FR06C0004I2 - Un facteur de croissance des keratinocytes (kgf) tronque a activite biologique accrue - Google Patents

Un facteur de croissance des keratinocytes (kgf) tronque a activite biologique accrue

Info

Publication number: FR06C0004I2
Authority: FR; France
Prior art keywords: kgf; growth factor; biological activity; keratinocyte growth; increased biological
Prior art date: 1993-06-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

FR06C0004C

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis Vaccines and Diagnostics Inc

Original Assignee

Novartis Vaccines and Diagnostics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-06-29

Filing date

2006-01-31

Publication date

2006-12-29

2006-01-31 Application filed by Novartis Vaccines and Diagnostics Inc filed Critical Novartis Vaccines and Diagnostics Inc

2006-03-10 Publication of FR06C0004I1 publication Critical patent/FR06C0004I1/fr

2006-12-29 Application granted granted Critical

2006-12-29 Publication of FR06C0004I2 publication Critical patent/FR06C0004I2/fr

Status Active legal-status Critical Current

Links

102000003972 Fibroblast growth factor 7 Human genes 0.000 title 2
108090000385 Fibroblast growth factor 7 Proteins 0.000 title 2
230000004071 biological effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6415—Toxins or lectins, e.g. clostridial toxins or Pseudomonas exotoxins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/642—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a cytokine, e.g. IL2, chemokine, growth factors or interferons being the inactive part of the conjugate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Toxicology (AREA)
General Chemical & Material Sciences (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Dermatology (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Immunology (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Microbiology (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Saccharide Compounds (AREA)

FR06C0004C 1993-06-29 2006-01-31 Un facteur de croissance des keratinocytes (kgf) tronque a activite biologique accrue Active FR06C0004I2 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8642793A	1993-06-29	1993-06-29
PCT/US1994/004694 WO1995001434A1 (fr)	1993-06-29	1994-04-28	Un facteur de croissance des keratinocytes (kgf) tronque a activite biologique accrue

Publications (2)

Publication Number	Publication Date
FR06C0004I1 FR06C0004I1 (fr)	2006-03-10
FR06C0004I2 true FR06C0004I2 (fr)	2006-12-29

Family

ID=22198501

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR06C0004C Active FR06C0004I2 (fr)	1993-06-29	2006-01-31	Un facteur de croissance des keratinocytes (kgf) tronque a activite biologique accrue

Country Status (25)

