FR2405940A2 - Nouveaux derives de la benzophenone, leur procede de preparation et leur application comme medicament - Google Patents

Nouveaux derives de la benzophenone, leur procede de preparation et leur application comme medicament

Info

Publication number
FR2405940A2
FR2405940A2 FR7731164A FR7731164A FR2405940A2 FR 2405940 A2 FR2405940 A2 FR 2405940A2 FR 7731164 A FR7731164 A FR 7731164A FR 7731164 A FR7731164 A FR 7731164A FR 2405940 A2 FR2405940 A2 FR 2405940A2
Authority
FR
France
Prior art keywords
phenyl
derivs
benzophenone
alkyl
alkanoate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7731164A
Other languages
English (en)
Other versions
FR2405940B2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7731164A priority Critical patent/FR2405940A2/fr
Priority to SE7712447A priority patent/SE7712447L/xx
Priority to US05/869,361 priority patent/US4147790A/en
Priority to PT67549A priority patent/PT67549B/fr
Priority to IE140/78A priority patent/IE46496B1/en
Priority to NL7800716A priority patent/NL7800716A/xx
Priority to CA295,579A priority patent/CA1105022A/fr
Priority to DK28478A priority patent/DK145182C/da
Priority to DE19782802519 priority patent/DE2802519A1/de
Priority to JP444278A priority patent/JPS5395986A/ja
Priority to GB2343/78A priority patent/GB1567879A/en
Priority to ES466206A priority patent/ES466206A1/es
Priority to LU78924A priority patent/LU78924A1/fr
Priority to HU78RO960A priority patent/HU179576B/hu
Priority to CH66378A priority patent/CH627750A5/fr
Priority to AU32645/78A priority patent/AU514297B2/en
Publication of FR2405940A2 publication Critical patent/FR2405940A2/fr
Application granted granted Critical
Publication of FR2405940B2 publication Critical patent/FR2405940B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention a pour objet les composés répondant à la formule 1 de la revendication 1 de la demande de brevet principal dont les noms suivent : - le 3-(4-chlorobenzoyl) benzène acétate de 2-/4-/3-(trifluorométhyle) phényl/1-pipérazinyl/ éthyle; - la 3-(4-chlorobenzoyl) 2-méthyl benzène hexanoate de 2-/4-/3-trifluorométhyl) phényl/1-pipérazinyl/éthyle; - le 3-(4-chlorobenzoyl)benzène acétate de 2-/4-/4-(chloro) phinyl/1-pipérazinyl/éthyle; ainsi que leurs sels d'addition avec les acides et notamment leur chlorhydrate. Les composés de formule I présentent d'intéressantes propriétés pharmacologiques, qui justifient leur utilisation comme médicament
FR7731164A 1977-01-21 1977-10-17 Nouveaux derives de la benzophenone, leur procede de preparation et leur application comme medicament Granted FR2405940A2 (fr)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FR7731164A FR2405940A2 (fr) 1977-10-17 1977-10-17 Nouveaux derives de la benzophenone, leur procede de preparation et leur application comme medicament
SE7712447A SE7712447L (sv) 1977-01-21 1977-11-03 Sett att framstella nya bensofenonderivat
US05/869,361 US4147790A (en) 1977-01-21 1978-01-13 (4-Phenyl-piperazino alkyl)-3-benzoyl-benzene alkanoates
PT67549A PT67549B (fr) 1977-01-21 1978-01-19 Procede de preparation de nouveaux derives de la benzophenone
ES466206A ES466206A1 (es) 1977-01-21 1978-01-20 Un procedimiento de preparacion de nuevos derivados de la benzofenona.
CA295,579A CA1105022A (fr) 1977-01-21 1978-01-20 Procede de preparation de nouveaux derives de la benzophenone
DK28478A DK145182C (da) 1977-01-21 1978-01-20 Analogifremgangsmaade til fremstilling af benzoylphenyleddikesyrepiperazinylethylestere eller additionssalte deraf med syrer
DE19782802519 DE2802519A1 (de) 1977-01-21 1978-01-20 Neue benzophenonderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
IE140/78A IE46496B1 (en) 1977-01-21 1978-01-20 New benzophenone derivatives,processes for preparing them and pharmaceutical compositions containing them
GB2343/78A GB1567879A (en) 1977-01-21 1978-01-20 Benzophenone derivatives processes for preparing them and pharmaceutical compositions containing them
NL7800716A NL7800716A (nl) 1977-01-21 1978-01-20 Nieuwe benzofenonderivaten, farmaceutische pre- paraten, die deze benzofenonderivaten bevatten, en werkwijzen ter bereiding daarvan.
LU78924A LU78924A1 (fr) 1977-01-21 1978-01-20 Procede de preparation de nouveaux derives de la benzophenone
HU78RO960A HU179576B (en) 1977-01-21 1978-01-20 Process for producing benzophenone derivatives
CH66378A CH627750A5 (fr) 1977-01-21 1978-01-20 Derives de la benzophenone, procede de preparation et compositions pharmaceutiques.
JP444278A JPS5395986A (en) 1977-01-21 1978-01-20 Novel benzophenone derivative* method for its production and phermaceutical composition
AU32645/78A AU514297B2 (en) 1977-01-21 1978-01-23 Benzophenone derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7731164A FR2405940A2 (fr) 1977-10-17 1977-10-17 Nouveaux derives de la benzophenone, leur procede de preparation et leur application comme medicament

Publications (2)

Publication Number Publication Date
FR2405940A2 true FR2405940A2 (fr) 1979-05-11
FR2405940B2 FR2405940B2 (fr) 1980-04-18

Family

ID=9196584

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7731164A Granted FR2405940A2 (fr) 1977-01-21 1977-10-17 Nouveaux derives de la benzophenone, leur procede de preparation et leur application comme medicament

Country Status (1)

Country Link
FR (1) FR2405940A2 (fr)

Also Published As

Publication number Publication date
FR2405940B2 (fr) 1980-04-18

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