FI990596L - Luun morfogeneettiset proteiini-16 (BMP-16) -koostumukset - Google Patents

Luun morfogeneettiset proteiini-16 (BMP-16) -koostumukset Download PDF

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Publication number
FI990596L
FI990596L FI990596A FI990596A FI990596L FI 990596 L FI990596 L FI 990596L FI 990596 A FI990596 A FI 990596A FI 990596 A FI990596 A FI 990596A FI 990596 L FI990596 L FI 990596L
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FI
Finland
Prior art keywords
bmp
formulations
bone morphogenetic
morphogenetic protein
protein
Prior art date
Application number
FI990596A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI990596A7 (fi
FI990596A0 (fi
Inventor
Anthony J Celeste
Beth L Murray
Original Assignee
Genetics Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst filed Critical Genetics Inst
Publication of FI990596A7 publication Critical patent/FI990596A7/fi
Publication of FI990596A0 publication Critical patent/FI990596A0/fi
Publication of FI990596L publication Critical patent/FI990596L/fi

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI990596A 1996-09-18 1997-07-09 Luun morfogeneettiset proteiini-16 (BMP-16) -koostumukset FI990596L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/715,202 US5965403A (en) 1996-09-18 1996-09-18 Nucleic acids encoding bone morphogenic protein-16 (BMP-16)
PCT/US1997/011954 WO1998012322A1 (en) 1996-09-18 1997-07-09 Bone morphogenetic protein-16 (bmp-16) compositions

Publications (3)

Publication Number Publication Date
FI990596A7 FI990596A7 (fi) 1999-03-17
FI990596A0 FI990596A0 (fi) 1999-03-17
FI990596L true FI990596L (fi) 1999-05-03

Family

ID=24873057

Family Applications (1)

Application Number Title Priority Date Filing Date
FI990596A FI990596L (fi) 1996-09-18 1997-07-09 Luun morfogeneettiset proteiini-16 (BMP-16) -koostumukset

Country Status (9)

Country Link
US (3) US5965403A (de)
EP (1) EP0941323A1 (de)
JP (1) JP2001500737A (de)
KR (1) KR20000036012A (de)
CA (1) CA2265508C (de)
FI (1) FI990596L (de)
NO (1) NO991271D0 (de)
OA (1) OA10997A (de)
WO (1) WO1998012322A1 (de)

