FR2012022A1 - Benzodiazepine compounds psychosedatives, antidepressives - Google Patents
Benzodiazepine compounds psychosedatives, antidepressivesInfo
- Publication number
- FR2012022A1 FR2012022A1 FR6918042A FR6918042A FR2012022A1 FR 2012022 A1 FR2012022 A1 FR 2012022A1 FR 6918042 A FR6918042 A FR 6918042A FR 6918042 A FR6918042 A FR 6918042A FR 2012022 A1 FR2012022 A1 FR 2012022A1
- Authority
- FR
- France
- Prior art keywords
- lower alkyl
- carbamoyl
- amino
- alkyl
- substd
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000001430 anti-depressive effect Effects 0.000 title abstract 2
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 8
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- 239000000543 intermediate Substances 0.000 abstract 2
- -1 trifluoremethyl Chemical group 0.000 abstract 2
- XAKBSHICSHRJCL-UHFFFAOYSA-N [CH2]C(=O)C1=CC=CC=C1 Chemical group [CH2]C(=O)C1=CC=CC=C1 XAKBSHICSHRJCL-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229940049706 benzodiazepine Drugs 0.000 abstract 1
- 150000001557 benzodiazepines Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4572268 | 1968-07-01 | ||
| JP6270068 | 1968-08-31 | ||
| JP6269968 | 1968-08-31 | ||
| JP7601268 | 1968-10-18 | ||
| JP43076013A JPS4830076B1 (fr) | 1968-10-18 | 1968-10-18 | |
| JP7749868 | 1968-10-24 | ||
| JP7749968 | 1968-10-24 | ||
| JP7876868 | 1968-10-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2012022A1 true FR2012022A1 (en) | 1970-03-13 |
| FR2012022B1 FR2012022B1 (fr) | 1973-07-13 |
Family
ID=27572335
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR6918042A Granted FR2012022A1 (en) | 1968-07-01 | 1969-06-02 | Benzodiazepine compounds psychosedatives, antidepressives |
Country Status (3)
| Country | Link |
|---|---|
| BG (2) | BG19177A3 (fr) |
| FR (1) | FR2012022A1 (fr) |
| OA (1) | OA04237A (fr) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0000299A1 (fr) * | 1977-06-16 | 1979-01-10 | Pierre Fabre S.A. | Nouveaux dérivés de benzoyl-2-chloro-4-glycinanilides substitués, leur procédé de préparation et leur application en tant que médicaments. |
| EP0022017A1 (fr) * | 1979-06-25 | 1981-01-07 | Pierre Fabre S.A. | Nouveaux dérivés de benzoyl-2 nitro-4 anilides, leur préparation et leur application en tant que médicaments |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE706803A (fr) * | 1966-11-23 | 1968-05-21 |
-
1968
- 1968-12-29 BG BG011347A patent/BG19177A3/xx unknown
- 1968-12-29 BG BG012138A patent/BG17604A3/xx unknown
-
1969
- 1969-02-13 OA OA53508A patent/OA04237A/fr unknown
- 1969-06-02 FR FR6918042A patent/FR2012022A1/fr active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE706803A (fr) * | 1966-11-23 | 1968-05-21 |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0000299A1 (fr) * | 1977-06-16 | 1979-01-10 | Pierre Fabre S.A. | Nouveaux dérivés de benzoyl-2-chloro-4-glycinanilides substitués, leur procédé de préparation et leur application en tant que médicaments. |
| EP0022017A1 (fr) * | 1979-06-25 | 1981-01-07 | Pierre Fabre S.A. | Nouveaux dérivés de benzoyl-2 nitro-4 anilides, leur préparation et leur application en tant que médicaments |
| FR2459793A1 (fr) * | 1979-06-25 | 1981-01-16 | Fabre Sa Pierre | Nouveaux derives de benzoyl-2 nitro-4 anilides, leur preparation et leur application en tant que medicaments |
Also Published As
| Publication number | Publication date |
|---|---|
| OA04237A (fr) | 1979-12-31 |
| BG19177A3 (bg) | 1975-04-30 |
| BG17604A3 (bg) | 1973-11-10 |
| FR2012022B1 (fr) | 1973-07-13 |
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