NO991271L - Benmorfogenetiske Protein-16-sammensetninger (BMP-16) - Google Patents
Benmorfogenetiske Protein-16-sammensetninger (BMP-16)Info
- Publication number
- NO991271L NO991271L NO991271A NO991271A NO991271L NO 991271 L NO991271 L NO 991271L NO 991271 A NO991271 A NO 991271A NO 991271 A NO991271 A NO 991271A NO 991271 L NO991271 L NO 991271L
- Authority
- NO
- Norway
- Prior art keywords
- proteins
- bmp
- compositions
- disorders
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Public Health (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fodder In General (AREA)
Abstract
Renset BMP-16 proteiner og metoder for å produsere dem er beskrevet. DNA molekyler som koder for BMP-16 proteiner er også beskrevet. Proteinene kan bli brukt i behandling av ben, brusk, andre bindevevsdefekter og forstyrrelser, inklusiv sene, ligament og meniscus, i sårheling og relatert vevsreparasjon, såvel som for behandling av forstyrrelser og defekter hos vev som inkluderer epidermisk, nerve, muskel, inklusiv hjertemuskel, og andre vev og sår, og organer slike som lever, lunge, hjerte, bukspyttkjertelen og nyrevev. Proteinene kan også være nyttige for induksjon av vekst og/eller differensiering av udifferensiert embryonale og stamceller.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/715,202 US5965403A (en) | 1996-09-18 | 1996-09-18 | Nucleic acids encoding bone morphogenic protein-16 (BMP-16) |
| PCT/US1997/011954 WO1998012322A1 (en) | 1996-09-18 | 1997-07-09 | Bone morphogenetic protein-16 (bmp-16) compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO991271L true NO991271L (no) | 1999-03-16 |
| NO991271D0 NO991271D0 (no) | 1999-03-16 |
Family
ID=24873057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO991271A NO991271D0 (no) | 1996-09-18 | 1999-03-16 | Benmorfogenetiske Protein-16-sammensetninger (BMP-16) |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US5965403A (no) |
| EP (1) | EP0941323A1 (no) |
| JP (1) | JP2001500737A (no) |
| KR (1) | KR20000036012A (no) |
| CA (1) | CA2265508C (no) |
| FI (1) | FI990596L (no) |
| NO (1) | NO991271D0 (no) |
| OA (1) | OA10997A (no) |
| WO (1) | WO1998012322A1 (no) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6150328A (en) | 1986-07-01 | 2000-11-21 | Genetics Institute, Inc. | BMP products |
| WO1993009229A1 (en) | 1991-11-04 | 1993-05-13 | Genetics Institute, Inc. | Recombinant bone morphogenetic protein heterodimers, compositions and methods of use |
| US6291206B1 (en) | 1993-09-17 | 2001-09-18 | Genetics Institute, Inc. | BMP receptor proteins |
| AU689184B2 (en) | 1993-12-07 | 1998-03-26 | Genetics Institute, Llc | BMP-12, BMP-13 and tendon-inducing compositions thereof |
| US8106001B2 (en) * | 1996-08-27 | 2012-01-31 | University Of South Florida | Diagnostic markers of human female infertility |
| US5965403A (en) * | 1996-09-18 | 1999-10-12 | Genetics Institute, Inc. | Nucleic acids encoding bone morphogenic protein-16 (BMP-16) |
| CA2279575A1 (en) * | 1997-02-06 | 1998-08-13 | Genetics Institute, Inc. | Human sdf-5 protein and compositions |
| EP1001964A4 (en) * | 1997-08-04 | 2003-04-23 | Millennium Pharm Inc | TANGO-78, TANGO-79 AND TANGO-81 NUCLEIC ACID MOLECULES |
| US6211157B1 (en) | 1998-05-01 | 2001-04-03 | Sulzer Biologics, Inc. | Protein mixtures to induce therapeutic angiogenesis |
| US6992066B2 (en) | 1998-10-16 | 2006-01-31 | Zimmer Orthobiologics, Inc. | Povidone-containing carriers for polypeptide growth factors |
| US7087577B2 (en) * | 1998-10-16 | 2006-08-08 | Zimmer Orthobiologies, Inc. | Method of promoting natural bypass |
| US6727224B1 (en) | 1999-02-01 | 2004-04-27 | Genetics Institute, Llc. | Methods and compositions for healing and repair of articular cartilage |
| AU4676600A (en) * | 1999-04-30 | 2000-11-17 | Curis, Inc. | Morphogen-induced enhancement of fertility |
| CA2379663A1 (en) * | 1999-07-28 | 2001-02-08 | Jamie M. Grooms | Cartilage or bone matrix as a nucleic acid delivery vehicle |
| DK1223990T3 (da) | 1999-10-15 | 2004-11-29 | Inst Genetics Llc | Formuleringer af hyaluronsyre til tilförsel af osteogene proteiner |
| CN1331248A (zh) * | 2000-06-30 | 2002-01-16 | 上海博德基因开发有限公司 | 一种新的多肽——人软骨连接蛋白10.67和编码这种多肽的多核苷酸 |
| US6482936B1 (en) * | 2001-04-17 | 2002-11-19 | Pe Corporation (Ny) | Isolated human secreted proteins, nucleic acid molecules encoding human secreted proteins, and uses thereof |
| US7226587B2 (en) | 2001-06-01 | 2007-06-05 | Wyeth | Compositions and methods for systemic administration of sequences encoding bone morphogenetic proteins |
| TWI267378B (en) | 2001-06-08 | 2006-12-01 | Wyeth Corp | Calcium phosphate delivery vehicles for osteoinductive proteins |
| US7232802B2 (en) * | 2001-12-21 | 2007-06-19 | Zimmer Orthobiologics, Inc. | Compositions and methods for promoting myocardial and peripheral angiogenesis |
| DE602004015064D1 (de) * | 2003-01-06 | 2008-08-28 | Wyeth Corp | Zusammensetzungen und verfahren zur diagnose und behandlung von kolonkrebs |
| WO2004070062A2 (en) * | 2003-02-04 | 2004-08-19 | Wyeth | Compositions and methods for diagnosing and treating cancers |
| US20050119210A1 (en) * | 2003-05-20 | 2005-06-02 | Xiaobing Be | Compositions and methods for diagnosing and treating cancers |
| JP5392981B2 (ja) | 2003-09-12 | 2014-01-22 | ワイス・エルエルシー | 骨形成蛋白の送達のための注入可能なリン酸カルシウム固体ロッドおよびペースト |
| DE10361075A1 (de) * | 2003-12-22 | 2005-07-28 | Pac Tech - Packaging Technologies Gmbh | Verfahren und Vorichtung zur Trocknung von Schaltungssubstraten |
| EP1571159A1 (en) * | 2004-03-04 | 2005-09-07 | Bayerische Julius-Maximilians-Universität Würzburg | Mutein of a bone morphogenetic protein and use thereof |
| EP1740609A2 (en) * | 2004-04-27 | 2007-01-10 | Research Development Foundation | Antagonism of tgf-beta superfamily receptor signaling |
| WO2005113585A2 (en) * | 2004-05-20 | 2005-12-01 | Acceleron Pharma Inc. | Modified tgf-beta superfamily polypeptides |
| AU2005250441A1 (en) * | 2004-05-27 | 2005-12-15 | Acceleron Pharma Inc. | TGF derepressors and uses related thereto |
| US7473678B2 (en) | 2004-10-14 | 2009-01-06 | Biomimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods of use thereof |
| WO2006081379A1 (en) * | 2005-01-26 | 2006-08-03 | Wyeth | Use of sfrps as markers of bmp activity |
| EP1863518A2 (en) * | 2005-03-30 | 2007-12-12 | Wyeth | Methods for stimulating hair growth by administering bmps |
| US20060247790A1 (en) * | 2005-04-30 | 2006-11-02 | Mckay William F | Shaped osteochondral grafts and methods of using same |
| KR20080084808A (ko) | 2005-11-17 | 2008-09-19 | 바이오미메틱 세라퓨틱스, 인크. | rhPDGF-BB 및 생체적합성 매트릭스를 사용하는상악안면골 보강 |
| US8147860B2 (en) | 2005-12-06 | 2012-04-03 | Etex Corporation | Porous calcium phosphate bone material |
| US7659999B2 (en) * | 2005-12-23 | 2010-02-09 | Xerox Corporation | UIdesign: N-up calculator user interface |
| ES2443581T3 (es) | 2006-02-09 | 2014-02-19 | Biomimetic Therapeutics, Llc | Composiciones y métodos para el tratamiento de hueso |
| AU2007269712B2 (en) | 2006-06-30 | 2013-02-07 | Biomimetic Therapeutics, Llc | PDGF-biomatrix compositions and methods for treating rotator cuff injuries |
| US9161967B2 (en) | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
| US8524265B2 (en) | 2006-08-17 | 2013-09-03 | Warsaw Orthopedic, Inc. | Medical implant sheets useful for tissue regeneration |
| WO2008073628A2 (en) | 2006-11-03 | 2008-06-19 | Biomimetic Therapeutics, Inc. | Compositions and methods for arthrodetic procedures |
| US20080195476A1 (en) * | 2007-02-09 | 2008-08-14 | Marchese Michael A | Abandonment remarketing system |
| AU2009212151C1 (en) | 2008-02-07 | 2015-09-17 | Stryker Corporation | Compositions and methods for distraction osteogenesis |
| US20100004175A1 (en) * | 2008-06-09 | 2010-01-07 | Tanya Shang | Novel bmp-12-related proteins and methods of their manufacture |
| BR122020000059B8 (pt) | 2008-09-09 | 2021-06-22 | Biomimetic Therapeutics Inc | composição que compreende uma matriz biocompatível e um fator de crescimento derivado de plaqueta e kit |
| US8609127B2 (en) | 2009-04-03 | 2013-12-17 | Warsaw Orthopedic, Inc. | Medical implant with bioactive material and method of making the medical implant |
| WO2010144696A1 (en) | 2009-06-11 | 2010-12-16 | Burnham Institute For Medical Research | Directed differentiation of stem cells |
| BR112012020566B1 (pt) | 2010-02-22 | 2021-09-21 | Biomimetic Therapeutics, Llc | Composição de fator de crescimento derivado de plaqueta |
| CN105198981B (zh) | 2010-08-20 | 2019-07-16 | 惠氏有限责任公司 | 经设计的成骨蛋白 |
| US9688735B2 (en) | 2010-08-20 | 2017-06-27 | Wyeth Llc | Designer osteogenic proteins |
| WO2014012101A1 (en) | 2012-07-13 | 2014-01-16 | Trustees Of Tufts College | Silk powder compaction for production of constructs with high mechanical strength and stiffness |
| EP3821880A1 (en) | 2015-10-26 | 2021-05-19 | President and Fellows of Harvard College | Oxidized polysaccharides and methods of use thereof |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5108922A (en) * | 1986-07-01 | 1992-04-28 | Genetics Institute, Inc. | DNA sequences encoding BMP-1 products |
| ZA874681B (en) * | 1986-07-01 | 1988-04-27 | Genetics Inst | Novel osteoinductive factors |
| US5187076A (en) * | 1986-07-01 | 1993-02-16 | Genetics Institute, Inc. | DNA sequences encoding BMP-6 proteins |
| US5106748A (en) * | 1986-07-01 | 1992-04-21 | Genetics Institute, Inc. | Dna sequences encoding 5 proteins |
| US5013649A (en) * | 1986-07-01 | 1991-05-07 | Genetics Institute, Inc. | DNA sequences encoding osteoinductive products |
| WO1991018098A1 (en) * | 1990-05-16 | 1991-11-28 | Genetics Institute, Inc. | Bone and cartilage inductive proteins |
| US5168050A (en) * | 1990-05-24 | 1992-12-01 | Genentech, Inc. | Mammalian expression of the bone morphogenetic protein-2b using bmp2a/bmp2b fusion |
| EP0592562B1 (en) * | 1991-06-25 | 1999-01-07 | Genetics Institute, Inc. | Bmp-9 compositions |
| DK0625989T3 (da) * | 1992-02-12 | 2000-06-26 | Bioph Biotech Entw Pharm Gmbh | DNA-sekvenser kodende for hidtil ukendte vækst-/differentieringsfaktorer |