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US6150328A (en) 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
DE69233022T2 (de) 1991-11-04 2004-02-12 Genetics Institute, LLC, Cambridge Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
DE69434651T2 (de) 1993-12-07 2007-03-08 Genetics Institute, Inc., Cambridge Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen
US8106001B2 (en) * 1996-08-27 2012-01-31 University Of South Florida Diagnostic markers of human female infertility
US5965403A (en) * 1996-09-18 1999-10-12 Genetics Institute, Inc. Nucleic acids encoding bone morphogenic protein-16 (BMP-16)
EP0954580B1 (de) * 1997-02-06 2003-12-17 Genetics Institute, LLC Menschliches sdf-5 protein und diesbezügliche zusammensetzungen
EP1001964A4 (de) * 1997-08-04 2003-04-23 Millennium Pharm Inc Tango-78, tango-79 und tango-81 nukleinsäuremoleküle und polypeptide
US6211157B1 (en) 1998-05-01 2001-04-03 Sulzer Biologics, Inc. Protein mixtures to induce therapeutic angiogenesis
US6992066B2 (en) * 1998-10-16 2006-01-31 Zimmer Orthobiologics, Inc. Povidone-containing carriers for polypeptide growth factors
US7087577B2 (en) * 1998-10-16 2006-08-08 Zimmer Orthobiologies, Inc. Method of promoting natural bypass
US6727224B1 (en) 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
WO2000066620A2 (en) * 1999-04-30 2000-11-09 Curis, Inc. Morphogen-induced enhancement of fertility
JP2003505205A (ja) * 1999-07-28 2003-02-12 リジェネレーション テクノロジーズ インク． 核酸送達ビヒクルとしての軟骨マトリクス又は骨マトリクス
ATE271886T1 (de) 1999-10-15 2004-08-15 Inst Genetics Llc Hyaluronsäure enthaltende zusammensetzungen zur abgabe osteogener proteine
CN1331248A (zh) * 2000-06-30 2002-01-16 上海博德基因开发有限公司 一种新的多肽——人软骨连接蛋白10.67和编码这种多肽的多核苷酸
US6482936B1 (en) * 2001-04-17 2002-11-19 Pe Corporation (Ny) Isolated human secreted proteins, nucleic acid molecules encoding human secreted proteins, and uses thereof
WO2002099037A2 (en) * 2001-06-01 2002-12-12 Wyeth Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
US7232802B2 (en) * 2001-12-21 2007-06-19 Zimmer Orthobiologics, Inc. Compositions and methods for promoting myocardial and peripheral angiogenesis
DE602004015064D1 (de) * 2003-01-06 2008-08-28 Wyeth Corp Zusammensetzungen und verfahren zur diagnose und behandlung von kolonkrebs
US20050266409A1 (en) * 2003-02-04 2005-12-01 Wyeth Compositions and methods for diagnosing, preventing, and treating cancers
WO2005001092A2 (en) * 2003-05-20 2005-01-06 Wyeth Compositions and methods for diagnosing and treating cancers
DE602004005477T2 (de) 2003-09-12 2007-12-13 Wyeth Injizierbare feste Calciumphosphat-Stäbe zur Abgabe von osteogenen Proteinen
DE10361075A1 (de) * 2003-12-22 2005-07-28 Pac Tech - Packaging Technologies Gmbh Verfahren und Vorichtung zur Trocknung von Schaltungssubstraten
EP1571159A1 (de) * 2004-03-04 2005-09-07 Bayerische Julius-Maximilians-Universität Würzburg Mutein von Knochenmorphogenetisches Protein und seine Verwendung
WO2005116052A2 (en) * 2004-04-27 2005-12-08 Research Development Foundation ANTAGONISM OF TGF-β SUPERFAMILY RECEPTOR SIGNALING
WO2005113585A2 (en) * 2004-05-20 2005-12-01 Acceleron Pharma Inc. Modified tgf-beta superfamily polypeptides
JP2008509087A (ja) * 2004-05-27 2008-03-27 アクセルロン ファーマ インコーポレーテッド Ｔｇｆ抑制解除因子およびそれに関連する使用方法
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
US20060166251A1 (en) * 2005-01-26 2006-07-27 Archambault Joanne M Use of sFRPs as markers of BMP activity
EP1863518A2 (de) * 2005-03-30 2007-12-12 Wyeth VERFAHREN ZUR STIMULATION DES WAARWACHSTUMS MITTELS VERABREICHUNG VON BMPs
US20060247790A1 (en) * 2005-04-30 2006-11-02 Mckay William F Shaped osteochondral grafts and methods of using same
WO2007061889A2 (en) 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
US8147860B2 (en) 2005-12-06 2012-04-03 Etex Corporation Porous calcium phosphate bone material
US7659999B2 (en) * 2005-12-23 2010-02-09 Xerox Corporation UIdesign: N-up calculator user interface
EP1991282B1 (de) 2006-02-09 2013-06-19 BioMimetic Therapeutics, LLC Zusammensetzungen und verfahren zur behandlung von knochen
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
CA2656278C (en) 2006-06-30 2016-02-09 Biomimetic Therapeutics, Inc. Compositions and methods for treating rotator cuff injuries
US8524265B2 (en) 2006-08-17 2013-09-03 Warsaw Orthopedic, Inc. Medical implant sheets useful for tissue regeneration
US8106008B2 (en) 2006-11-03 2012-01-31 Biomimetic Therapeutics, Inc. Compositions and methods for arthrodetic procedures
US20080195476A1 (en) * 2007-02-09 2008-08-14 Marchese Michael A Abandonment remarketing system
ES2422259T3 (es) 2008-02-07 2013-09-10 Biomimetic Therapeutics Inc Composiciones para la osteogénesis por distracción
EP2300610A1 (de) * 2008-06-09 2011-03-30 Wyeth LLC Neue bmp-12-verwandte proteine und herstellungsverfahren dafür
KR20110067035A (ko) 2008-09-09 2011-06-20 바이오미메틱 세라퓨틱스, 인크. 건 및 인대 손상의 치료를 위한 혈소판-유래 성장 인자 조성물 및 방법
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Also Published As

Publication number Publication date
CA2265508A1 (en) 1998-03-26
JP2001500737A (ja) 2001-01-23
US5965403A (en) 1999-10-12
EP0941323A1 (de) 1999-09-15
OA10997A (en) 2003-03-04
NO991271L (no) 1999-03-16
NO991271D0 (no) 1999-03-16
FI990596A7 (fi) 1999-03-17
FI990596A0 (fi) 1999-03-17
US6331612B1 (en) 2001-12-18
WO1998012322A1 (en) 1998-03-26
US20030158379A1 (en) 2003-08-21
US6623934B2 (en) 2003-09-23
KR20000036012A (ko) 2000-06-26
CA2265508C (en) 2003-11-18

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