FR1614M - Nouveau dérivé d'imidazoline et ses sels d'addition acides. - Google Patents

Nouveau dérivé d'imidazoline et ses sels d'addition acides.

Info

Publication number
FR1614M
FR1614M FR879728A FR879728A FR1614M FR 1614 M FR1614 M FR 1614M FR 879728 A FR879728 A FR 879728A FR 879728 A FR879728 A FR 879728A FR 1614 M FR1614 M FR 1614M
Authority
FR
France
Prior art keywords
imidazoline
acid addition
addition salts
new derivative
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR879728A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck KGaA
Original Assignee
E Merck AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E Merck AG filed Critical E Merck AG
Application granted granted Critical
Publication of FR1614M publication Critical patent/FR1614M/fr
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR879728A 1960-11-23 1961-11-22 Nouveau dérivé d'imidazoline et ses sels d'addition acides. Active FR1614M (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEM47194A DE1121054B (de) 1960-11-23 1960-11-23 Verfahren zur Herstellung eines neuen Imidazolinderivates und dessen Saeureadditionssalzen

Publications (1)

Publication Number Publication Date
FR1614M true FR1614M (fr) 1962-12-17

Family

ID=7305839

Family Applications (1)

Application Number Title Priority Date Filing Date
FR879728A Active FR1614M (fr) 1960-11-23 1961-11-22 Nouveau dérivé d'imidazoline et ses sels d'addition acides.

Country Status (6)

Country Link
US (2) US3161653A (fr)
CH (1) CH446353A (fr)
DE (1) DE1121054B (fr)
FR (1) FR1614M (fr)
GB (1) GB951989A (fr)
SE (1) SE305877B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1595234A1 (de) * 1965-04-27 1970-03-05 Roehm & Haas Gmbh Verfahren zur Herstellung oligomerer bzw. polymerer Amine
US3438995A (en) * 1968-01-08 1969-04-15 Melville Sahyun Diazaheterocyclic substituted benz-oxaheterocyclic compounds
GB1333471A (en) * 1971-01-27 1973-10-10 Labaz Imidazoline derivatives and process for preparing the same
US4978332A (en) * 1987-09-28 1990-12-18 Matrix Pharmaceutical, Inc. Treatments employing vasoconstrictive substances in combination with cytotoxic agents for introduction into cellular lesion areas
WO1996032130A1 (fr) * 1995-04-10 1996-10-17 Baxter International Inc. Utilisation d'hemoglobine reticulee dans le traitement des hemorragies sous-arachnoidiennes
AU2201699A (en) * 1997-12-19 1999-07-12 Eli Lilly And Company Hypoglycemic imidazoline compounds
JP2009524617A (ja) * 2006-01-27 2009-07-02 エフ．ホフマン−ラ ロシュ アーゲー 置換２−イミダゾール又はイミダゾリン誘導体の使用
AU2007312390B2 (en) * 2006-10-19 2013-03-28 F. Hoffmann-La Roche Ag Aminomethyl-4-imidazoles
DE602007005671D1 (de) * 2006-10-19 2010-05-12 Hoffmann La Roche Aminomethyl-2-imidazole mit affinität zu mit dem trace-amin assoziierten rezeptoren
AU2007316257A1 (en) * 2006-11-02 2008-05-08 F. Hoffmann-La Roche Ag Substituted 2-imidazoles as modulators of the trace amine associated receptors
WO2008058867A2 (fr) * 2006-11-16 2008-05-22 F. Hoffmann-La Roche Ag 4-imidazoles substitués
KR101189348B1 (ko) * 2006-12-13 2012-10-09 에프. 호프만-라 로슈 아게 미량 아민 결합 수용체(ｔａａｒ)에 대한 리간드로서의 신규한 2-이미다졸
US20080146523A1 (en) * 2006-12-18 2008-06-19 Guido Galley Imidazole derivatives
ES2510546T3 (es) 2007-02-02 2014-10-21 F. Hoffmann-La Roche Ag Nuevas 2-aminooxazolinas como ligandos TAAR1 para trastornos del SNC
MX2009008465A (es) * 2007-02-15 2009-08-20 Hoffmann La Roche Nuevas 2-aminooxazolinas como ligandos de taar1.
CN101687812A (zh) 2007-07-02 2010-03-31 弗·哈夫曼-拉罗切有限公司 对痕量胺相关受体(taar)具有良好亲和性的2-咪唑啉化合物
KR101150628B1 (ko) * 2007-07-03 2012-05-31 에프. 호프만-라 로슈 아게 4-이미다졸린 및 항우울제로서 이의 용도
CN101765587A (zh) * 2007-07-27 2010-06-30 弗·哈夫曼-拉罗切有限公司 作为taar配体的2-氮杂环丁烷甲胺类和2-吡咯烷甲胺类
AU2008281877A1 (en) * 2007-08-02 2009-02-05 F. Hoffmann-La Roche Ag The use of benzamide derivatives for the treatment of CNS disorders
KR101167773B1 (ko) * 2007-08-03 2012-07-24 에프. 호프만-라 로슈 아게 Ｔａａｒ１ 리간드로서의 피리딘카복스아마이드 및 벤즈아마이드 유도체
US8242153B2 (en) * 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
AU2009273324A1 (en) * 2008-07-24 2010-01-28 F. Hoffmann-La Roche Ag 4,5-dihydro-oxazol-2-yl derivatives
US20100311798A1 (en) * 2009-06-05 2010-12-09 Decoret Guillaume 2-aminooxazolines as taar1 ligands
US8354441B2 (en) * 2009-11-11 2013-01-15 Hoffmann-La Roche Inc. Oxazoline derivatives
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
MY195528A (en) 2016-03-17 2023-01-30 Hoffmann La Roche 5-Ethyl-4-Methyl-Pyrazole-3-Carboxamide Derivative Having Activity as Agonist of Taar

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2965648A (en) * 1960-12-20 Certain i-alkenyl benzimidazoles
DE1049387B (de) * 1959-01-29 Ciba Aktiengesellschaft, Basel (Schweiz) Verfahren zur Herstellung eines neuen Imidazolins
US2441867A (en) * 1943-11-19 1948-05-18 Recip Ab Methods of producing 2-(alpha-naphthylmethyl)-imidazoline
US2457047A (en) * 1946-02-13 1948-12-21 Monsanto Chemicals 2-(2'-thenyl)-4, 5-dihydroimidazoles and process for making the same
US2780577A (en) * 1951-05-26 1957-02-05 Burroughs Wellcome Co Inhibiting polymethylene diquaternary curariform activity by alpha-stilbazoline derivatives
US2744909A (en) * 1955-06-27 1956-05-08 Bristol Lab Inc 2-(ortho-phenylbenzyl) imidazoline and acid addition salts
US3024248A (en) * 1956-09-18 1962-03-06 Ciba Pharm Prod Inc Organic sulfur compounds and method for producing same
US2955073A (en) * 1958-06-02 1960-10-04 Burroughs Wellcome Co Method of treating febrile convulsions
NL242891A (fr) * 1958-09-02
US3010972A (en) * 1960-03-18 1961-11-28 Smith Kline French Lab Condensed cyclopropyl amine derivatives
US3042674A (en) * 1960-07-12 1962-07-03 Sahyun Xanthene and thiaxanthene cyclic amidines

Also Published As

Publication number Publication date
GB951989A (en) 1964-03-11
US3161653A (en) 1964-12-15
SE305877B (fr) 1968-11-11
CH446353A (de) 1967-11-15
DE1121054B (de) 1962-01-04
US3238101A (en) 1966-03-01

Similar Documents

Publication Publication Date Title
FR1313754A (fr) Production d'oxazolidines et tétrahydrooxazines substituées
BE598944A (fr) Sels ammoniques organiques de l'acide vinylsulfonique
FR1177733A (fr) Dérviés d'acides amidophosphoriques
BE618672A (fr) Esters basiques d'acides l-benzoxa-cycloalkanecarboxyliques
FR1845M (fr) Nouvelles dihydrodibenzoxazépines et leurs sels d'addition d'acides.
FR1560M (fr) Nouveau nonadécapeptide de la formule l-séryl-l-tyrosyl-l-séryl-méthionyl-l-glutaminyl-l-histidyl-l-phénylalanyl-l-arginyl-l-tryptophyl-glycyl-l-lysyl-l-prolyl-l-valyl-glycyl-l-lysyl-l-lysyl-l-arginyl-l-arginyl-l-proline et ses dérivés et sels utilisables en thérapeutique.
BE580680A (fr) Ester d'acides O,O,-dialcoyl-thiolphosphoriques et O,O-dialcoyl-dithiophosphoriques et de N-alcoyl-lactames et -thiolactames.
FR1282518A (fr) Dérivés nu-acylés d'acides (3.5-diamino-2. 4. 6-tri-iodo-benzoyl)-aminés
BE597859R (fr) Alcoyl-pénicillines alpha-substituées et leurs sels
FR1281M (fr) Nouveau médicament constitué par l'acide α(3-acétylamino-2,4,6-tri-iodo-phénoxy)-caproique, ou ses sels.
FR1848M (fr) Dérivés des dihydrodibenzothiazocines et leurs sels d'addition d'acide.
FR2710M (fr) Nouveau dérivé de la guanidine et ses sels d'addition avec les acides.
FR1033M (fr) Nouvelle pénicilline et ses sels non toxiques.
FR1561M (fr) Nouveau nonadécapeptide de la formule l-séryl-l-tyrosyl-l-séryl-l-méthionyl-l-glutamyl-l-histidyl-l-phénylalanyl-l-arginyl-l-tryptophyl-glycyl-l-lysyl-l-prolyl-l-valyl-glycyl-l-lysyl-l-lysyl-l-arginyl-l-arginyl-l-proline et sels utilisables en thérapeutique.
FR329M (fr) Nouveau dérivé d'acide hydroxamique utilisable en thérapeutique.
FR1337759A (fr) Sels d'ammonium monoquaternaires
FR2051M (fr) Nouveau tétracosapeptide de la formule l - séryl - l -tyrosyl - l - séryl - l - méthionyl - l - glutamyl - l - histidyl - l - phénylalanyl - l - arginyl - l - tryptophyl - glycyl - l - lysyl - l - prolyl - l - valyl - glycyl - l - lysyl - l - lysyl - l - arginyl - l - arginyl - l - prolyl - l - valyl - l - lysyl - l - valyl - l - tyrosyl - l - proline et ses sels utilisables en thérapeutique.
FR1267M (fr) Sels de sodium et de potassium d'esters sulfuriques de dextrane.
BE606257A (fr) alpha-Enolacylates d'acides beta-acyl-gamma-phényl-alpha-tétroniques
FR1323577A (fr) Préparation de sels d'acides hydroxy-alcane-sulfoniques et des sultones correspondantes
FR1273571A (fr) Acides inhibés et non corrosifs
FR1308M (fr) Nouvelles amides d'acides organiques.
FR2119M (fr) La 1'allyl-4-phényl-4-carbopropoxypipéridine, et ses sels d'addition d'acides.
BE605038A (fr) Solutions aqueuses d'hydroxocobalamine
FI35485A (fi) Menetelmä penisilliinin ja sen myrkyttömien suolojen valmistamiseksi