FR2014831A1 - Quinuclidinyl and quinuclidinylalkyl ethers with cholino - lytic, antihistaminic and neurosedative activity - Google Patents
Quinuclidinyl and quinuclidinylalkyl ethers with cholino - lytic, antihistaminic and neurosedative activityInfo
- Publication number
- FR2014831A1 FR2014831A1 FR6924509A FR6924509A FR2014831A1 FR 2014831 A1 FR2014831 A1 FR 2014831A1 FR 6924509 A FR6924509 A FR 6924509A FR 6924509 A FR6924509 A FR 6924509A FR 2014831 A1 FR2014831 A1 FR 2014831A1
- Authority
- FR
- France
- Prior art keywords
- quinuclidinylalkyl
- neurosedative
- antihistaminic
- quinuclidinyl
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 230000001387 anti-histamine Effects 0.000 title abstract 2
- 239000000739 antihistaminic agent Substances 0.000 title abstract 2
- 230000003153 cholinolytic effect Effects 0.000 title abstract 2
- 230000003010 neurosedative effect Effects 0.000 title abstract 2
- 125000004621 quinuclidinyl group Chemical group N12C(CC(CC1)CC2)* 0.000 title abstract 2
- 150000002170 ethers Chemical class 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- IVLICPVPXWEGCA-UHFFFAOYSA-N 3-quinuclidinol Chemical compound C1C[C@@H]2C(O)C[N@]1CC2 IVLICPVPXWEGCA-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 150000003242 quaternary ammonium salts Chemical class 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229940100198 alkylating agent Drugs 0.000 abstract 1
- 239000002168 alkylating agent Substances 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 125000000664 diazo group Chemical group [N-]=[N+]=[*] 0.000 abstract 1
- 125000005059 halophenyl group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- SBYHFKPVCBCYGV-UHFFFAOYSA-N quinuclidine Chemical group C1CC2CCN1CC2 SBYHFKPVCBCYGV-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3684368 | 1968-08-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2014831A1 true FR2014831A1 (en) | 1970-04-24 |
Family
ID=10391632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR6924509A Withdrawn FR2014831A1 (en) | 1968-08-01 | 1969-07-18 | Quinuclidinyl and quinuclidinylalkyl ethers with cholino - lytic, antihistaminic and neurosedative activity |
Country Status (3)
| Country | Link |
|---|---|
| AT (2) | AT291273B (fr) |
| DE (1) | DE1938546A1 (fr) |
| FR (1) | FR2014831A1 (fr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8528633D0 (en) * | 1985-11-21 | 1985-12-24 | Beecham Group Plc | Compounds |
| EP0322182A3 (fr) * | 1987-12-22 | 1992-01-02 | Beecham Group Plc | Composés azabicycliques, procédé pour leur préparation et compositions pharmaceutiques les contenant |
| DE3839385A1 (de) * | 1988-11-22 | 1990-05-23 | Boehringer Ingelheim Kg | Neue quinuclidine, ihre herstellung als arzneimittel und verfahren zu ihrer herstellung |
| YU84791A (sh) * | 1990-05-19 | 1994-06-10 | Boehringer Ingelheim Kg. | Biciklicni 1-aza-cikloalkalni |
| FR2862647B1 (fr) | 2003-11-25 | 2008-07-04 | Aventis Pharma Sa | Derives de pyrazolyle, procede de preparation et intermediaires de ce procede a titre de medicaments et de compositions pharmaceutiques les renfermant |
| DK1790643T3 (da) | 2004-09-15 | 2010-08-16 | Shuqiang Zhao | Quinuclidinforbindelser med kvaternær ammoniumgruppe, fremgangsmåde til fremstilling heraf og anvendelse som blokeringsmidler for acetylcholin |
-
1969
- 1969-07-18 FR FR6924509A patent/FR2014831A1/fr not_active Withdrawn
- 1969-07-29 DE DE19691938546 patent/DE1938546A1/de active Pending
- 1969-07-31 AT AT738869A patent/AT291273B/de not_active IP Right Cessation
- 1969-07-31 AT AT614670A patent/AT298502B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE1938546A1 (de) | 1970-03-26 |
| AT298502B (de) | 1972-05-10 |
| AT291273B (de) | 1971-07-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |