FR2112084A1 - Cyclic (iso)adenosine-3' 5'-monophosphoric - acid derivs - Google Patents
Cyclic (iso)adenosine-3' 5'-monophosphoric - acid derivsInfo
- Publication number
- FR2112084A1 FR2112084A1 FR7035682A FR7035682A FR2112084A1 FR 2112084 A1 FR2112084 A1 FR 2112084A1 FR 7035682 A FR7035682 A FR 7035682A FR 7035682 A FR7035682 A FR 7035682A FR 2112084 A1 FR2112084 A1 FR 2112084A1
- Authority
- FR
- France
- Prior art keywords
- cpds
- prepd
- iso
- monophosphoric
- cyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 125000004122 cyclic group Chemical group 0.000 title abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- 239000000055 Corticotropin-Releasing Hormone Substances 0.000 abstract 1
- QOSSAOTZNIDXMA-UHFFFAOYSA-N Dicylcohexylcarbodiimide Chemical compound C1CCCCC1N=C=NC1CCCCC1 QOSSAOTZNIDXMA-UHFFFAOYSA-N 0.000 abstract 1
- 206010062767 Hypophysitis Diseases 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 229910019213 POCl3 Inorganic materials 0.000 abstract 1
- AUYYCJSJGJYCDS-LBPRGKRZSA-N Thyrolar Chemical class IC1=CC(C[C@H](N)C(O)=O)=CC(I)=C1OC1=CC=C(O)C(I)=C1 AUYYCJSJGJYCDS-LBPRGKRZSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000031709 bromination Effects 0.000 abstract 1
- 238000005893 bromination reaction Methods 0.000 abstract 1
- 125000004063 butyryl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003246 corticosteroid Substances 0.000 abstract 1
- IDLFZVILOHSSID-OVLDLUHVSA-N corticotropin Chemical compound C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)NC(=O)[C@@H](N)CO)C1=CC=C(O)C=C1 IDLFZVILOHSSID-OVLDLUHVSA-N 0.000 abstract 1
- 229960000258 corticotropin Drugs 0.000 abstract 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 230000000865 phosphorylative effect Effects 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 239000005495 thyroid hormone Substances 0.000 abstract 1
- 229940036555 thyroid hormone Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7035682A FR2112084A1 (en) | 1970-10-02 | 1970-10-02 | Cyclic (iso)adenosine-3' 5'-monophosphoric - acid derivs |
| GB1336443D GB1336443A (en) | 1969-10-10 | 1970-10-07 | Preparation of ,3,5-nucleotides |
| GB1340270A GB1336444A (en) | 1969-10-10 | 1970-10-07 | Adenosine-5,-monophosphoric acids |
| GB1336442D GB1336442A (en) | 1969-10-10 | 1970-10-07 | Preparation of adenosine-3,5-monophosphoric acid derivatives |
| GB4773170A GB1336441A (en) | 1969-10-10 | 1970-10-07 | Derivatives of cyclo adenosine-3,5-phosphoric acid and their preparation |
| DE19702065809 DE2065809A1 (de) | 1969-10-10 | 1970-10-09 | In 8-stellung substituierte adenosin-5'-monophosphorsaeuren |
| DE19702049638 DE2049638A1 (de) | 1969-10-10 | 1970-10-09 | Isomere Nukleosiddenvate und Ver fahren zu ihrer Herstellung |
| CA095,217A CA979890A (en) | 1969-10-10 | 1970-10-09 | Derives d'acide adenosine -3',5'-phosphorique cyclique et leur preparation |
| CH1596771A CH535791A (fr) | 1969-10-10 | 1970-10-09 | Procédé de préparation de nouveaux dérivés d'acide adénosine-3',5'-phosphorique cyclique et leur utilisation |
| SE7013709A SE400296B (sv) | 1969-10-10 | 1970-10-09 | Forfarande for framstellning av derivat av cyklisk adenosin-3',5'-monofosforsyra |
| CH1500570A CH531009A (fr) | 1969-10-10 | 1970-10-09 | Procédé de préparation de nouveaux dérivés d'acide adénosine-3',5'-phosphorique cyclique et leur utilisation |
| JP45089620A JPS5022559B1 (fr) | 1969-10-10 | 1970-10-12 | |
| US00080223A US3856776A (en) | 1969-10-10 | 1970-10-12 | Derivatives of cyclo adenosine-3 -,5 -phosphoric acid and their preparation |
| SE7314163A SE412240B (sv) | 1969-10-10 | 1973-10-18 | Forfarande for framstellning av cykliska adenosinfosforsyraderivat |
| CA194,485A CA980343A (en) | 1969-10-10 | 1974-03-08 | Adenosine-5'-monophosphoric acids |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7035682A FR2112084A1 (en) | 1970-10-02 | 1970-10-02 | Cyclic (iso)adenosine-3' 5'-monophosphoric - acid derivs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2112084A1 true FR2112084A1 (en) | 1972-06-16 |
| FR2112084B1 FR2112084B1 (fr) | 1973-06-08 |
Family
ID=9062195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7035682A Granted FR2112084A1 (en) | 1969-10-10 | 1970-10-02 | Cyclic (iso)adenosine-3' 5'-monophosphoric - acid derivs |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2112084A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54103891A (en) * | 1978-01-28 | 1979-08-15 | Kikkoman Corp | Novel 2-fluoro-adenosine-3',5'-cyclic phosphoric acid and its preparation |
-
1970
- 1970-10-02 FR FR7035682A patent/FR2112084A1/fr active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54103891A (en) * | 1978-01-28 | 1979-08-15 | Kikkoman Corp | Novel 2-fluoro-adenosine-3',5'-cyclic phosphoric acid and its preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2112084B1 (fr) | 1973-06-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |