FR2020209A1 - Antibiotic acylxymethyl 7-(alpha-amino-alpha-phenyl- - acetamido)-3-methyl-delta-3-cephem-4-carboxylates - Google Patents
Antibiotic acylxymethyl 7-(alpha-amino-alpha-phenyl- - acetamido)-3-methyl-delta-3-cephem-4-carboxylatesInfo
- Publication number
- FR2020209A1 FR2020209A1 FR6934152A FR6934152A FR2020209A1 FR 2020209 A1 FR2020209 A1 FR 2020209A1 FR 6934152 A FR6934152 A FR 6934152A FR 6934152 A FR6934152 A FR 6934152A FR 2020209 A1 FR2020209 A1 FR 2020209A1
- Authority
- FR
- France
- Prior art keywords
- alpha
- amino
- right arrow
- convert
- acylxymethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000003377 acid catalyst Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000005278 alkyl sulfonyloxy group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000005279 aryl sulfonyloxy group Chemical group 0.000 abstract 1
- 125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- KHIWWQKSHDUIBK-UHFFFAOYSA-N periodic acid Chemical compound OI(=O)(=O)=O KHIWWQKSHDUIBK-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4792868 | 1968-10-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2020209A1 true FR2020209A1 (en) | 1970-07-10 |
Family
ID=10446763
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR6934152A Withdrawn FR2020209A1 (en) | 1968-10-09 | 1969-10-07 | Antibiotic acylxymethyl 7-(alpha-amino-alpha-phenyl- - acetamido)-3-methyl-delta-3-cephem-4-carboxylates |
Country Status (3)
| Country | Link |
|---|---|
| CH (1) | CH525241A (fr) |
| DE (1) | DE1951012A1 (fr) |
| FR (1) | FR2020209A1 (fr) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2216288A1 (en) * | 1973-02-07 | 1974-08-30 | Politechnika Gdanska | Cephalosporin acetoxymethyl esters - useful as antibacterials and cephalosporin inters |
| FR2459244A1 (fr) * | 1979-06-14 | 1981-01-09 | Ausonia Farma Srl | Procede de preparation du chlorhydrate de 7-(a-amino-a-phenylacetamido)-3-methyl-d3-cephem-4-carboxylate de pivaloyloxymethyle |
| FR2478103A1 (fr) * | 1980-03-14 | 1981-09-18 | Dobfar Spa | Esters de cephapirine, leurs sels et leurs procedes de fabrication |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1364672A (en) * | 1971-06-09 | 1974-08-29 | Beecham Group Ltd | Penicillins |
| GB1406113A (en) * | 1972-10-05 | 1975-09-17 | Leo Pharm Prod Ltd | Process for the preparation of cephalosporin estets |
| DK0504107T3 (da) * | 1991-03-11 | 1995-02-13 | Schweizerhall Saeurefab | Fremgangsmåde til fremstilling af chlorerede carboxylsyreestere |
| ATE115538T1 (de) * | 1991-03-11 | 1994-12-15 | Schweizerhall Saeurefab | Verfahren zur herstellung von halogenierten carbonsäureestern. |
-
1969
- 1969-10-07 FR FR6934152A patent/FR2020209A1/fr not_active Withdrawn
- 1969-10-09 CH CH1519369A patent/CH525241A/de not_active IP Right Cessation
- 1969-10-09 DE DE19691951012 patent/DE1951012A1/de active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2216288A1 (en) * | 1973-02-07 | 1974-08-30 | Politechnika Gdanska | Cephalosporin acetoxymethyl esters - useful as antibacterials and cephalosporin inters |
| FR2459244A1 (fr) * | 1979-06-14 | 1981-01-09 | Ausonia Farma Srl | Procede de preparation du chlorhydrate de 7-(a-amino-a-phenylacetamido)-3-methyl-d3-cephem-4-carboxylate de pivaloyloxymethyle |
| FR2478103A1 (fr) * | 1980-03-14 | 1981-09-18 | Dobfar Spa | Esters de cephapirine, leurs sels et leurs procedes de fabrication |
Also Published As
| Publication number | Publication date |
|---|---|
| CH525241A (de) | 1972-07-15 |
| DE1951012A1 (de) | 1970-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |