FR1456789A - Procédé pour éliminer sélectivement des groupes de protection lors de la synthèse de peptides - Google Patents

Procédé pour éliminer sélectivement des groupes de protection lors de la synthèse de peptides

Info

Publication number
FR1456789A
FR1456789A FR30587A FR30587A FR1456789A FR 1456789 A FR1456789 A FR 1456789A FR 30587 A FR30587 A FR 30587A FR 30587 A FR30587 A FR 30587A FR 1456789 A FR1456789 A FR 1456789A
Authority
FR
France
Prior art keywords
protective groups
peptide synthesis
selectively removing
groups during
during peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR30587A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
BASF Schweiz AG
Original Assignee
Ciba Geigy AG
Ciba AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1180364A external-priority patent/CH451960A/de
Application filed by Ciba Geigy AG, Ciba AG filed Critical Ciba Geigy AG
Priority to FR30587A priority Critical patent/FR1456789A/fr
Application granted granted Critical
Publication of FR1456789A publication Critical patent/FR1456789A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C07K1/122—Hydrolysis with acids different from HF
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • C07K5/06052—Val-amino acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
FR30587A 1964-09-10 1965-09-07 Procédé pour éliminer sélectivement des groupes de protection lors de la synthèse de peptides Expired FR1456789A (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR30587A FR1456789A (fr) 1964-09-10 1965-09-07 Procédé pour éliminer sélectivement des groupes de protection lors de la synthèse de peptides

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH1180364A CH451960A (de) 1964-09-10 1964-09-10 Verfahren zur selektiven Abspaltung von Sulfenyl-Schutzgruppen aus N-Sulfenyl-Aminosäurederivaten
CH106765 1965-01-26
CH1110865 1965-08-06
FR30587A FR1456789A (fr) 1964-09-10 1965-09-07 Procédé pour éliminer sélectivement des groupes de protection lors de la synthèse de peptides

Publications (1)

Publication Number Publication Date
FR1456789A true FR1456789A (fr) 1966-07-08

Family

ID=27428077

Family Applications (1)

Application Number Title Priority Date Filing Date
FR30587A Expired FR1456789A (fr) 1964-09-10 1965-09-07 Procédé pour éliminer sélectivement des groupes de protection lors de la synthèse de peptides

Country Status (1)

Country Link
FR (1) FR1456789A (fr)

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