinuklidinylbutanoater och -propanoater samt mellanprodukter

Info

Publication number: FI922013A7
Authority: FI; Finland
Prior art keywords: propanoates; butanoates; quinuclidinyl; intermediates; preparation
Prior art date: 1990-09-06

Application number

FI922013A

Other languages

English (en)

Finnish (fi)

Other versions

FI922013A0 (sv

FI97469C (sv

FI97469B (sv

Inventor

Alan Stobie

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-09-06

Filing date

1992-05-05

Publication date

1992-05-05

1990-09-06 Priority claimed from GB909019472A external-priority patent/GB9019472D0/en

1991-03-28 Priority claimed from GB919106733A external-priority patent/GB9106733D0/en

1992-05-05 Application filed by Pfizer filed Critical Pfizer

1992-05-05 Publication of FI922013A0 publication Critical patent/FI922013A0/sv

1992-05-05 Publication of FI922013A7 publication Critical patent/FI922013A7/sv

1996-09-13 Application granted granted Critical

1996-09-13 Publication of FI97469B publication Critical patent/FI97469B/sv

1996-12-27 Publication of FI97469C publication Critical patent/FI97469C/sv

Links

BJNCVECKNVBHBP-UHFFFAOYSA-N 1-azabicyclo[2.2.2]octan-3-yl butanoate Chemical class C1CC2C(OC(=O)CCC)CN1CC2 BJNCVECKNVBHBP-UHFFFAOYSA-N 0.000 title 1
XBDQKXXYIPTUBI-UHFFFAOYSA-N Propionic acid Chemical class CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 title 1
239000000543 intermediate Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicinal Preparation (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

FI922013A 1990-09-06 1992-05-05 Förfarande för framställning av terapeutiskt användbara 3-kinuklidinylbutanoater och -propanoater samt mellanprodukter FI97469C (sv)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
GB909019472A GB9019472D0 (en)	1990-09-06	1990-09-06	Antimuscarinic bronchodilators
GB9019472		1990-09-06
GB9106733		1991-03-28
GB919106733A GB9106733D0 (en)	1991-03-28	1991-03-28	Antimuscarinic bronchodilators
EP9101670		1991-09-03
PCT/EP1991/001670 WO1992004346A1 (en)	1990-09-06	1991-09-03	Antimuscarinic bronchodilators

Publications (4)

Publication Number	Publication Date
FI922013A0 FI922013A0 (sv)	1992-05-05
FI922013A7 true FI922013A7 (sv)	1992-05-05
FI97469B FI97469B (sv)	1996-09-13
FI97469C FI97469C (sv)	1996-12-27

Family

ID=26297607

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI922013A FI97469C (sv)	1990-09-06	1992-05-05	Förfarande för framställning av terapeutiskt användbara 3-kinuklidinylbutanoater och -propanoater samt mellanprodukter

Country Status (12)

