FR2677372B1 - Sequences nucleotidiques et peptidiques d'un isolat de virus de l'hepatite c, applications diagnostiques et therapeutiques. - Google Patents

Sequences nucleotidiques et peptidiques d'un isolat de virus de l'hepatite c, applications diagnostiques et therapeutiques.

Info

Publication number
FR2677372B1
FR2677372B1 FR9106882A FR9106882A FR2677372B1 FR 2677372 B1 FR2677372 B1 FR 2677372B1 FR 9106882 A FR9106882 A FR 9106882A FR 9106882 A FR9106882 A FR 9106882A FR 2677372 B1 FR2677372 B1 FR 2677372B1
Authority
FR
France
Prior art keywords
hepatitis
nucleotide
diagnostic
peptide sequences
therapeutic applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9106882A
Other languages
English (en)
Other versions
FR2677372A1 (fr
Inventor
Christian Brechot
Dina Kremsdorf
Colette Porchon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur
Original Assignee
Institut Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9106882A priority Critical patent/FR2677372B1/fr
Application filed by Institut Pasteur filed Critical Institut Pasteur
Priority to PCT/FR1992/000501 priority patent/WO1992021759A1/fr
Priority to US07/965,285 priority patent/US5879904A/en
Priority to CA002088666A priority patent/CA2088666A1/fr
Priority to JP4510772A priority patent/JPH06500698A/ja
Priority to EP92911801A priority patent/EP0542970A1/fr
Publication of FR2677372A1 publication Critical patent/FR2677372A1/fr
Application granted granted Critical
Publication of FR2677372B1 publication Critical patent/FR2677372B1/fr
Priority to US08/487,231 priority patent/US5919454A/en
Priority to US09/201,912 priority patent/US6210962B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FR9106882A 1991-06-06 1991-06-06 Sequences nucleotidiques et peptidiques d'un isolat de virus de l'hepatite c, applications diagnostiques et therapeutiques. Expired - Lifetime FR2677372B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR9106882A FR2677372B1 (fr) 1991-06-06 1991-06-06 Sequences nucleotidiques et peptidiques d'un isolat de virus de l'hepatite c, applications diagnostiques et therapeutiques.
US07/965,285 US5879904A (en) 1991-06-06 1992-06-04 Nucleotide and peptide sequences of a hepatitis C virus isolate, diagnostic and therapeutic applications
CA002088666A CA2088666A1 (fr) 1991-06-06 1992-06-04 Sequences nucleotidiques et peptidiques d'un isolat de virus de l'hepatite c, applications diagnostiques et therapeutiques
JP4510772A JPH06500698A (ja) 1991-06-06 1992-06-04 Ｃ型肝炎ウィルス単離物のヌクレオチド及びペプチド、診断及び治療用途
PCT/FR1992/000501 WO1992021759A1 (fr) 1991-06-06 1992-06-04 Sequences nucleotidiques et peptidiques d'un isolat de virus de l'hepatite c, applications diagnostiques et therapeutiques
EP92911801A EP0542970A1 (fr) 1991-06-06 1992-06-04 Sequences nucleotidiques et peptidiques d'un isolat de virus de l'hepatite c, applications diagnostiques et therapeutiques
US08/487,231 US5919454A (en) 1991-06-06 1995-06-07 Nucleotide and peptide sequences of a hepatitis C virus isolate, diagnostic and therapeutic applications
US09/201,912 US6210962B1 (en) 1991-06-06 1998-11-30 Nucleotide and peptide sequences of an isolate of the hepatitis C virus, diagnostic and therapeutic applications thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9106882A FR2677372B1 (fr) 1991-06-06 1991-06-06 Sequences nucleotidiques et peptidiques d'un isolat de virus de l'hepatite c, applications diagnostiques et therapeutiques.

Publications (2)

Publication Number Publication Date
FR2677372A1 FR2677372A1 (fr) 1992-12-11
FR2677372B1 true FR2677372B1 (fr) 1994-11-10

Family

ID=9413551

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9106882A Expired - Lifetime FR2677372B1 (fr) 1991-06-06 1991-06-06 Sequences nucleotidiques et peptidiques d'un isolat de virus de l'hepatite c, applications diagnostiques et therapeutiques.

Country Status (6)

Country Link
US (3) US5879904A (fr)
EP (1) EP0542970A1 (fr)
JP (1) JPH06500698A (fr)
CA (1) CA2088666A1 (fr)
FR (1) FR2677372B1 (fr)
WO (1) WO1992021759A1 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2677372B1 (fr) 1991-06-06 1994-11-10 Pasteur Institut Sequences nucleotidiques et peptidiques d'un isolat de virus de l'hepatite c, applications diagnostiques et therapeutiques.
ES2188583T3 (es) 1991-06-24 2003-07-01 Chiron Corp Polipeptidos para el virus de la hepatitis c (hcv).
US5866139A (en) * 1992-06-04 1999-02-02 Institut Pasteur Nucleotide and peptide sequences of a hepatitis C virus isolate, diagnostic and therapeutic applications
US7070790B1 (en) 1993-06-29 2006-07-04 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 and core genes of isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US5882852A (en) * 1993-06-29 1999-03-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Hepatitic C virus (HCV) core gene nucleotide sequences and related methods of detecting major and minor genotypes of HCV isolates
US5514539A (en) * 1993-06-29 1996-05-07 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines
US20040185061A1 (en) * 1994-07-29 2004-09-23 Innogenetics N.V. Redox reversible HCV proteins with native-like conformation
ES2174957T5 (es) * 1994-07-29 2006-12-16 Innogenetics N.V. Proteinas purificadas de envoltura de virus de la hepatitis c para uso diagnostico y terapeutico.
US5674681A (en) * 1994-12-06 1997-10-07 Rothenberg; Barry E. Methods to identify hemochromatosis
US6538114B1 (en) * 1996-04-19 2003-03-25 Karolina Innovations Ab Human monoclonal antibodies specific for hepatitis C virus (HCV) E2 antigen
US6747136B2 (en) * 1996-04-19 2004-06-08 Karolinska Innovations Ab Human monoclonal antibodies specific for hepatitis C virus (HCV) E2 antigen
EP0947525A1 (fr) * 1998-03-27 1999-10-06 Innogenetics N.V. Epitopes de protéines d'enveloppe virale et anticorps spécifiques pour cet epitope: usage pour le diagnostic de l'antigène de virus HCV dans le tissu hÔte
US7108855B2 (en) * 1998-06-24 2006-09-19 Innogenetics N.V. Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use
KR100282147B1 (ko) * 1998-11-13 2001-02-15 구자홍 압축 영상 복원 방법
US6355425B1 (en) * 1999-03-26 2002-03-12 Billups-Rothenberg, Inc. Mutations associated with iron disorders
JP5175417B2 (ja) * 2000-08-17 2013-04-03 トリペップ アクチ ボラゲット リバビリンを含むワクチンおよびその使用方法
US6858590B2 (en) * 2000-08-17 2005-02-22 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US7022830B2 (en) * 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
US6680059B2 (en) * 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
US7101561B2 (en) 2000-12-01 2006-09-05 Innogenetics N.V. Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use
WO2002090572A2 (fr) * 2001-05-09 2002-11-14 Third Wave Technologies, Inc. Detection d'acides nucleiques dans des echantillons groupes
KR100457790B1 (ko) * 2001-08-08 2004-12-08 충남대학교산학협력단 감염성을 갖는 ｈｃｖ 유사입자의 제조
CA2618429A1 (fr) * 2005-05-25 2007-03-22 Tripep Ab Gene de fusion ns3/4a non structurel de l'hepatite c
WO2007111964A2 (fr) * 2006-03-22 2007-10-04 Genimmune N.V. Anticorps neutralisant le virus de l'hépatite c
JP5642972B2 (ja) 2007-02-21 2014-12-17 ユニバーシティー オブ マサチューセッツＵｎｉｖｅｒｓｉｔｙ ｏｆ Ｍａｓｓａｃｈｕｓｅｔｔｓ Ｃ型肝炎ウイルス（ｈｃｖ）に対するヒト抗体およびその使用
US8071561B2 (en) * 2007-08-16 2011-12-06 Chrontech Pharma Ab Immunogen platform
US20090214593A1 (en) * 2007-08-16 2009-08-27 Tripep Ab Immunogen platform
WO2009034190A2 (fr) * 2007-09-14 2009-03-19 Genimmune N.V. Marqueur d'affinité
US20100104555A1 (en) * 2008-10-24 2010-04-29 The Scripps Research Institute HCV neutralizing epitopes
US9402454B2 (en) 2010-04-21 2016-08-02 James Landy Fluid application device
US10550379B2 (en) 2015-06-29 2020-02-04 The Board Of Trustees Of The Leland Stanford Junior University Degron fusion constructs and methods for controlling protein production

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02500880A (ja) * 1987-11-18 1990-03-29 カイロン　コーポレイション Ｎａｎｂｖの診断用薬およびワクチン
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens
WO1990000597A1 (fr) * 1988-07-06 1990-01-25 Genelabs Incorporated Virus et antigenes d'hepatite serique non a et n b
KR0185373B1 (ko) * 1989-03-17 1999-05-01 로버트 피. 블랙버언 Hcv 폴리단백질에서 유래되는 hcv 아미노산 서열 부분을 포함하는 폴리펩티드 및 그 사용
ATE211772T1 (de) * 1989-05-18 2002-01-15 Chiron Corp Nanbv-diagnostika: polynukleotide, geeignet für reihenuntersuchungen auf hepatitis c-virus
FR2677372B1 (fr) 1991-06-06 1994-11-10 Pasteur Institut Sequences nucleotidiques et peptidiques d'un isolat de virus de l'hepatite c, applications diagnostiques et therapeutiques.

Also Published As

Publication number Publication date
US5879904A (en) 1999-03-09
FR2677372A1 (fr) 1992-12-11
WO1992021759A1 (fr) 1992-12-10
EP0542970A1 (fr) 1993-05-26
US5919454A (en) 1999-07-06
JPH06500698A (ja) 1994-01-27
US6210962B1 (en) 2001-04-03
CA2088666A1 (fr) 1992-12-07

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