FR12C0064I2 - Compositions pharmaceutiques injectables d'un derive d'anthracenedione avec action anti-tumorale - Google Patents

Compositions pharmaceutiques injectables d'un derive d'anthracenedione avec action anti-tumorale

Info

Publication number: FR12C0064I2
Authority: FR; France
Prior art keywords: pharmaceutical compositions; injectable pharmaceutical; antitumor action; anthracenedione derivative; anthracenedione
Prior art date: 2002-05-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

FR12C0064C

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Cell Therapeutics Europe SRL

Original Assignee

Cell Therapeutics Europe SRL

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-05-16

Filing date

2012-10-25

Publication date

2013-08-16

2012-10-25 Application filed by Cell Therapeutics Europe SRL filed Critical Cell Therapeutics Europe SRL

2012-12-14 Publication of FR12C0064I1 publication Critical patent/FR12C0064I1/fr

2013-08-16 Application granted granted Critical

2013-08-16 Publication of FR12C0064I2 publication Critical patent/FR12C0064I2/fr

Status Active legal-status Critical Current

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
RGHILYZRVFRRNK-UHFFFAOYSA-N anthracene-1,2-dione Chemical class C1=CC=C2C=C(C(C(=O)C=C3)=O)C3=CC2=C1 RGHILYZRVFRRNK-UHFFFAOYSA-N 0.000 title 1
230000000259 anti-tumor effect Effects 0.000 title 1
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
SVAGFBGXEWPNJC-SPIKMXEPSA-N 6,9-bis(2-aminoethylamino)benzo[g]isoquinoline-5,10-dione;(z)-but-2-enedioic acid Chemical compound OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.O=C1C2=CN=CC=C2C(=O)C2=C1C(NCCN)=CC=C2NCCN SVAGFBGXEWPNJC-SPIKMXEPSA-N 0.000 abstract 1
229920002307 Dextran Polymers 0.000 abstract 1
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
239000008101 lactose Substances 0.000 abstract 1
239000000843 powder Substances 0.000 abstract 1
239000011780 sodium chloride Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Inorganic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biochemistry (AREA)
Oil, Petroleum & Natural Gas (AREA)
Molecular Biology (AREA)
Dermatology (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

FR12C0064C 2002-05-16 2012-10-25 Compositions pharmaceutiques injectables d'un derive d'anthracenedione avec action anti-tumorale Active FR12C0064I2 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT2002MI001040A ITMI20021040A1 (it)	2002-05-16	2002-05-16	Composizioni farmaceutiche iniettabili di un derivato antracenedionico ad attivita' antitumorale
PCT/EP2003/004871 WO2003097101A1 (fr)	2002-05-16	2003-05-09	Compositions pharmaceutiques injectables d'un derive d'anthracenedione avec action anti-tumorale

Publications (2)

Publication Number	Publication Date
FR12C0064I1 FR12C0064I1 (fr)	2012-12-14
FR12C0064I2 true FR12C0064I2 (fr)	2013-08-16

Family

ID=11449903

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR12C0064C Active FR12C0064I2 (fr)	2002-05-16	2012-10-25	Compositions pharmaceutiques injectables d'un derive d'anthracenedione avec action anti-tumorale

Country Status (12)

Country	Link
US (3)	US20060199831A1 (fr)
EP (1)	EP1503797B1 (fr)
JP (1)	JP4624780B2 (fr)
AT (1)	ATE381944T1 (fr)
AU (1)	AU2003240613A1 (fr)
CA (1)	CA2486001C (fr)
DE (1)	DE60318310T2 (fr)
ES (1)	ES2298521T3 (fr)
FR (1)	FR12C0064I2 (fr)
IT (1)	ITMI20021040A1 (fr)
MX (1)	MXPA04011348A (fr)
WO (1)	WO2003097101A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2106788A1 (fr) *	2008-04-04	2009-10-07	Ipsen Pharma	Formulations liquides et lyophilisées
CN105769776B (zh) *	2016-03-26	2018-05-11	青岛市肿瘤医院	一种治疗非霍奇金淋巴瘤的冻干组合物及其制备方法
CN105769757B (zh) *	2016-03-26	2018-05-25	青岛市肿瘤医院	一种治疗非霍奇金淋巴瘤的注射液及其制备方法
CN105997896B (zh) *	2016-05-28	2019-07-05	长沙秋点兵信息科技有限公司	治疗非霍奇金淋巴瘤的注射用冻干粉及其制备方法
CN106176630B (zh) *	2016-08-03	2019-01-04	湖北丽益医药科技有限公司	一种注射用马来酸匹杉琼无菌粉末的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3590124A (en) *	1967-06-27	1971-06-29	Us Navy	Blood transfusion fluids having reduced turbulent friction properties
JP2690009B2 (ja) *	1986-07-10	1997-12-10	エーザイ株式会社	セフアロスポリン注射剤
IE920754A1 (en)	1991-03-08	1992-09-09	Univ Vermont	6,9 BIS(SUBSTITUTED-AMINO) BENZO[g]-ISOQUINOLINE-5,10-DIONES
JP3501471B2 (ja) *	1992-06-15	2004-03-02	旭化成ファーマ株式会社	カルシトニン類の安定化組成物および安定化法
JPH08126685A (ja) *	1994-01-26	1996-05-21	Shionogi & Co Ltd	デキストラン類の凍結乾燥方法
US5587382A (en) *	1994-03-28	1996-12-24	Boehringer Mannheim Italia, Spa	6,9-bis[(2-aminoethyl) amino]benzo [g]isoquinoline-5,10- dione dimaleate; an aza-anthracenedione with reduced cardiotoxicity
JP2001522833A (ja) *	1997-11-10	2001-11-20	ジー・ディー・サール・アンド・カンパニー	多剤耐性を治療するためのアルキル化イミノ糖類の使用
GB9808922D0 (en) *	1998-04-24	1998-06-24	Cantab Pharmaceuticals Res Ltd	Virus preparations
TWI233805B (en) *	1999-07-01	2005-06-11	Fujisawa Pharmaceutical Co	Stabilized pharmaceutical composition in lyophilized form as antifungal agent
IT1315253B1 (it) *	1999-10-22	2003-02-03	Novuspharma Spa	Preparazione liposomiale di 6,9-bis-(2-amminoetil)ammino\|benzog\|isochinolin-5,10-dione dimaleato