Country	Link
US (1)	US5292749A (sv)
EP (1)	EP0500864B1 (sv)
JP (1)	JPH0725756B2 (sv)
AT (1)	ATE205844T1 (sv)
CA (1)	CA2073005C (sv)
DE (1)	DE69132735T2 (sv)
DK (1)	DK0500864T3 (sv)
ES (1)	ES2161211T3 (sv)
FI (1)	FI97469C (sv)
IE (1)	IE913119A1 (sv)
PT (1)	PT98858B (sv)
WO (1)	WO1992004346A1 (sv)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5264415A (en) *	1992-06-25	1993-11-23	Rohm And Haas Company	Fungicidal and herbicidal triazoles
US5981549A (en) *	1997-02-14	1999-11-09	Synapse Pharmaceutical International	Method for controlling or alleviating the symptoms of respiratory disease and allergies
US20020098109A1 (en) *	1997-09-17	2002-07-25	Jerry Nelson	Method and apparatus for producing purified or ozone enriched air to remove contaminants from fluids
ES2165768B1 (es)	1999-07-14	2003-04-01	Almirall Prodesfarma Sa	Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
WO2002053564A2 (en) *	2000-12-28	2002-07-11	Almirall Prodesfarma Ag	Quinuclidine derivatives and their use as m3 antagonists
AU2003269380A1 (en) *	2002-10-29	2004-05-25	Pharmacia & Upjohn Company Llc	Quinuclidinium derivatives as antimuscarinic agents
EP1781617A4 (en) *	2004-06-30	2009-06-24	Janssen Pharmaceutica Nv	ESTERS AND ACIDS ALPHA, BETA-UNSATURATED BY STEREOSELECTIVE DEHYDRATION
EP2100599A1 (en)	2008-03-13	2009-09-16	Laboratorios Almirall, S.A.	Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100598A1 (en)	2008-03-13	2009-09-16	Laboratorios Almirall, S.A.	Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2510928A1 (en)	2011-04-15	2012-10-17	Almirall, S.A.	Aclidinium for use in improving the quality of sleep in respiratory patients
WO2013134562A1 (en)	2012-03-09	2013-09-12	Inception 2, Inc.	Triazolone compounds and uses thereof
CA2894281C (en)	2012-12-20	2021-04-20	Inception 2, Inc.	Triazolone compounds and uses thereof
EP3041826A4 (en)	2013-09-06	2017-02-15	Inception 2, Inc.	Triazolone compounds and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3290316A (en) *	1962-08-03	1966-12-06	Hoffmann La Roche	Alpha-3-pyridylmandelic acid and derivatives thereof
US3833592A (en) *	1966-05-31	1974-09-03	Little Inc A	Tropanyl alpha,alpha-diphenyl-alpha-fluoroacetate esters
GB1219606A (en) *	1968-07-15	1971-01-20	Rech S Et D Applic Scient Soge	Quinuclidinol derivatives and preparation thereof
US4431627A (en) *	1980-06-03	1984-02-14	Research Corporation	Gamma-emitting receptor-binding 3-quinuclidinyl glycolates; methods of preparation thereof and imaging and assay methods utilizing same
US4644003A (en) *	1985-04-03	1987-02-17	Research Corporation	3-quinuclidinol esters, useful as antagonists of muscarinic acetylcholine receptors
US4843074A (en) *	1988-05-17	1989-06-27	Marion Laboratories, Inc.	1-azabicyclo[2.2.2]octan-3-yl 2-aryl-3-azacyclo-2-hydroxypropionates and their quaternary salts
DE58906678D1 (de) *	1988-07-28	1994-02-24	Ciba Geigy	Kupfer- und Nickeldihalogenidkomplexe, Verfahren zu deren Herstellung und deren Verwendung.
IT1228288B (it) *	1989-01-09	1991-06-07	Zambon Spa	Composti ad attivita' antiserotoninica
GB8923590D0 (en) *	1989-10-19	1989-12-06	Pfizer Ltd	Antimuscarinic bronchodilators

1991
- 1991-09-03 CA CA002073005A patent/CA2073005C/en not_active Expired - Fee Related
- 1991-09-03 JP JP3513922A patent/JPH0725756B2/ja not_active Expired - Fee Related
- 1991-09-03 DE DE69132735T patent/DE69132735T2/de not_active Expired - Fee Related
- 1991-09-03 AT AT91915623T patent/ATE205844T1/de not_active IP Right Cessation
- 1991-09-03 EP EP91915623A patent/EP0500864B1/en not_active Expired - Lifetime
- 1991-09-03 WO PCT/EP1991/001670 patent/WO1992004346A1/en not_active Ceased
- 1991-09-03 ES ES91915623T patent/ES2161211T3/es not_active Expired - Lifetime
- 1991-09-03 DK DK91915623T patent/DK0500864T3/da active
- 1991-09-04 PT PT98858A patent/PT98858B/pt not_active IP Right Cessation
- 1991-09-05 IE IE311991A patent/IE913119A1/en not_active Application Discontinuation
1992
- 1992-05-05 FI FI922013A patent/FI97469C/sv active
- 1992-06-05 US US07/852,261 patent/US5292749A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE69132735T2 (de)	2002-05-29
PT98858A (pt)	1992-07-31
ATE205844T1 (de)	2001-10-15
FI922013A0 (sv)	1992-05-05
DK0500864T3 (da)	2001-11-12
CA2073005A1 (en)	1992-03-07
PT98858B (pt)	1999-07-30
DE69132735D1 (de)	2001-10-25
JPH05502454A (ja)	1993-04-28
EP0500864B1 (en)	2001-09-19
IE913119A1 (en)	1992-03-11
JPH0725756B2 (ja)	1995-03-22
ES2161211T3 (es)	2001-12-01
US5292749A (en)	1994-03-08
CA2073005C (en)	1998-11-10
FI97469C (sv)	1996-12-27
FI97469B (sv)	1996-09-13
EP0500864A1 (en)	1992-09-02
WO1992004346A1 (en)	1992-03-19

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Legal Events

Date	Code	Title	Description
1996-08-21	BB	Publication of examined application