FR2296405A1 - Nouveaux derives de l'acide phenyl-acetique, leur preparation et les medicaments qui les renferment - Google Patents

Nouveaux derives de l'acide phenyl-acetique, leur preparation et les medicaments qui les renferment

Info

Publication number
FR2296405A1
FR2296405A1 FR7443223A FR7443223A FR2296405A1 FR 2296405 A1 FR2296405 A1 FR 2296405A1 FR 7443223 A FR7443223 A FR 7443223A FR 7443223 A FR7443223 A FR 7443223A FR 2296405 A1 FR2296405 A1 FR 2296405A1
Authority
FR
France
Prior art keywords
hypolipaemic
phenylacetic acid
alkylhalo
halophenyl
saponifying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7443223A
Other languages
English (en)
Other versions
FR2296405B1 (fr
Inventor
Henry Najer
Don Pierre Rene Luc Giudicelli
Philippe Michel Jacque Manoury
Jean-Marie Louis Eugene Roger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR7443223A priority Critical patent/FR2296405A1/fr
Priority to DE19752557517 priority patent/DE2557517C3/de
Priority to IL48707A priority patent/IL48707A0/xx
Priority to NL7514970A priority patent/NL7514970A/xx
Priority to ES443912A priority patent/ES443912A1/es
Priority to SE7514687A priority patent/SE7514687L/sv
Priority to FI753670A priority patent/FI753670A7/fi
Priority to ZA00758007A priority patent/ZA758007B/xx
Priority to LU74115A priority patent/LU74115A1/xx
Priority to BE163164A priority patent/BE837138A/fr
Priority to GR49689A priority patent/GR57855B/el
Priority to DK591975A priority patent/DK591975A/da
Priority to NO754406A priority patent/NO754406L/no
Priority to US05/645,351 priority patent/US4067996A/en
Priority to AU87945/75A priority patent/AU8794575A/en
Priority to JP51001075A priority patent/JPS51125245A/ja
Publication of FR2296405A1 publication Critical patent/FR2296405A1/fr
Application granted granted Critical
Publication of FR2296405B1 publication Critical patent/FR2296405B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D317/34—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/045—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis by substitution of a group bound to the ring by nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR7443223A 1974-12-30 1974-12-30 Nouveaux derives de l'acide phenyl-acetique, leur preparation et les medicaments qui les renferment Granted FR2296405A1 (fr)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FR7443223A FR2296405A1 (fr) 1974-12-30 1974-12-30 Nouveaux derives de l'acide phenyl-acetique, leur preparation et les medicaments qui les renferment
DE19752557517 DE2557517C3 (de) 1974-12-30 1975-12-19 Phenylessigsäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
IL48707A IL48707A0 (en) 1974-12-30 1975-12-22 Novel phenylacetic acid derivatives,their preparation and pharmaceutical compositions containing them
NL7514970A NL7514970A (nl) 1974-12-30 1975-12-23 Werkwijze voor het bereiden van een geneesmid- del, zo gevormd geneesmiddel en werkwijze voor het bereiden van daartoe geschikte actieve componenten.
ES443912A ES443912A1 (es) 1974-12-30 1975-12-27 Procedimiento para preparar derivados del acido fenil-aceti-co.
BE163164A BE837138A (fr) 1974-12-30 1975-12-29 Derives de l'acide phenylacetique
ZA00758007A ZA758007B (en) 1974-12-30 1975-12-29 Phenylacetic acid derivatives
LU74115A LU74115A1 (fr) 1974-12-30 1975-12-29
SE7514687A SE7514687L (sv) 1974-12-30 1975-12-29 Fenylettiksyraderivat
GR49689A GR57855B (en) 1974-12-30 1975-12-29 Procede de preparation de derives de l'acide phenylacetique
DK591975A DK591975A (da) 1974-12-30 1975-12-29 Fremgangsmade til fremstilling af phenyleddikesyrederivater
NO754406A NO754406L (fr) 1974-12-30 1975-12-29
FI753670A FI753670A7 (fr) 1974-12-30 1975-12-29
AU87945/75A AU8794575A (en) 1974-12-30 1975-12-30 Phenylacetic acid derivatives
US05/645,351 US4067996A (en) 1974-12-30 1975-12-30 Phenylacetic acid derivatives
JP51001075A JPS51125245A (en) 1974-12-30 1976-01-05 Phenyl acetic acid derivatives and hyperlipidemia treating agent containing same as effective component

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7443223A FR2296405A1 (fr) 1974-12-30 1974-12-30 Nouveaux derives de l'acide phenyl-acetique, leur preparation et les medicaments qui les renferment

Publications (2)

Publication Number Publication Date
FR2296405A1 true FR2296405A1 (fr) 1976-07-30
FR2296405B1 FR2296405B1 (fr) 1978-07-21

Family

ID=9146738

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7443223A Granted FR2296405A1 (fr) 1974-12-30 1974-12-30 Nouveaux derives de l'acide phenyl-acetique, leur preparation et les medicaments qui les renferment

Country Status (3)

Country Link
BE (1) BE837138A (fr)
FR (1) FR2296405A1 (fr)
ZA (1) ZA758007B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2424247A2 (fr) * 1978-04-27 1979-11-23 Science Union & Cie Nouveaux derives d'acides arylalcanoiques a action hypolipemiante et leurs procedes d'obtention

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2424247A2 (fr) * 1978-04-27 1979-11-23 Science Union & Cie Nouveaux derives d'acides arylalcanoiques a action hypolipemiante et leurs procedes d'obtention

Also Published As

Publication number Publication date
FR2296405B1 (fr) 1978-07-21
BE837138A (fr) 1976-06-29
ZA758007B (en) 1976-12-29

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