Country	Link
US (7)	US5677278A (fr)
EP (2)	EP1493812A3 (fr)
JP (4)	JP3570516B2 (fr)
KR (1)	KR960703433A (fr)
CN (1)	CN1129955A (fr)
AT (1)	ATE278777T1 (fr)
AU (1)	AU681405B2 (fr)
BG (1)	BG100236A (fr)
BR (1)	BR9407035A (fr)
CA (1)	CA2166278A1 (fr)
CZ (1)	CZ343795A3 (fr)
DE (2)	DE122006000005I2 (fr)
DK (1)	DK0706563T3 (fr)
ES (1)	ES2227527T3 (fr)
FI (1)	FI956203A7 (fr)
FR (1)	FR06C0004I2 (fr)
HU (1)	HUT73453A (fr)
LU (1)	LU91215I2 (fr)
NL (1)	NL300217I2 (fr)
NO (1)	NO955189D0 (fr)
NZ (1)	NZ266622A (fr)
PL (1)	PL312257A1 (fr)
PT (1)	PT706563E (fr)
SK (1)	SK153295A3 (fr)
WO (1)	WO1995001434A1 (fr)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2153816T3 (es)	1989-01-31	2001-03-16	Jeffrey S Rubin	Adn que codifica un factor de crecimiento especifico contra celulas epiteliales.
US7026291B1 (en)	1989-01-31	2006-04-11	The United States Of America As Represented By The Department Of Health And Human Services	Epithelial cell specific growth factor, keratinocyte growth factor (KGF)
US5965530A (en) *	1993-03-26	1999-10-12	Amgen Inc.	Therapeutic uses of keratinocyte growth factor
KR960703433A (ko) *	1993-06-29	1996-08-17	로버트 피. 블랙버언	증가된 생물학적 활성을 갖는 끝이 잘린 케라틴세포성장인자(kgf) (a truncated keratinocyte growth factor(kgf) having increased biological activity)
US7084119B2 (en) *	1993-06-29	2006-08-01	Chiron Corporation	Truncated keratinocyte growth factor (KGF) having increased biological activity
IL115605A (en) *	1994-10-13	2003-06-24	Amgen Inc	Method for purifying keratinocyte growth factors
US6008328A (en) *	1994-10-13	1999-12-28	Amgen Inc.	Method for purifying keratinocyte growth factors
DE69530403T2 (de) *	1994-10-13	2003-10-30	Amgen Inc., Thousand Oaks	Analogen des keratinozytenwachstumfaktors
AU745815B2 (en) *	1994-10-13	2002-04-11	Biovitrum Ab (Publ)	Analogs of keratinocyte growth factor, nucleic acids encoding such analogs, processes of making and methods of using
US6693077B1 (en)	1995-02-14	2004-02-17	Human Genome Sciences, Inc.	Keratinocyte growth factor-2
US7232667B2 (en)	1995-02-14	2007-06-19	Human Genome Sciences, Inc.	Keratinocyte growth factor-2 polynucleotides
US6077692A (en)	1995-02-14	2000-06-20	Human Genome Sciences, Inc.	Keratinocyte growth factor-2
EP1486565B1 (fr)	1995-10-11	2007-11-21	Novartis Vaccines and Diagnostics, Inc.	Combinaison de PDGF, de KGF, d'IGF et d'IGFBP pour guérir les blessures
US6692961B1 (en)	1996-10-11	2004-02-17	Invitrogen Corporation	Defined systems for epithelial cell culture and use thereof
US20030144202A1 (en) *	1996-10-15	2003-07-31	Amgen Inc.	Uses of keratinocyte growth factor-2
DK0935652T3 (da) *	1996-10-15	2004-07-26	Amgen Inc	Keratinocyt vækstfaktor-2 produkter
EP1473366A1 (fr) *	1996-10-15	2004-11-03	Amgen Inc.	Produits a base du facteur de croissance 2 des keratinocytes
US6743422B1 (en)	1996-10-15	2004-06-01	Amgen, Inc.	Keratinocyte growth factor-2 products
WO1998057976A1 (fr) *	1997-06-19	1998-12-23	Genetics Institute, Inc.	Proteines secretees et polynucleotides codant ces proteines
US20080233086A1 (en) *	1997-09-05	2008-09-25	Canbiocin Inc.	Expression Vectors for Treating Bacterial Infections
US6869927B1 (en)	1997-12-22	2005-03-22	Human Genome Sciences, Inc.	Keratinocyte growth factor-2 formulations
WO1999032135A1 (fr) *	1997-12-22	1999-07-01	Human Genome Sciences, Inc.	Formulations du facteur-2 de croissance des keratinocytes
US6599879B1 (en) *	1998-02-13	2003-07-29	Human Genome Sciences, Inc.	Therapeutic uses of keratinocyte growth factor-2
DE19934510B4 (de) *	1999-07-22	2009-04-16	Vermicon Ag	Verfahren zum Nachweis von Mikroorganismen
US6485937B1 (en)	1999-10-15	2002-11-26	The Rockefeller University	System for rapid generation of recombinant baculovirus-based expression vectors for silkworm larvae
DE10024334B4 (de) *	2000-05-17	2006-06-01	Medigene Ag	Verfahren zum Einbringen von Nukleinsäure in eine Zelle (Transfektion) mittels Calciumphosphat
AU2002236477A1 (en)	2000-11-21	2002-06-03	The Texas A & M University System	Fgf-affinity chromatography
AU2002309473A1 (en) *	2001-01-08	2002-10-08	Human Genome Sciences, Inc.	Keratinocyte growth factor-2
MXPA03007316A (es)	2001-02-19	2003-12-04	Merck Patent Gmbh	Metodo para la identificacion de epitopes de celulas t y el uso para la preparacion de moleculas con inmunogenicidad reducida.
JP2005500390A (ja)	2001-08-21	2005-01-06	カイロンコーポレイション	Ｋｇｆポリペプチド組成物
US7202066B2 (en) *	2002-01-29	2007-04-10	Carrington Laboratories, Inc.	Combination of a growth factor and a protease enzyme
GB0426394D0 (en)	2004-12-01	2005-01-05	Health Prot Agency	Fusion proteins
US8304387B2 (en) *	2004-12-15	2012-11-06	Swedish Orphan Biovitrum Ab (Publ)	Therapeutic formulations of keratinocyte growth factor
US20060183712A1 (en) *	2005-02-17	2006-08-17	The Texas A&M University System	Affinity purified heparin/heparan sulfate for controlling the biological activity of the FGF receptor
CA2630220C (fr)	2005-11-22	2020-10-13	Doris Coit	Antigenes de norovirus et de sapovirus
GB0611405D0 (en)	2006-06-09	2006-07-19	Univ Belfast	FKBP-L: A novel inhibitor of angiogenesis
US20080119433A1 (en) *	2006-07-06	2008-05-22	Aaron Thomas Tabor	Compositions and Methods for Genetic Modification of Cells Having Cosmetic Function to Enhance Cosmetic Appearance
KR101021197B1 (ko) *	2008-04-11	2011-03-11	(주)케어젠	성장인자―미미킹 펩타이드 및 그의 용도
EP2454368A4 (fr)	2009-07-17	2013-01-09	Aaron Thomas Tabor	Compositions et procédés pour la modification génétique de cellules ayant une fonction cosmétique afin d'améliorer l'aspect cosmétique
WO2015063613A2 (fr)	2013-11-01	2015-05-07	Spherium Biomed S.L.	Corps d'inclusion pour administration transdermique d'agents thérapeutiques et cosmétiques
EP4395806B1 (fr)	2021-08-30	2025-10-22	Unichem Laboratories Ltd	Compositions de protéines pour le traitement de la mucosite orale
KR102691028B1 (ko) *	2021-11-15	2024-08-05	(주)피앤피바이오팜	안정성이 증가된 인간 각질세포 성장인자1 변이체 및 이의 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2153816T3 (es)	1989-01-31	2001-03-16	Jeffrey S Rubin	Adn que codifica un factor de crecimiento especifico contra celulas epiteliales.
US5194596A (en) *	1989-07-27	1993-03-16	California Biotechnology Inc.	Production of vascular endothelial cell growth factor
US5350836A (en) *	1989-10-12	1994-09-27	Ohio University	Growth hormone antagonists
US5965530A (en)	1993-03-26	1999-10-12	Amgen Inc.	Therapeutic uses of keratinocyte growth factor
KR960703433A (ko) *	1993-06-29	1996-08-17	로버트 피. 블랙버언	증가된 생물학적 활성을 갖는 끝이 잘린 케라틴세포성장인자(kgf) (a truncated keratinocyte growth factor(kgf) having increased biological activity)
HUT78069A (hu)	1994-10-13	1999-08-30	Amgen Inc.	Keratinocita növekedési faktor analógok
DE69530403T2 (de)	1994-10-13	2003-10-30	Amgen Inc., Thousand Oaks	Analogen des keratinozytenwachstumfaktors

