FR2076787A5 - Lyophilisation stabiliser - for viruses contg potassium phosphate lactose and albumin - Google Patents
Lyophilisation stabiliser - for viruses contg potassium phosphate lactose and albuminInfo
- Publication number
- FR2076787A5 FR2076787A5 FR7002975A FR7002975A FR2076787A5 FR 2076787 A5 FR2076787 A5 FR 2076787A5 FR 7002975 A FR7002975 A FR 7002975A FR 7002975 A FR7002975 A FR 7002975A FR 2076787 A5 FR2076787 A5 FR 2076787A5
- Authority
- FR
- France
- Prior art keywords
- viruses
- albumin
- contg
- potassium phosphate
- lyophilisation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000004108 freeze drying Methods 0.000 title abstract 3
- 102000009027 Albumins Human genes 0.000 title abstract 2
- 108010088751 Albumins Proteins 0.000 title abstract 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 title abstract 2
- 241000700605 Viruses Species 0.000 title abstract 2
- 239000008101 lactose Substances 0.000 title abstract 2
- 239000003381 stabilizer Substances 0.000 title abstract 2
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 title 2
- 229910000160 potassium phosphate Inorganic materials 0.000 title 1
- 235000011009 potassium phosphates Nutrition 0.000 title 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- -1 potassium cations Chemical class 0.000 abstract 1
- 201000005404 rubella Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55583—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/36011—Togaviridae
- C12N2770/36211—Rubivirus, e.g. rubella virus
- C12N2770/36251—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7002975A FR2076787A5 (en) | 1970-01-28 | 1970-01-28 | Lyophilisation stabiliser - for viruses contg potassium phosphate lactose and albumin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7002975A FR2076787A5 (en) | 1970-01-28 | 1970-01-28 | Lyophilisation stabiliser - for viruses contg potassium phosphate lactose and albumin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2076787A5 true FR2076787A5 (en) | 1971-10-15 |
Family
ID=9049721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7002975A Expired FR2076787A5 (en) | 1970-01-28 | 1970-01-28 | Lyophilisation stabiliser - for viruses contg potassium phosphate lactose and albumin |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2076787A5 (fr) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4337242A (en) * | 1980-02-05 | 1982-06-29 | Merck & Co., Inc. | Vaccine stabilizer containing L-glutamic acid and L-arginine |
| US4338335A (en) * | 1980-02-05 | 1982-07-06 | Merck & Co., Inc. | Vaccine stabilizer containing L-glutamic acid and L-arginine |
| FR2505657A1 (fr) * | 1981-05-13 | 1982-11-19 | Pasteur Institut | Perfectionnements apportes aux agents de stabilisation de virus vivants pour la preparation de vaccins, et vaccins stabilises contenant lesdits agents de stabilisation |
| FR2532548A1 (fr) * | 1982-09-03 | 1984-03-09 | Pasteur Institut | Nouveau procede de production de vaccins presentant un titre eleve de virus et vaccins tres purifies, a titre eleve de virus, ainsi obtenus |
| EP0028563B1 (fr) * | 1979-10-29 | 1984-04-04 | Merck & Co. Inc. | Stabilisant pour vaccins liquides et vaccin liquide contenant ledit stabilisant |
| US4555401A (en) * | 1980-07-03 | 1985-11-26 | The Green Cross Corporation | Live mumps vaccine and method of stabilizing the same |
| WO1995010601A1 (fr) * | 1993-10-12 | 1995-04-20 | Chiron Viagene, Inc. | Procedes de conservation de virus de recombinaison |
| WO2001005941A3 (fr) * | 1999-07-16 | 2001-07-19 | Health Lab Service Board | Conservation de micro-organismes, de cellules et de tissus |
| EP0872249A4 (fr) * | 1995-03-17 | 2001-10-24 | Hisamitsu Pharmaceutical Co | Preparation de transfert genique |
| RU2686108C2 (ru) * | 2012-10-02 | 2019-04-24 | Трансген Са | Вирусосодержащий препарат и его применение |
Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL124941C (fr) * | ||||
| NL296078A (fr) * | ||||
| US2912361A (en) * | 1956-11-28 | 1959-11-10 | Sterling Drug Inc | Canine distemper vaccine and its preparation |
| US3014843A (en) * | 1955-02-07 | 1961-12-26 | Armour & Co | Method of producing non-virulent strains of attenuated and stabilized hog cholera virus |
| FR1299503A (fr) * | 1960-01-18 | 1962-07-27 | Anchor Serum Company | Procédé d'atténuation de virus de la rhinotrachéite infectieuse des bovins |
| GB1000907A (en) * | 1961-11-08 | 1965-08-11 | Dow Chemical Co | Attenuated live measles virus vaccine and method of production |
