FR2665901B2 - Nouveaux 19-nor sterouides ayant en position 11beta une chaine carbonee comportant une fonction amide, leur preparation, leur application comme medicaments. - Google Patents

Nouveaux 19-nor sterouides ayant en position 11beta une chaine carbonee comportant une fonction amide, leur preparation, leur application comme medicaments.

Info

Publication number
FR2665901B2
FR2665901B2 FR9010323A FR9010323A FR2665901B2 FR 2665901 B2 FR2665901 B2 FR 2665901B2 FR 9010323 A FR9010323 A FR 9010323A FR 9010323 A FR9010323 A FR 9010323A FR 2665901 B2 FR2665901 B2 FR 2665901B2
Authority
FR
France
Prior art keywords
sterouides
11beta
medicaments
preparation
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9010323A
Other languages
English (en)
Other versions
FR2665901A2 (fr
Inventor
Roussel-Uclaf Socie Directoire
Conseil De Surveillance
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8902384A external-priority patent/FR2643638B1/fr
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR9010323A priority Critical patent/FR2665901B2/fr
Priority to AT91402214T priority patent/ATE162797T1/de
Priority to DK91402214T priority patent/DK0471612T3/da
Priority to DE69128820T priority patent/DE69128820T2/de
Priority to ES91402214T priority patent/ES2112268T3/es
Priority to EP91402214A priority patent/EP0471612B1/fr
Priority to MX9100647A priority patent/MX9100647A/es
Priority to IE286391A priority patent/IE912863A1/en
Priority to KR1019910013914A priority patent/KR920004408A/ko
Priority to HU912690A priority patent/HUT59416A/hu
Priority to CA002049102A priority patent/CA2049102A1/fr
Priority to JP03226410A priority patent/JP3073803B2/ja
Priority to PT98681A priority patent/PT98681B/pt
Priority to ZA916420A priority patent/ZA916420B/xx
Priority to AU82422/91A priority patent/AU644671B2/en
Publication of FR2665901A2 publication Critical patent/FR2665901A2/fr
Priority to US08/068,735 priority patent/US5707982A/en
Publication of FR2665901B2 publication Critical patent/FR2665901B2/fr
Application granted granted Critical
Priority to US08/442,957 priority patent/US6790971B1/en
Priority to GR970402371T priority patent/GR3026315T3/el
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
FR9010323A 1989-02-24 1990-08-14 Nouveaux 19-nor sterouides ayant en position 11beta une chaine carbonee comportant une fonction amide, leur preparation, leur application comme medicaments. Expired - Lifetime FR2665901B2 (fr)

Priority Applications (18)