1994
- 1994-04-28 KR KR1019950705997A patent/KR960703433A/ko not_active Ceased
- 1994-04-28 WO PCT/US1994/004694 patent/WO1995001434A1/fr not_active Ceased
- 1994-04-28 NZ NZ266622A patent/NZ266622A/en unknown
- 1994-04-28 HU HU9503857A patent/HUT73453A/hu unknown
- 1994-04-28 EP EP04023638A patent/EP1493812A3/fr not_active Ceased
- 1994-04-28 CA CA002166278A patent/CA2166278A1/fr not_active Abandoned
- 1994-04-28 DE DE1994634053 patent/DE122006000005I2/de active Active
- 1994-04-28 CN CN94193193A patent/CN1129955A/zh active Pending
- 1994-04-28 ES ES94916597T patent/ES2227527T3/es not_active Expired - Lifetime
- 1994-04-28 DK DK94916597T patent/DK0706563T3/da active
- 1994-04-28 EP EP94916597A patent/EP0706563B1/fr not_active Expired - Lifetime
- 1994-04-28 AT AT94916597T patent/ATE278777T1/de active
- 1994-04-28 BR BR9407035A patent/BR9407035A/pt not_active Application Discontinuation
- 1994-04-28 DE DE69434053T patent/DE69434053T2/de not_active Expired - Lifetime
- 1994-04-28 CZ CZ953437A patent/CZ343795A3/cs unknown
- 1994-04-28 AU AU68208/94A patent/AU681405B2/en not_active Ceased
- 1994-04-28 PT PT94916597T patent/PT706563E/pt unknown
- 1994-04-28 PL PL94312257A patent/PL312257A1/xx unknown
- 1994-04-28 JP JP50346495A patent/JP3570516B2/ja not_active Expired - Fee Related
- 1994-04-28 SK SK1532-95A patent/SK153295A3/sk unknown
1995
- 1995-03-27 US US08/410,941 patent/US5677278A/en not_active Expired - Lifetime
- 1995-06-06 US US08/467,937 patent/US5863767A/en not_active Expired - Lifetime
- 1995-06-06 US US08/468,547 patent/US5843883A/en not_active Expired - Lifetime
- 1995-06-06 US US08/468,546 patent/US5773586A/en not_active Expired - Lifetime
- 1995-12-20 BG BG100236A patent/BG100236A/xx unknown
- 1995-12-20 NO NO955189A patent/NO955189D0/no unknown
- 1995-12-22 FI FI956203A patent/FI956203A7/fi unknown
1998
- 1998-05-08 US US09/074,950 patent/US6074848A/en not_active Expired - Lifetime
2000
- 2000-05-16 US US09/573,068 patent/US6677301B1/en not_active Expired - Fee Related
2004
- 2004-02-10 JP JP2004034289A patent/JP2004166709A/ja not_active Withdrawn
2005
- 2005-11-17 JP JP2005333438A patent/JP2006075173A/ja not_active Withdrawn
2006
- 2006-01-26 NL NL300217C patent/NL300217I2/nl unknown
- 2006-01-27 LU LU91215C patent/LU91215I2/en unknown
- 2006-01-31 FR FR06C0004C patent/FR06C0004I2/fr active Active
2007
- 2007-06-11 US US11/811,560 patent/US20090093400A1/en not_active Abandoned
2008
- 2008-11-26 JP JP2008301630A patent/JP4662569B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US6677301B1 (en)	2004-01-13
US5863767A (en)	1999-01-26
ES2227527T3 (es)	2005-04-01
JP2004166709A (ja)	2004-06-17
BR9407035A (pt)	1996-03-12
NO955189L (no)	1995-12-20
DE69434053T2 (de)	2006-02-23
DE69434053D1 (de)	2005-01-20
US5773586A (en)	1998-06-30
HUT73453A (en)	1996-08-28
DK0706563T3 (da)	2005-01-31
AU6820894A (en)	1995-01-24
JP4662569B2 (ja)	2011-03-30
HU9503857D0 (en)	1996-02-28
EP0706563B1 (fr)	2004-10-06
JPH09500267A (ja)	1997-01-14
CZ343795A3 (en)	1996-07-17
JP2006075173A (ja)	2006-03-23
ATE278777T1 (de)	2004-10-15
JP3570516B2 (ja)	2004-09-29
LU91215I2 (en)	2006-03-27
NZ266622A (en)	1997-10-24
US20090093400A1 (en)	2009-04-09
CA2166278A1 (fr)	1995-01-12
NL300217I1 (nl)	2006-04-03
EP1493812A2 (fr)	2005-01-05
PL312257A1 (en)	1996-04-01
EP0706563A1 (fr)	1996-04-17
BG100236A (en)	1996-07-31
FR06C0004I1 (fr)	2006-03-10
AU681405B2 (en)	1997-08-28
FI956203A0 (fi)	1995-12-22
FI956203A7 (fi)	1996-02-07
CN1129955A (zh)	1996-08-28
NO955189D0 (no)	1995-12-20
WO1995001434A1 (fr)	1995-01-12
US5677278A (en)	1997-10-14
KR960703433A (ko)	1996-08-17
US5843883A (en)	1998-12-01
SK153295A3 (en)	1996-11-06
DE122006000005I1 (de)	2006-08-10
PT706563E (pt)	2005-01-31
EP1493812A3 (fr)	2006-02-08
NL300217I2 (nl)	2006-05-01
DE122006000005I2 (de)	2006-11-23
US6074848A (en)	2000-06-13
JP2009062396A (ja)	2009-03-26

Publication	Publication Date	Title
FR06C0004I2 (fr)	2006-12-29	Un facteur de croissance des keratinocytes (kgf) tronque a activite biologique accrue
EP0717633A4 (fr)	1998-05-20	Facteur 7 de differenciation de la croissance
DE69117052D1 (de)	1996-03-21	Automatischer biologischer reaktor
DK39692D0 (da)	1992-03-25	Biologisk materiale
DE69631593D1 (de)	2004-03-25	Herzklappenhalter für eine herzklappenprothese
HU9302666D0 (en)	1994-01-28	Biological insecticide
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