BG96346A - Специфични свързващи вещества - Google Patents

Специфични свързващи вещества

Info

Publication number
BG96346A
BG96346A BG096346A BG9634692A BG96346A BG 96346 A BG96346 A BG 96346A BG 096346 A BG096346 A BG 096346A BG 9634692 A BG9634692 A BG 9634692A BG 96346 A BG96346 A BG 96346A
Authority
BG
Bulgaria
Prior art keywords
specific binding
binding substances
plar
reshaped
human antibody
Prior art date
Application number
BG096346A
Other languages
English (en)
Other versions
BG60687B1 (bg
Inventor
Martine Verhoeyen
Original Assignee
Unilever N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898926045A external-priority patent/GB8926045D0/en
Priority claimed from GB909019552A external-priority patent/GB9019552D0/en
Application filed by Unilever N.V. filed Critical Unilever N.V.
Publication of BG96346A publication Critical patent/BG96346A/bg
Publication of BG60687B1 publication Critical patent/BG60687B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Dental Preparations (AREA)
  • Paper (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Fireproofing Substances (AREA)

Abstract

Изобретението се отнася до преоформено човешко антитяло или негов фрагмент със специфичност за човешка плацентарна алкална фосфатаза (рlар), получено чрез пренасяне на определящи комплементарността зони (сdr) от миша анти-рlар хибридомна клетъчна линия н17е2 в човешка антитяло вариабилна структура. Преоформената молекула може да бъде използвана при третирането или диагностицирането на рака. 29 претенции, 13 фигури
BG96346A 1989-11-17 1992-05-15 Специфични свързващи вещества BG60687B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898926045A GB8926045D0 (en) 1989-11-17 1989-11-17 Specific binding agents
GB909019552A GB9019552D0 (en) 1990-09-07 1990-09-07 Specific binding agents
PCT/GB1990/001755 WO1991007500A1 (en) 1989-11-17 1990-11-14 Specific binding agents

Publications (2)

Publication Number Publication Date
BG96346A true BG96346A (bg) 1993-12-24
BG60687B1 BG60687B1 (bg) 1995-12-29

Family

ID=26296218

Family Applications (1)

Application Number Title Priority Date Filing Date
BG96346A BG60687B1 (bg) 1989-11-17 1992-05-15 Специфични свързващи вещества

Country Status (16)

Country Link
EP (1) EP0429242B1 (bg)
JP (1) JPH05501357A (bg)
KR (2) KR970007782B1 (bg)
AT (1) ATE123815T1 (bg)
AU (1) AU652923B2 (bg)
BG (1) BG60687B1 (bg)
CA (1) CA2066670A1 (bg)
DE (1) DE69020112T2 (bg)
DK (1) DK0429242T3 (bg)
ES (1) ES2075169T3 (bg)
FI (1) FI922220L (bg)
GR (1) GR3017407T3 (bg)
HU (1) HUT64600A (bg)
NO (2) NO303066B1 (bg)
RO (1) RO110262B1 (bg)
WO (1) WO1991007500A1 (bg)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9019553D0 (en) * 1990-09-07 1990-10-24 Unilever Plc Specific binding agents
WO1994004679A1 (en) * 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
US6800738B1 (en) 1991-06-14 2004-10-05 Genentech, Inc. Method for making humanized antibodies
EP0590058B1 (en) 1991-06-14 2003-11-26 Genentech, Inc. HUMANIZED Heregulin ANTIBODy
GB0510790D0 (en) 2005-05-26 2005-06-29 Syngenta Crop Protection Ag Anti-CD16 binding molecules
JP5297742B2 (ja) * 2008-09-26 2013-09-25 株式会社青木科学研究所 金型用粉体含有油性潤滑剤、これを用いた静電塗布方法、及び静電塗布装置
EP3383920B1 (en) * 2015-11-30 2024-01-10 The Regents of the University of California Tumor-specific payload delivery and immune activation using a human antibody targeting a highly specific tumor cell surface antigen
EP3806894A4 (en) 2018-06-12 2022-06-08 Promab Biotechnologies, Inc. PLAP-CAR EFFECTOR CELLS
US20240101677A1 (en) 2021-01-27 2024-03-28 Innovent Biologics (Suzhou) Co., Ltd. Single-domain antibody against cd16a and use thereof
MX2024003887A (es) 2021-10-14 2024-07-09 Arsenal Biosciences Inc Células inmunitarias que tienen arnch coespresados y sistemas de compuerta lógica.
CN114014933B (zh) * 2021-11-17 2023-05-02 福州迈新生物技术开发有限公司 抗plap蛋白单克隆抗体、细胞系及其制备方法和应用
EP4766737A1 (en) * 2023-08-25 2026-07-01 Axcynsis Therapeutics Pte. Ltd. Anti-PALP/PALPL2 antibodies, antibody-drug combinations and their uses

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607679D0 (en) * 1986-03-27 1986-04-30 Winter G P Recombinant dna product

Also Published As

Publication number Publication date
DE69020112T2 (de) 1995-11-02
AU652923B2 (en) 1994-09-15
NO921941L (no) 1992-05-15
RO110262B1 (ro) 1995-11-30
EP0429242A3 (en) 1991-06-05
DE69020112D1 (de) 1995-07-20
ATE123815T1 (de) 1995-06-15
AU6736990A (en) 1991-06-13
KR920703837A (ko) 1992-12-18
EP0429242A2 (en) 1991-05-29
EP0429242B1 (en) 1995-06-14
JPH05501357A (ja) 1993-03-18
KR970007783B1 (ko) 1997-05-16
FI922220A0 (fi) 1992-05-15
WO1991007500A1 (en) 1991-05-30
FI922220A7 (fi) 1992-05-15
KR970007782B1 (ko) 1997-05-16
NO921941D0 (no) 1992-05-15
GR3017407T3 (en) 1995-12-31
NO980656L (no) 1992-05-15
HUT64600A (en) 1994-01-28
ES2075169T3 (es) 1995-10-01
FI922220L (fi) 1992-05-15
HU9201619D0 (en) 1992-08-28
NO980656D0 (no) 1998-02-16
BG60687B1 (bg) 1995-12-29
NO303066B1 (no) 1998-05-25
DK0429242T3 (da) 1995-10-16
CA2066670A1 (en) 1991-05-18

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