Application Number Priority Date Filing Date Title
FR9010323A FR2665901B2 (fr) 1989-02-24 1990-08-14 Nouveaux 19-nor sterouides ayant en position 11beta une chaine carbonee comportant une fonction amide, leur preparation, leur application comme medicaments.
AT91402214T ATE162797T1 (de) 1990-08-14 1991-08-09 Neue 19-nor steroide, die eine amid tragende gruppe in der 11-beta-stelle haben, ihre herstellung, ihre verwendung als medikamente und pharmazeutische präparate davon
DK91402214T DK0471612T3 (da) 1990-08-14 1991-08-09 Nye 19-nor steroider med carbonkæde omfattende en amidgruppe i 11-beta-stillingen, fremgangsmåde til deres fremstilling, de
DE69128820T DE69128820T2 (de) 1990-08-14 1991-08-09 Neue 19-Nor Steroide, die eine Amid tragende Gruppe in der 11-Beta-Stelle haben, ihre Herstellung, ihre Verwendung als Medikamente und pharmazeutische Präparate davon
ES91402214T ES2112268T3 (es) 1990-08-14 1991-08-09 Nuevos 19-nor-esteroides que tienen en posicion 11beta una cadena carbonada que comprende una funcion amida, su preparacion, su aplicacion como medicamentos y composiciones farmaceuticas que los contienen.
EP91402214A EP0471612B1 (fr) 1990-08-14 1991-08-09 Nouveaux 19-Nor stéroides ayant en position 11béta une chaíne carbonée comportant une fonction amide, leur préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant
HU912690A HUT59416A (en) 1990-08-14 1991-08-13 Process for producing new 19-norsteroid derivatives carrying carbon chain comprising amido group in 11beta position and pharmaceutical compositions comprising same
JP03226410A JP3073803B2 (ja) 1990-08-14 1991-08-13 アミド官能基を含有する炭素鎖を１１β位置に有する新規の１９−ノルステロイド、それらの製造方法、それらの薬剤としての使用及びそれらを含有する製薬組成物
IE286391A IE912863A1 (en) 1990-08-14 1991-08-13 New 19-nor steroids having a carbonated chain containing an¹amide function in position 11beta, their preparation, their¹use as medicaments and the pharmaceutical compositions¹containing them
KR1019910013914A KR920004408A (ko) 1990-08-14 1991-08-13 11베타 위치에 아미드 작용기를 함유한 카르본화 쇄를 갖는 신규 19-노르 스테로이드, 그의 제조 방법, 의약으로서의 그의 용도 및 그를 함유하는 제약 조성물
MX9100647A MX9100647A (es) 1990-08-14 1991-08-13 Nuevos 19-nor-esteroides que tienen en posicion ii beta una cadena carbonada que contiene una funcion amida,su preparacion,su aplicacion como medicamentos y las composiciones farmaceuticas que los contienen
CA002049102A CA2049102A1 (fr) 1990-08-14 1991-08-13 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide, leur preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
PT98681A PT98681B (pt) 1990-08-14 1991-08-14 Processo para a preparacao de novos 19-nor esteroides que tem na posicao 11b uma cadeia de atomos de carbono com uma funcao amida e de composicoes farmaceuticas que os contem
ZA916420A ZA916420B (en) 1990-08-14 1991-08-14 19-nor steroids having a carbonated chain containing an amide function in position 11 beta,their preparation,their use as medicaments and the pharmaceutical compositions containing them
AU82422/91A AU644671B2 (en) 1990-08-14 1991-08-14 New 19-NOR steroids having a carbonated chain containing an amide function in position 11beta, their preparation, their use as medicaments and the pharmaceutical compositions containing them
US08/068,735 US5707982A (en) 1989-02-24 1993-05-28 19-nor-steroids
US08/442,957 US6790971B1 (en) 1989-02-24 1995-05-17 19-Nor-steroids
GR970402371T GR3026315T3 (en) 1990-08-14 1998-03-11 New steroids having an amide substituted group in the 11-beta position, their preparation, their use as medicines and pharmaceutical composition thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8902384A FR2643638B1 (fr) 1989-02-24 1989-02-24 Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR9010323A FR2665901B2 (fr) 1989-02-24 1990-08-14 Nouveaux 19-nor sterouides ayant en position 11beta une chaine carbonee comportant une fonction amide, leur preparation, leur application comme medicaments.

Publications (2)

Publication Number Publication Date
FR2665901A2 FR2665901A2 (fr) 1992-02-21
FR2665901B2 true FR2665901B2 (fr) 1994-07-29

Family

ID=26227181

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9010323A Expired - Lifetime FR2665901B2 (fr) 1989-02-24 1990-08-14 Nouveaux 19-nor sterouides ayant en position 11beta une chaine carbonee comportant une fonction amide, leur preparation, leur application comme medicaments.

Country Status (1)

Country Link
FR (1) FR2665901B2 (fr)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2235949B1 (fr) * 1973-06-18 1978-03-17 Roussel Uclaf
FR2522328B1 (fr) * 1982-03-01 1986-02-14 Roussel Uclaf Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments
AU580843B2 (en) * 1985-02-07 1989-02-02 Schering Aktiengesellschaft 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them
GB8513723D0 (en) * 1985-05-31 1985-07-03 Erba Farmitalia 11-beta substituted steroids
DE3621024C2 (de) * 1986-06-20 1999-10-28 Schering Ag 11beta-Phenylestradiene, deren Herstellung und diese enthaltende pharmazeutische Präparate
FR2620707B1 (fr) * 1987-09-18 1989-12-08 Roussel Uclaf Nouveaux steroides comportant un cycle spirannique a 3, 4 ou 6 chainons en position 17, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
FR2665901A2 (fr) 1992-02-21

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