| DE1209245B (de) * | 1961-11-08 | 1966-01-20 | Dow Chemical Co | Verfahren zur Herstellung von Masernimpfstoffen |
| GB1049386A (en) * | 1962-08-16 | 1966-11-23 | Parke Davis & Co | Improvements in or relating to stabilized virus antigens |
| BE685270A (fr) * | 1965-08-13 | 1967-02-09 | ||
| BE700795A (fr) * | 1965-07-29 | 1968-01-02 | ||
| BE701496A (fr) * | 1967-05-22 | 1968-01-18 | ||
| US3366543A (en) * | 1964-08-17 | 1968-01-30 | American Home Prod | Process of attenuating infectious bovine rhinotracheitis viruses |
| BE720444A (fr) * | 1967-09-05 | 1969-03-05 | ||
| GB1152626A (en) * | 1967-07-07 | 1969-05-21 | Merck & Co Inc | Rubella Vaccine |
-
1970
- 1970-01-28 FR FR7002975A patent/FR2076787A5/fr not_active Expired
Patent Citations (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL296078A (fr) * | ||||
| NL124941C (fr) * | ||||
| US3014843A (en) * | 1955-02-07 | 1961-12-26 | Armour & Co | Method of producing non-virulent strains of attenuated and stabilized hog cholera virus |
| US2912361A (en) * | 1956-11-28 | 1959-11-10 | Sterling Drug Inc | Canine distemper vaccine and its preparation |
| FR1299503A (fr) * | 1960-01-18 | 1962-07-27 | Anchor Serum Company | Procédé d'atténuation de virus de la rhinotrachéite infectieuse des bovins |
| GB1000907A (en) * | 1961-11-08 | 1965-08-11 | Dow Chemical Co | Attenuated live measles virus vaccine and method of production |
| DE1209245B (de) * | 1961-11-08 | 1966-01-20 | Dow Chemical Co | Verfahren zur Herstellung von Masernimpfstoffen |
| GB1049386A (en) * | 1962-08-16 | 1966-11-23 | Parke Davis & Co | Improvements in or relating to stabilized virus antigens |
| US3366543A (en) * | 1964-08-17 | 1968-01-30 | American Home Prod | Process of attenuating infectious bovine rhinotracheitis viruses |
| BE700795A (fr) * | 1965-07-29 | 1968-01-02 | ||
| BE685270A (fr) * | 1965-08-13 | 1967-02-09 | ||
| BE701496A (fr) * | 1967-05-22 | 1968-01-18 | ||
| GB1152645A (en) * | 1967-05-22 | 1969-05-21 | Merck & Co Inc | Rubella Vaccine |
| FR1583642A (fr) * | 1967-05-22 | 1969-11-21 | ||
| GB1152626A (en) * | 1967-07-07 | 1969-05-21 | Merck & Co Inc | Rubella Vaccine |
| BE720444A (fr) * | 1967-09-05 | 1969-03-05 | ||
| NL6812467A (fr) * | 1967-09-05 | 1969-03-07 |
Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0028563B1 (fr) * | 1979-10-29 | 1984-04-04 | Merck & Co. Inc. | Stabilisant pour vaccins liquides et vaccin liquide contenant ledit stabilisant |
| US4338335A (en) * | 1980-02-05 | 1982-07-06 | Merck & Co., Inc. | Vaccine stabilizer containing L-glutamic acid and L-arginine |
| US4337242A (en) * | 1980-02-05 | 1982-06-29 | Merck & Co., Inc. | Vaccine stabilizer containing L-glutamic acid and L-arginine |
| US4555401A (en) * | 1980-07-03 | 1985-11-26 | The Green Cross Corporation | Live mumps vaccine and method of stabilizing the same |
| US4500512A (en) * | 1981-05-13 | 1985-02-19 | Institut Pasteur | Stabilizing agents for live viruses for preparing vaccines, and stabilized vaccines containing said stabilizing agents |
| EP0065905A1 (fr) * | 1981-05-13 | 1982-12-01 | Institut Pasteur | Perfectionnements apportés aux agents de stabilisation de virus vivants pour la préparation de vaccins, et vaccins stabilisés contenant lesdits agents de stabilisation |
| FR2505657A1 (fr) * | 1981-05-13 | 1982-11-19 | Pasteur Institut | Perfectionnements apportes aux agents de stabilisation de virus vivants pour la preparation de vaccins, et vaccins stabilises contenant lesdits agents de stabilisation |
| FR2532548A1 (fr) * | 1982-09-03 | 1984-03-09 | Pasteur Institut | Nouveau procede de production de vaccins presentant un titre eleve de virus et vaccins tres purifies, a titre eleve de virus, ainsi obtenus |
| WO1995010601A1 (fr) * | 1993-10-12 | 1995-04-20 | Chiron Viagene, Inc. | Procedes de conservation de virus de recombinaison |
| US5792643A (en) * | 1993-10-12 | 1998-08-11 | Herrmann; Steven M. | Methods for preserving recombinant retroviruses |
| EP0872249A4 (fr) * | 1995-03-17 | 2001-10-24 | Hisamitsu Pharmaceutical Co | Preparation de transfert genique |
| WO2001005941A3 (fr) * | 1999-07-16 | 2001-07-19 | Health Lab Service Board | Conservation de micro-organismes, de cellules et de tissus |
| RU2686108C2 (ru) * | 2012-10-02 | 2019-04-24 | Трансген Са | Вирусосодержащий препарат и его применение |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |