FI962019L - Pyrone derivatives as protease inhibitors and antiviral agents - Google Patents
Pyrone derivatives as protease inhibitors and antiviral agents Download PDFInfo
- Publication number
- FI962019L FI962019L FI962019A FI962019A FI962019L FI 962019 L FI962019 L FI 962019L FI 962019 A FI962019 A FI 962019A FI 962019 A FI962019 A FI 962019A FI 962019 L FI962019 L FI 962019L
- Authority
- FI
- Finland
- Prior art keywords
- protease inhibitors
- antiviral agents
- pyrone derivatives
- pyrone
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Chemical Vapour Deposition (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15502893A | 1993-11-19 | 1993-11-19 | |
| US08/319,768 US5808062A (en) | 1993-11-19 | 1994-10-12 | Pyrone derivatives as protease inhibitors and antiviral agents |
| PCT/US1994/012367 WO1995014014A2 (en) | 1993-11-19 | 1994-10-26 | Pyrone derivatives as protease inhibitors and antiviral agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI962019A0 FI962019A0 (en) | 1996-05-13 |
| FI962019L true FI962019L (en) | 1996-05-20 |
| FI962019A7 FI962019A7 (en) | 1996-05-20 |
Family
ID=26851948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI962019A FI962019A7 (en) | 1993-11-19 | 1994-10-26 | Pyrone derivatives as protease inhibitors and antiviral agents a |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0729466A1 (en) |
| JP (1) | JPH09505295A (en) |
| AU (1) | AU682417B2 (en) |
| BG (1) | BG62770B1 (en) |
| CA (1) | CA2174124A1 (en) |
| CZ (1) | CZ134396A3 (en) |
| EE (1) | EE9600044A (en) |
| FI (1) | FI962019A7 (en) |
| HR (1) | HRP940938A2 (en) |
| HU (1) | HUT74888A (en) |
| IL (1) | IL111671A0 (en) |
| NO (1) | NO962015L (en) |
| PL (1) | PL314484A1 (en) |
| RU (1) | RU2153497C2 (en) |
| SK (1) | SK63996A3 (en) |
| WO (1) | WO1995014014A2 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW587079B (en) * | 1998-09-25 | 2004-05-11 | Almirall Prodesfarma Ag | 2-phenylpyran-4-one derivatives |
| ES2168895A1 (en) * | 1999-03-26 | 2002-06-16 | Almirall Prodesfarma Sa | 2-Phenylpyran-4-one derivatives as cyclooxygenase-2 (COX-2) inhibitors useful e.g. for treating pain, fever or inflammation, preventing colorectal cancer or neurodegenerative diseases |
| ES2154561B1 (en) * | 1998-09-25 | 2001-12-01 | Almirall Prodesfarma Sa | DERIVATIVES OF 2-FENILPIRAN-4-ONA. |
| PE20011333A1 (en) * | 2000-03-16 | 2002-01-16 | Almirall Prodesfarma Ag | DERIVATIVES OF 2-FENYLPYRAN-4-ONA AS INHIBITORS OF CYCLOOXYGENASE 2 |
| KR102384668B1 (en) * | 2016-06-14 | 2022-04-07 | 브리스톨-마이어스 스큅 컴퍼니 | 6-hydroxy-5-(phenyl/heteroarylsulfonyl)pyrimidin-4(1H)-one as APJ agonist |
| JP6962941B2 (en) * | 2016-06-14 | 2021-11-05 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | 4-Hydroxy-3-sulfonylpyridin-2 (1H) -one as an APJ receptor agonist |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR3724M (en) * | 1963-12-04 | 1965-12-06 | Marcel Perrault | Medicinal product based on anisoyl-3 hydroxy-4 p. methoxy-phenyl-6α-pyrone. |
| US3818046A (en) * | 1972-12-18 | 1974-06-18 | Dow Chemical Co | Sulfur-containing hydroxy pyrones and alkali metal salts thereof |
| DE4308451A1 (en) * | 1992-09-10 | 1994-04-14 | Bayer Ag | 3-aryl-pyrone derivatives |
| ZA938019B (en) * | 1992-11-13 | 1995-04-28 | Upjohn Co | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses |
| JP3372338B2 (en) * | 1994-02-14 | 2003-02-04 | オリンパス光学工業株式会社 | Distance measuring device |
-
1994
- 1994-10-26 FI FI962019A patent/FI962019A7/en unknown
- 1994-10-26 AU AU81276/94A patent/AU682417B2/en not_active Ceased
- 1994-10-26 RU RU96113056/04A patent/RU2153497C2/en active
- 1994-10-26 PL PL94314484A patent/PL314484A1/en unknown
- 1994-10-26 SK SK639-96A patent/SK63996A3/en unknown
- 1994-10-26 EE EE9600044A patent/EE9600044A/en unknown
- 1994-10-26 CA CA002174124A patent/CA2174124A1/en not_active Abandoned
- 1994-10-26 JP JP7514461A patent/JPH09505295A/en active Pending
- 1994-10-26 WO PCT/US1994/012367 patent/WO1995014014A2/en not_active Ceased
- 1994-10-26 EP EP95900457A patent/EP0729466A1/en not_active Withdrawn
- 1994-10-26 CZ CZ961343A patent/CZ134396A3/en unknown
- 1994-10-26 HU HU9601347A patent/HUT74888A/en unknown
- 1994-11-17 IL IL11167194A patent/IL111671A0/en unknown
- 1994-11-18 HR HR08/319,768A patent/HRP940938A2/en not_active Application Discontinuation
-
1996
- 1996-05-03 BG BG100564A patent/BG62770B1/en unknown
- 1996-05-15 NO NO962015A patent/NO962015L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0729466A1 (en) | 1996-09-04 |
| CA2174124A1 (en) | 1995-05-26 |
| EE9600044A (en) | 1996-10-15 |
| SK63996A3 (en) | 1996-11-06 |
| WO1995014014A3 (en) | 1995-06-15 |
| JPH09505295A (en) | 1997-05-27 |
| AU682417B2 (en) | 1997-10-02 |
| HU9601347D0 (en) | 1996-07-29 |
| IL111671A0 (en) | 1995-01-24 |
| AU8127694A (en) | 1995-06-06 |
| BG100564A (en) | 1996-12-31 |
| NO962015D0 (en) | 1996-05-15 |
| RU2153497C2 (en) | 2000-07-27 |
| HRP940938A2 (en) | 1997-06-30 |
| BG62770B1 (en) | 2000-07-31 |
| PL314484A1 (en) | 1996-09-16 |
| FI962019A7 (en) | 1996-05-20 |
| WO1995014014A2 (en) | 1995-05-26 |
| HUT74888A (en) | 1997-02-28 |
| NO962015L (en) | 1996-05-15 |
| CZ134396A3 (en) | 1996-08-14 |
| FI962019A0 (en) | 1996-05-13 |
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