2002
- 2002-05-16 IT IT2002MI001040A patent/ITMI20021040A1/it unknown
2003
- 2003-05-09 AU AU2003240613A patent/AU2003240613A1/en not_active Abandoned
- 2003-05-09 CA CA2486001A patent/CA2486001C/fr not_active Expired - Lifetime
- 2003-05-09 ES ES03729997T patent/ES2298521T3/es not_active Expired - Lifetime
- 2003-05-09 AT AT03729997T patent/ATE381944T1/de not_active IP Right Cessation
- 2003-05-09 WO PCT/EP2003/004871 patent/WO2003097101A1/fr not_active Ceased
- 2003-05-09 US US10/514,301 patent/US20060199831A1/en not_active Abandoned
- 2003-05-09 JP JP2004505097A patent/JP4624780B2/ja not_active Expired - Lifetime
- 2003-05-09 DE DE60318310T patent/DE60318310T2/de not_active Expired - Lifetime
- 2003-05-09 EP EP03729997A patent/EP1503797B1/fr not_active Expired - Lifetime
- 2003-05-09 MX MXPA04011348A patent/MXPA04011348A/es active IP Right Grant
2010
- 2010-12-10 US US12/964,861 patent/US9211262B2/en not_active Expired - Lifetime
2012
- 2012-10-25 FR FR12C0064C patent/FR12C0064I2/fr active Active
2015
- 2015-11-10 US US14/937,689 patent/US20160256557A1/en not_active Abandoned

Also Published As

Publication number	Publication date
ES2298521T3 (es)	2008-05-16
US20160256557A1 (en)	2016-09-08
JP2005530792A (ja)	2005-10-13
JP4624780B2 (ja)	2011-02-02
CA2486001C (fr)	2010-04-13
EP1503797B1 (fr)	2007-12-26
US9211262B2 (en)	2015-12-15
ITMI20021040A1 (it)	2003-11-17
WO2003097101A1 (fr)	2003-11-27
CA2486001A1 (fr)	2003-11-27
DE60318310T2 (de)	2008-12-11
US20060199831A1 (en)	2006-09-07
AU2003240613A1 (en)	2003-12-02
EP1503797A1 (fr)	2005-02-09
FR12C0064I1 (fr)	2012-12-14
ITMI20021040A0 (it)	2002-05-16
MXPA04011348A (es)	2005-08-15
ATE381944T1 (de)	2008-01-15
DE60318310D1 (de)	2008-02-07
US20110144147A1 (en)	2011-06-16

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NO20061840L (no)	2006-06-26	Legemiddelbelegg som tilveiebringer hoy legemiddeltilsetning og fremgangsmater for a tilveiebringe samme
WO2007008752A3 (fr)	2007-04-26	Compositions pharmaceutiques a liberation prolongee pour medicaments tres solubles dans l'eau
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MY129356A (en)	2007-03-30	Electrospun pharmaceutical compositions
PT1416935E (pt)	2008-06-18	Derivados de 4-amino-6-fenil-pirrolo[2,3-d]pirimidina
IL153297A0 (en)	2003-07-06	Compounds and compositions for delivering active agents
MXPA01008611A (es)	2003-06-24	Compuestos y composiciones para suministrar agentes activos.
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FR12C0064I1 (fr)	2012-12-14
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