ATE148454T1 - Neuen vitamin d derivate - Google Patents

Neuen vitamin d derivate

Info

Publication number
ATE148454T1
ATE148454T1 AT94903741T AT94903741T ATE148454T1 AT E148454 T1 ATE148454 T1 AT E148454T1 AT 94903741 T AT94903741 T AT 94903741T AT 94903741 T AT94903741 T AT 94903741T AT E148454 T1 ATE148454 T1 AT E148454T1
Authority
AT
Austria
Prior art keywords
pct
compounds
thiol
sec
derivatives
Prior art date
Application number
AT94903741T
Other languages
English (en)
Inventor
Gunnar Grue-Sorensen
Erik Rytter Ottosen
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Application granted granted Critical
Publication of ATE148454T1 publication Critical patent/ATE148454T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT94903741T 1992-12-23 1993-12-17 Neuen vitamin d derivate ATE148454T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929226877A GB9226877D0 (en) 1992-12-23 1992-12-23 Chemical compounds

Publications (1)

Publication Number Publication Date
ATE148454T1 true ATE148454T1 (de) 1997-02-15

Family

ID=10727157

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94903741T ATE148454T1 (de) 1992-12-23 1993-12-17 Neuen vitamin d derivate

Country Status (15)

Country Link
US (1) US5554599A (de)
EP (1) EP0675878B1 (de)
KR (1) KR100295977B1 (de)
AT (1) ATE148454T1 (de)
AU (1) AU668638B2 (de)
CA (1) CA2146775C (de)
DE (1) DE69307929T2 (de)
DK (1) DK0675878T3 (de)
ES (1) ES2098123T3 (de)
FI (1) FI108225B (de)
GB (1) GB9226877D0 (de)
GR (1) GR3022774T3 (de)
NZ (1) NZ259317A (de)
RU (1) RU2136660C1 (de)
WO (1) WO1994014766A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830885A (en) * 1992-03-12 1998-11-03 The Johns Hopkins University Antiproliferative vitamin D3 hybrids
US6407082B1 (en) * 1996-09-13 2002-06-18 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a vitamin D compound
US20040167106A1 (en) * 1993-06-04 2004-08-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of a Vitamin D compound
GB9314400D0 (en) * 1993-07-12 1993-08-25 Leo Pharm Prod Ltd Produktionsaktieselskab) chemical compounds
WO1995027697A1 (en) * 1994-04-11 1995-10-19 Chugai Seiyaku Kabushiki Kaisha 22-thiavitamin d3 derivative
ATE290869T1 (de) 1995-12-28 2005-04-15 Chugai Pharmaceutical Co Ltd Verwendung von vitamin d derivaten zur herstellung eines medikaments zur behandlung von bösartigen tumormetastase
US6869940B2 (en) 1995-12-28 2005-03-22 Chugai Seiyaku Kabushiki Kaisha Malignant tumor metastasis inhibitors
US6765002B2 (en) 2000-03-21 2004-07-20 Gustavo Rodriguez Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6034074A (en) 1996-09-13 2000-03-07 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a Vitamin D compound
US6028064A (en) 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
US6511970B1 (en) 1996-09-13 2003-01-28 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6184398B1 (en) 1996-12-20 2001-02-06 Chugai Seiyaku Kabushiki Kaisha 16-ene-vitamin D derivatives
CA2275382A1 (en) * 1996-12-20 1998-07-02 Chugai Seiyaku Kabushiki Kaisha 16-ene-vitamin d derivatives
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
ES2274785T3 (es) 1999-04-01 2007-06-01 Johns Hopkins University Analogos de 1-alfa,25-dihidroxi vitamina d3 no calcemicos, antiproliferativos, transcripcionalmente activos que contienen azufre.
DK1220676T3 (da) 1999-09-29 2005-09-05 Colotech As Forebyggelse af colorektal cancer
US6703380B2 (en) 1999-09-29 2004-03-09 Colotech A/S Prevention of cancer
WO2001030751A2 (en) * 1999-10-25 2001-05-03 Strakan Limited USES OF 1,25-DIHYDROXY-5,6-trans VITAMIN D COMPOUNDS AND DERIVATIVES THEREOF
US20010044431A1 (en) * 2000-03-21 2001-11-22 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
JP4803939B2 (ja) 2000-04-19 2011-10-26 中外製薬株式会社 ビタミンｄ誘導体
CN100469764C (zh) * 2000-06-15 2009-03-18 中外制药株式会社 维生素d衍生物
ATE428692T1 (de) * 2001-08-22 2009-05-15 Univ Johns Hopkins 24-schwefel-substituierte 1-alpha-25-dihydroxy- vitamin-d3-analogen
HRP20070058B1 (hr) 2001-10-19 2014-05-23 Isotechnika Inc. Sinteza ciklosporinskih analoga
US7101865B2 (en) 2002-06-13 2006-09-05 Cytochroma Inc. 24-sulfoximine vitamin D3 compounds
CA2510228C (en) 2002-12-18 2012-10-30 Johns Hopkins University 25-so2-substituted analogs of 1.alpha.,25-dihydroxyvitamin d3
SG173119A1 (en) 2009-01-27 2011-08-29 Berg Biosystems Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
MX366076B (es) 2009-08-14 2019-06-27 Berg Llc Vitamina d3 y analogos de la misma para tratar alopecia.
SG10201709894RA (en) 2013-05-29 2018-01-30 Berg Llc Preventing or mitigating chemotherapy induced alopecia using vitamin d

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4749710A (en) * 1985-05-01 1988-06-07 Hoffmann-La Roche Inc. Immunosuppressive agents
SU1445729A1 (ru) * 1986-04-08 1988-12-23 Харьковский научно-исследовательский институт дерматологии и венерологии Способ лечени псориаза
FR2631025B1 (fr) * 1988-05-04 1991-04-12 Ire Medgenix Sa Nouveaux derives de la vitamine d3 et application aux dosages des metabolites de la vitamine d3
GB8904153D0 (en) * 1989-02-23 1989-04-05 Leo Pharm Prod Ltd Chemical compounds
WO1995027697A1 (en) * 1994-04-11 1995-10-19 Chugai Seiyaku Kabushiki Kaisha 22-thiavitamin d3 derivative

Also Published As

Publication number Publication date
DE69307929D1 (de) 1997-03-13
RU2136660C1 (ru) 1999-09-10
ES2098123T3 (es) 1997-04-16
CA2146775C (en) 2005-06-28
KR950703501A (ko) 1995-09-20
AU5808794A (en) 1994-07-19
EP0675878A1 (de) 1995-10-11
RU95113480A (ru) 1997-03-20
GR3022774T3 (en) 1997-06-30
KR100295977B1 (ko) 2001-11-14
CA2146775A1 (en) 1994-07-07
DE69307929T2 (de) 1997-09-04
AU668638B2 (en) 1996-05-09
FI952972A0 (fi) 1995-06-16
DK0675878T3 (da) 1997-04-28
WO1994014766A1 (en) 1994-07-07
FI108225B (fi) 2001-12-14
EP0675878B1 (de) 1997-01-29
NZ259317A (en) 1997-05-26
US5554599A (en) 1996-09-10
GB9226877D0 (en) 1993-02-17
FI952972L (fi) 1995-06-16

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee