FI960663L - DNA-sekvenssi, joka koodaa A. thaliana -proteiinia, jolla on delta-5,7-steroli, delta-7-reduktaasiaktiivisuutta, delta-7-Red-proteiinia, menetelmä sen valmistamiseksi, muunnettuja hiivakantoja sekä sovellutuksia - Google Patents

DNA-sekvenssi, joka koodaa A. thaliana -proteiinia, jolla on delta-5,7-steroli, delta-7-reduktaasiaktiivisuutta, delta-7-Red-proteiinia, menetelmä sen valmistamiseksi, muunnettuja hiivakantoja sekä sovellutuksia Download PDF

Info

Publication number
FI960663L
FI960663L FI960663A FI960663A FI960663L FI 960663 L FI960663 L FI 960663L FI 960663 A FI960663 A FI 960663A FI 960663 A FI960663 A FI 960663A FI 960663 L FI960663 L FI 960663L
Authority
FI
Finland
Prior art keywords
delta
protein
sterol
applications
preparation
Prior art date
Application number
FI960663A
Other languages
English (en)
Swedish (sv)
Other versions
FI960663A0 (fi
FI120877B (fi
Inventor
Xavier Chenivesse
Catherine Duport
Eric Lecain
Denis Pompon
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9501723A external-priority patent/FR2730494B1/fr
Priority claimed from FR9506517A external-priority patent/FR2734839B1/fr
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of FI960663A0 publication Critical patent/FI960663A0/fi
Publication of FI960663L publication Critical patent/FI960663L/fi
Application granted granted Critical
Publication of FI120877B publication Critical patent/FI120877B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/02—Dehydrogenating; Dehydroxylating

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FI960663A 1995-02-15 1996-02-14 DNA-sekvenssi, joka koodaa A. thaliana -proteiinia, jolla on delta-5,7-steroli, delta-7-reduktaasiaktiivisuutta, delta-7-Red-proteiinia, menetelmä sen valmistamiseksi, muunnettuja hiivakantoja sekä sovellutuksia FI120877B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9501723 1995-02-15
FR9501723A FR2730494B1 (fr) 1995-02-15 1995-02-15 Sequence d'adn codant pour une proteine d'a. thaliana ayant une activite delta-5,7 sterol, delta-7 reductase, proteine delta7-red, procede de production, souches de levures transformees, applications
FR9506517 1995-06-01
FR9506517A FR2734839B1 (fr) 1995-06-01 1995-06-01 Sequence d'adn codant pour une proteine d'a. thaliana ayant une activite delta-5,7 sterol, delta-7 reductase, proteine delta-7red, procede de production, souches de levures transformees, applications.

Publications (3)

Publication Number Publication Date
FI960663A0 FI960663A0 (fi) 1996-02-14
FI960663L true FI960663L (fi) 1996-08-16
FI120877B FI120877B (fi) 2010-04-15

Family

ID=26231759

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960663A FI120877B (fi) 1995-02-15 1996-02-14 DNA-sekvenssi, joka koodaa A. thaliana -proteiinia, jolla on delta-5,7-steroli, delta-7-reduktaasiaktiivisuutta, delta-7-Red-proteiinia, menetelmä sen valmistamiseksi, muunnettuja hiivakantoja sekä sovellutuksia

Country Status (24)

Country Link
US (3) US5759801A (fi)
EP (1) EP0727489B1 (fi)
JP (1) JP4082469B2 (fi)
KR (1) KR100422293B1 (fi)
CN (2) CN1664107A (fi)
AR (2) AR003407A1 (fi)
AT (1) ATE457354T1 (fi)
BR (1) BRPI9600729B8 (fi)
CA (1) CA2169524C (fi)
CZ (1) CZ294860B6 (fi)
DE (1) DE69638123D1 (fi)
DK (1) DK0727489T3 (fi)
ES (1) ES2339833T3 (fi)
FI (1) FI120877B (fi)
HR (1) HRP960078B1 (fi)
HU (1) HU220587B1 (fi)
IL (4) IL162476A (fi)
PL (1) PL185569B1 (fi)
PT (1) PT727489E (fi)
RU (1) RU2242517C2 (fi)
SI (1) SI0727489T1 (fi)
SK (1) SK283656B6 (fi)
TR (1) TR199600116A2 (fi)
UA (1) UA72172C2 (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997048793A1 (en) * 1996-06-21 1997-12-24 The General Hospital Corporation Plant sterol reductases and uses thereof
DE19739940A1 (de) * 1997-09-11 1999-03-18 Hartmut Prof Dr Med Glossmann Protein mit Aminosäuresequenz der DELTA7-Sterolreduktase, isoliertes cDNA-Molekül, das für das Protein kodiert, rekombinanter DNA-Vektor und biologisch aktive Zusammensetzungen, die das Protein oder das cDNA-Molekül enthalten
FR2774393B1 (fr) * 1998-02-05 2000-03-24 Hoechst Marion Roussel Inc Souches de levure ayant le gene atf2 interrompu et leurs applications
US6465717B1 (en) * 1998-11-20 2002-10-15 E. I. Du Pont De Nemours And Company Sterol metabolism enzymes
FR2812884B1 (fr) * 2000-08-08 2002-11-08 Aventis Pharma Sa Levures modifiees et utilisations, notamment pour la production de derives steroidiens
FR2820145B1 (fr) * 2001-01-31 2004-01-23 Aventis Pharma Sa Souche de levure produisant des steroides de facon autonome
US7193169B2 (en) * 2003-10-29 2007-03-20 Alcon, Inc. Ergonomic footswitch
FR2869914B1 (fr) 2004-05-06 2012-11-09 Aventis Pharma Sa Souches de levure produisant du cholesterol et leurs applications
CA2600882C (en) * 2005-03-16 2013-02-26 Metabolix, Inc. Chemically inducible expression of biosynthetic pathways
KR100672006B1 (ko) * 2005-08-03 2007-01-19 길병옥 폐자재를 이용한 형강의 제조방법 및 그 제조방법에 의해생산된 형강
JP5660900B2 (ja) * 2007-12-21 2015-01-28 ノバルティス アーゲー 有機化合物
DE102009022772A1 (de) 2009-05-21 2010-11-25 Organobalance Gmbh Mikroorganismus zur Expression eines humanen Membranproteins
FR2961218A1 (fr) * 2010-06-10 2011-12-16 Sanofi Aventis Methode de detection de composes modulateurs du metabolisme du cholesterol
CN102286053B (zh) * 2011-06-20 2012-09-05 河北联合大学 孕甾烯醇酮吡咯化合物及其制备方法
CN118109544A (zh) 2013-06-17 2024-05-31 赛诺菲 用于细胞色素p450单加氧酶生物催化的全细胞系统
CN110903993A (zh) * 2019-12-20 2020-03-24 河北兰升生物科技有限公司 一种产生菜籽甾醇的酿酒酵母工程菌及其构建方法和应用
CN112813129B (zh) * 2021-02-05 2023-09-08 江南大学 利用区室化提高酵母菌中7-脱氢胆固醇产量的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2554986A (en) * 1950-01-05 1951-05-29 Upjohn Co Synthesis of pregnenolone
JPS6447380A (en) * 1987-08-19 1989-02-21 Agency Ind Science Techn Steroid-oxidizing yeast strain
CN1042567A (zh) * 1988-09-23 1990-05-30 吉斯特-布罗卡迪斯公司 类固醇多步氧化方法和所用的遗传工程细胞
JP2645130B2 (ja) * 1989-03-31 1997-08-25 日清製粉株式会社 ステロイド誘導体
US5212167A (en) * 1991-09-12 1993-05-18 Trustees Of Boston University Modulation of receptor-mediated ion transport
US5547868A (en) * 1993-06-09 1996-08-20 Regents Of The University Of California Cholesterol disposal fusion enzymes

Also Published As

Publication number Publication date
ATE457354T1 (de) 2010-02-15
TR199600116A2 (tr) 1996-08-21
DK0727489T3 (da) 2010-05-31
PL312828A1 (en) 1996-08-19
FI960663A0 (fi) 1996-02-14
SK18896A3 (en) 1996-10-02
US5965417A (en) 1999-10-12
PL185569B1 (pl) 2003-06-30
SK283656B6 (sk) 2003-11-04
BRPI9600729A (pt) 1997-12-23
HU220587B1 (hu) 2002-03-28
IL116872A (en) 2004-12-15
AR003407A1 (es) 1998-08-05
BRPI9600729B8 (pt) 2021-07-06
HRP960078B1 (en) 2011-11-30
HUP9600325A3 (en) 1999-07-28
CN1216995C (zh) 2005-08-31
PT727489E (pt) 2010-04-27
DE69638123D1 (de) 2010-03-25
CZ43296A3 (en) 1996-12-11
JP4082469B2 (ja) 2008-04-30
KR960031607A (ko) 1996-09-17
CA2169524C (fr) 2012-05-01
FI120877B (fi) 2010-04-15
JPH08289793A (ja) 1996-11-05
UA72172C2 (uk) 2005-02-15
EP0727489B1 (fr) 2010-02-10
CN1664107A (zh) 2005-09-07
CA2169524A1 (fr) 1996-08-16
KR100422293B1 (ko) 2004-06-14
HUP9600325A1 (en) 1996-11-28
AR053931A2 (es) 2007-05-23
ES2339833T3 (es) 2010-05-25
IL162477A0 (en) 2005-11-20
US5989881A (en) 1999-11-23
BRPI9600729B1 (pt) 2017-06-20
SI0727489T1 (sl) 2010-05-31
US5759801A (en) 1998-06-02
IL162476A0 (en) 2005-11-20
IL116872A0 (en) 1996-07-23
EP0727489A1 (fr) 1996-08-21
RU2242517C2 (ru) 2004-12-20
HRP960078A2 (fi) 1998-02-28
CN1145953A (zh) 1997-03-26
IL162476A (en) 2005-12-18
CZ294860B6 (cs) 2005-04-13

Similar Documents

Publication Publication Date Title
FI960663L (fi) DNA-sekvenssi, joka koodaa A. thaliana -proteiinia, jolla on delta-5,7-steroli, delta-7-reduktaasiaktiivisuutta, delta-7-Red-proteiinia, menetelmä sen valmistamiseksi, muunnettuja hiivakantoja sekä sovellutuksia
AU5782900A (en) Secure, limited-access database system and method
AU3379297A (en) Computer system architecture and method for multi-user, real-time applications
KR970002039A (ko) 급속발효 사료와 그 제조방법 및 용도
AU693663B2 (en) Biochemical information processor, biochemical information processing method, and biochemical information recording medium
AU7029498A (en) Deformation element, method for its production and its use
AU5800696A (en) Rhesus ob protein and dna
AU5906699A (en) (neisseria spp.) polypeptide, nucleic acid sequence and uses thereof
AU8620698A (en) Antifreeze proteins, dna and expression systems
EP0671470A3 (en) Enzyme releasing trehalose, DNA coding for it, their preparation and use.
AU6978096A (en) Dna encoding an sh2-inositol phosphatase, an shc-binding protein
AU1137699A (en) Novel reovirus-derived proteins, nucleic acids encoding same, and uses therefor
AU5137698A (en) Novel dna, novel protein, and novel antibody
AU2001242824A1 (en) Individual body identifying method by two-dimensional code, hybrid individual person authenticating system, and off-line person identifying system
AU5545896A (en) H. Influenzae HxuB and HxuC genes, proteins and methods of use
AU1693995A (en) Phosphacan, nucleic acids encoding thereof and antibodies thereto
FR2734839B1 (fr) Sequence d'adn codant pour une proteine d'a. thaliana ayant une activite delta-5,7 sterol, delta-7 reductase, proteine delta-7red, procede de production, souches de levures transformees, applications.
WO1999001475A3 (de) Humaner antikörper gegen ein fusions(poly)peptid bzw. -protein, das einen anteil von mindestens sechs histidinen aufweist
WO2001000799A8 (fr) Nouvelle proteine et son adn
ATE309371T1 (de) Protein mit dnase-aktivität
AU3526200A (en) Generation of conditional yeast mutants, methods and reagents related thereto
AU7109698A (en) A nitrobenzylmercaptopurineriboside (nbmpr)-insensitive, equilibrative, nucleoside transport protein, nucleic acids encoding the same and methods of use
AU6129196A (en) deltaP62, its variants, nucleic acid sequences and their uses
AU7478098A (en) Methods of treatment using nbs-1, antibodies and proteins thereto, and uses of the antibodies
FR2730494B1 (fr) Sequence d'adn codant pour une proteine d'a. thaliana ayant une activite delta-5,7 sterol, delta-7 reductase, proteine delta7-red, procede de production, souches de levures transformees, applications

Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: HOECHST MARION ROUSSEL

FG Patent granted

Ref document number: 120877

Country of ref document: FI

MA Patent expired