FR2378094A2 - Nouveaux reactifs biologiques constitues par des supports solides sur lesquels sont couples des composes organiques comportant un residu glucidique - Google Patents
Nouveaux reactifs biologiques constitues par des supports solides sur lesquels sont couples des composes organiques comportant un residu glucidiqueInfo
- Publication number
- FR2378094A2 FR2378094A2 FR7701889A FR7701889A FR2378094A2 FR 2378094 A2 FR2378094 A2 FR 2378094A2 FR 7701889 A FR7701889 A FR 7701889A FR 7701889 A FR7701889 A FR 7701889A FR 2378094 A2 FR2378094 A2 FR 2378094A2
- Authority
- FR
- France
- Prior art keywords
- opt
- antibody
- diagnosis
- support
- insoluble support
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 3
- 238000003745 diagnosis Methods 0.000 title abstract 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 4
- 235000001014 amino acid Nutrition 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 229920001817 Agar Polymers 0.000 abstract 1
- 102000008946 Fibrinogen Human genes 0.000 abstract 1
- 108010049003 Fibrinogen Proteins 0.000 abstract 1
- 201000005505 Measles Diseases 0.000 abstract 1
- 229920005654 Sephadex Polymers 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 150000004982 aromatic amines Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000011805 ball Substances 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- -1 diacid Chemical class 0.000 abstract 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229940012952 fibrinogen Drugs 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 108010074605 gamma-Globulins Proteins 0.000 abstract 1
- 239000011521 glass Substances 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 206010022000 influenza Diseases 0.000 abstract 1
- 239000004816 latex Substances 0.000 abstract 1
- 229920000126 latex Polymers 0.000 abstract 1
- 239000011806 microball Substances 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 229920000768 polyamine Polymers 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 201000005404 rubella Diseases 0.000 abstract 1
- 230000035945 sensitivity Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Réactifs biologiques. Ces réactifs sont obtenus par couplage d'anticorps spécifiques à l'égard d'antigènes correspondant à des états pathologiques donnés, lesquels anticorps appartiennent au groupe des glycoprotéines, sur un support insoluble porteur de chaînes latérales obtenues par fixation, par liaisons de covalence, de composés comportant un groupement -NH2 réactif, éventuellement eux-mêmes couplés avec un composé azoté comportant éventuellement en outre un groupement -SH. Application de ces réactifs au diagnostic de diverses maladies ou d'états pathologiques particuliers.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7701889A FR2378094A2 (fr) | 1977-01-24 | 1977-01-24 | Nouveaux reactifs biologiques constitues par des supports solides sur lesquels sont couples des composes organiques comportant un residu glucidique |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7701889A FR2378094A2 (fr) | 1977-01-24 | 1977-01-24 | Nouveaux reactifs biologiques constitues par des supports solides sur lesquels sont couples des composes organiques comportant un residu glucidique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2378094A2 true FR2378094A2 (fr) | 1978-08-18 |
| FR2378094B2 FR2378094B2 (fr) | 1980-06-20 |
Family
ID=9185823
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7701889A Granted FR2378094A2 (fr) | 1977-01-24 | 1977-01-24 | Nouveaux reactifs biologiques constitues par des supports solides sur lesquels sont couples des composes organiques comportant un residu glucidique |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2378094A2 (fr) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1987003206A1 (fr) * | 1985-11-25 | 1987-06-04 | Quash Gerard A | Glycoproteines virales modifiees, utilisations diagnostiques et therapeutiques |
| US4965069A (en) * | 1985-11-25 | 1990-10-23 | Quash Gerard A | Oxidized viruses or viral antigens and utilization for diagnostic prophylactic and/or therapeutic applications |
| EP1762250A1 (fr) * | 2005-09-12 | 2007-03-14 | Fresenius Kabi Deutschland GmbH | Conjugués d' amidon hydroxyalkyle et une substance active obtenue par ligation chimique via thiazolidine |
| US7538092B2 (en) | 2002-10-08 | 2009-05-26 | Fresenius Kabi Deutschland Gmbh | Pharmaceutically active oligosaccharide conjugates |
| US7541328B2 (en) | 2002-03-06 | 2009-06-02 | Fresenius Kabi Deutschland Gmbh | Coupling proteins to a modified polysaccharide |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2450877A1 (fr) | 1979-03-06 | 1980-10-03 | Inst Nat Sante Rech Med | Nouveaux tests par agglutination pour la detection des virus de la grippe, et reactifs pour la realisation de ces tests |
| DE10112825A1 (de) | 2001-03-16 | 2002-10-02 | Fresenius Kabi De Gmbh | HESylierung von Wirkstoffen in wässriger Lösung |
| DE10209822A1 (de) | 2002-03-06 | 2003-09-25 | Biotechnologie Ges Mittelhesse | Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid |
| BR0314227A (pt) | 2002-09-11 | 2005-10-25 | Fresenius Kabi De Gmbh | Derivados de amido de hidroxialquila |
| WO2005014655A2 (fr) | 2003-08-08 | 2005-02-17 | Fresenius Kabi Deutschland Gmbh | Conjugues d'amidon d'hydroxyalkyle et de proteine |
| JP5191729B2 (ja) | 2004-03-11 | 2013-05-08 | フレゼニウス・カビ・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 還元的アミノ化によって製造される、ヒドロキシアルキルデンプンとタンパク質とのコンジュゲート |
-
1977
- 1977-01-24 FR FR7701889A patent/FR2378094A2/fr active Granted
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1987003206A1 (fr) * | 1985-11-25 | 1987-06-04 | Quash Gerard A | Glycoproteines virales modifiees, utilisations diagnostiques et therapeutiques |
| US4965069A (en) * | 1985-11-25 | 1990-10-23 | Quash Gerard A | Oxidized viruses or viral antigens and utilization for diagnostic prophylactic and/or therapeutic applications |
| US7541328B2 (en) | 2002-03-06 | 2009-06-02 | Fresenius Kabi Deutschland Gmbh | Coupling proteins to a modified polysaccharide |
| US7538092B2 (en) | 2002-10-08 | 2009-05-26 | Fresenius Kabi Deutschland Gmbh | Pharmaceutically active oligosaccharide conjugates |
| EP1762250A1 (fr) * | 2005-09-12 | 2007-03-14 | Fresenius Kabi Deutschland GmbH | Conjugués d' amidon hydroxyalkyle et une substance active obtenue par ligation chimique via thiazolidine |
| WO2007031266A3 (fr) * | 2005-09-12 | 2007-09-20 | Fresenius Kabi De Gmbh | Conjugues d'amidon hydroxyalkyle et d'une substance active, prepares par ligature chimique par l'intermediaire de la thiazolidine |
| JP2009507973A (ja) * | 2005-09-12 | 2009-02-26 | フレゼニウス・カビ・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | チアゾリジンを介する化学結合により製造したヒドロキシアルキルデンプンと活性物質のコンジュゲート |
| EA013910B1 (ru) * | 2005-09-12 | 2010-08-30 | Фрезениус Каби Дойчланд Гмбх | Конъюгаты гидроксиалкилкрахмала и действующего вещества, полученные химическим лигированием через тиазолидин |
| AU2006291527B2 (en) * | 2005-09-12 | 2012-03-22 | Fresenius Kabi Deutschland Gmbh | Conjugates of hydroxyalkyl starch and an active substance, prepared by chemical ligation via thiazolidine |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2378094B2 (fr) | 1980-06-20 |
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