| IL106278A0 (en) * | 1992-07-13 | 1993-11-15 | Sumitomo Metal Ind | Bone formation-inducing protein |
| EP0690871A4 (en) * | 1993-01-12 | 1999-10-20 | Univ Johns Hopkins Med | GROWTH DIFFERENTIATION FACTOR-5 |
| US5808007A (en) * | 1993-01-12 | 1998-09-15 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-3 |
| DK0690873T3 (da) * | 1993-03-19 | 2003-09-29 | Univ Johns Hopkins Med | Vækstdifferentieringsfaktor-8 |
| WO1994026892A1 (en) * | 1993-05-12 | 1994-11-24 | Genetics Institute, Inc. | Bmp-11 compositions |
| JPH09501305A (ja) * | 1993-05-12 | 1997-02-10 | ジェネティックス・インスティテュート・インコーポレイテッド | Bmp−10組成物 |
| EP0626451A3 (en) * | 1993-05-27 | 1997-11-05 | Takeda Chemical Industries, Ltd. | Heterodimers of a TGF-beta superfamily |
| AU688779B2 (en) * | 1993-07-09 | 1998-03-19 | Johns Hopkins University School Of Medicine, The | Growth differentiation factor-7 |
| WO1995001801A1 (en) * | 1993-07-09 | 1995-01-19 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-6 |
| US6204047B1 (en) * | 1993-10-08 | 2001-03-20 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-10 |
| US5439904A (en) * | 1993-12-07 | 1995-08-08 | Synphar Laboratories, Inc. | 2-spiro(2'-spirocycloalkyl)cyclopropyl cephalosporin sulfones as antiinflammatory and antigenerative agents |
| AU689184B2 (en) * | 1993-12-07 | 1998-03-26 | Genetics Institute, Llc | BMP-12, BMP-13 and tendon-inducing compositions thereof |
| EP1574577A3 (en) * | 1994-07-08 | 2006-06-14 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-11 |
| DK0770089T3 (da) * | 1994-07-13 | 2000-10-23 | Univ Johns Hopkins Med | Vækstdifferentieringsfaktor-12 |
| US5693779A (en) * | 1994-11-08 | 1997-12-02 | The United States Of America As Represented By The Department Of Health And Human Services | Production and use of anti-dorsalizing morphogenetic protein |
| US5965403A (en) * | 1996-09-18 | 1999-10-12 | Genetics Institute, Inc. | Nucleic acids encoding bone morphogenic protein-16 (BMP-16) |
-
1996
- 1996-09-18 US US08/715,202 patent/US5965403A/en not_active Expired - Fee Related
-
1997
- 1997-07-09 CA CA002265508A patent/CA2265508C/en not_active Expired - Fee Related
- 1997-07-09 EP EP97933347A patent/EP0941323A1/en not_active Ceased
- 1997-07-09 JP JP10514651A patent/JP2001500737A/ja not_active Ceased
- 1997-07-09 KR KR1019997001978A patent/KR20000036012A/ko not_active Abandoned
- 1997-07-09 FI FI990596A patent/FI990596L/fi not_active IP Right Cessation
- 1997-07-09 WO PCT/US1997/011954 patent/WO1998012322A1/en not_active Ceased
-
1999
- 1999-03-16 NO NO991271A patent/NO991271D0/no not_active Application Discontinuation
- 1999-03-18 OA OA9900059A patent/OA10997A/en unknown
- 1999-06-09 US US09/328,775 patent/US6331612B1/en not_active Expired - Fee Related
-
2001
- 2001-11-26 US US09/994,177 patent/US6623934B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001500737A (ja) | 2001-01-23 |
| KR20000036012A (ko) | 2000-06-26 |
| US20030158379A1 (en) | 2003-08-21 |
| CA2265508C (en) | 2003-11-18 |
| US6623934B2 (en) | 2003-09-23 |
| FI990596L (fi) | 1999-05-03 |
| US5965403A (en) | 1999-10-12 |
| FI990596A0 (fi) | 1999-03-17 |
| FI990596A7 (fi) | 1999-03-17 |
| WO1998012322A1 (en) | 1998-03-26 |
| US6331612B1 (en) | 2001-12-18 |
| EP0941323A1 (en) | 1999-09-15 |
| OA10997A (en) | 2003-03-04 |
| CA2265508A1 (en) | 1998-03-26 |
| NO991271D0 (no) | 1999-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |