FR2696190B1 - Acide nucléique codant pour une alpha-acétolactate synthase et ses applications. - Google Patents

Acide nucléique codant pour une alpha-acétolactate synthase et ses applications.

Info

Publication number
FR2696190B1
FR2696190B1 FR9211470A FR9211470A FR2696190B1 FR 2696190 B1 FR2696190 B1 FR 2696190B1 FR 9211470 A FR9211470 A FR 9211470A FR 9211470 A FR9211470 A FR 9211470A FR 2696190 B1 FR2696190 B1 FR 2696190B1
Authority
FR
France
Prior art keywords
alpha
nucleic acid
acetolactate synthase
pct
acid coding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9211470A
Other languages
English (en)
Other versions
FR2696190A1 (fr
Inventor
Stanislav Ehrlich
Pierre Godon Jean-Jacquesrenau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Recherche Agronomique INRA
Original Assignee
Institut National de la Recherche Agronomique INRA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9211470A priority Critical patent/FR2696190B1/fr
Application filed by Institut National de la Recherche Agronomique INRA filed Critical Institut National de la Recherche Agronomique INRA
Priority to DE69316234T priority patent/DE69316234D1/de
Priority to AT93921008T priority patent/ATE161887T1/de
Priority to PCT/GB1993/002012 priority patent/WO1994008020A1/fr
Priority to EP93921008A priority patent/EP0667907B1/fr
Priority to DK93921008T priority patent/DK0667907T3/da
Priority to US08/403,866 priority patent/US5643779A/en
Publication of FR2696190A1 publication Critical patent/FR2696190A1/fr
Application granted granted Critical
Publication of FR2696190B1 publication Critical patent/FR2696190B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
FR9211470A 1992-09-25 1992-09-25 Acide nucléique codant pour une alpha-acétolactate synthase et ses applications. Expired - Fee Related FR2696190B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR9211470A FR2696190B1 (fr) 1992-09-25 1992-09-25 Acide nucléique codant pour une alpha-acétolactate synthase et ses applications.
AT93921008T ATE161887T1 (de) 1992-09-25 1993-09-27 Nukleinsäure, die für eine alpha- acetolaktatsynthase aus lactococcus kodieren und dessen verwendung
PCT/GB1993/002012 WO1994008020A1 (fr) 1992-09-25 1993-09-27 ACIDE NUCLEIQUE CODANT POUR UNE α-ACETOLACTATE SYNTHASE ET SES APPLICATIONS
EP93921008A EP0667907B1 (fr) 1992-09-25 1993-09-27 ACIDE NUCLEIQUE CODANT POUR UNE $g(a)-ACETOLACTATE SYNTHASE ET SES APPLICATIONS
DE69316234T DE69316234D1 (de) 1992-09-25 1993-09-27 Nukleinsäure, die für eine alpha-acetolaktatsynthase aus lactococcus kodieren und dessen verwendung
DK93921008T DK0667907T3 (da) 1992-09-25 1993-09-27 Nukleinsyre kodende for en alfa-acetolactat-syntase fra Lactococcus og anvendelse deraf
US08/403,866 US5643779A (en) 1992-09-25 1993-09-27 Nucleic acid coding for an α-acetolactate synthase from lactococcus and its applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9211470A FR2696190B1 (fr) 1992-09-25 1992-09-25 Acide nucléique codant pour une alpha-acétolactate synthase et ses applications.

Publications (2)

Publication Number Publication Date
FR2696190A1 FR2696190A1 (fr) 1994-04-01
FR2696190B1 true FR2696190B1 (fr) 1994-12-09

Family

ID=9433906

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9211470A Expired - Fee Related FR2696190B1 (fr) 1992-09-25 1992-09-25 Acide nucléique codant pour une alpha-acétolactate synthase et ses applications.

Country Status (7)

Country Link
US (1) US5643779A (fr)
EP (1) EP0667907B1 (fr)
AT (1) ATE161887T1 (fr)
DE (1) DE69316234D1 (fr)
DK (1) DK0667907T3 (fr)
FR (1) FR2696190B1 (fr)
WO (1) WO1994008020A1 (fr)

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US6455678B1 (en) * 1996-04-26 2002-09-24 Amcell Corporation Human hematopoietic stem and progenitor cell antigen
DK0985043T4 (en) 1997-05-30 2017-04-24 Chr Hansen As Lactic acid bacterial starter cultures and compositions thereof
US6451581B1 (en) 1997-10-28 2002-09-17 E.I. Du Pont De Nemours And Company Plant branched-chain amino acid biosynthetic enzymes
US6348643B1 (en) * 1998-10-29 2002-02-19 American Cyanamid Company DNA sequences encoding the arabidopsis acetohydroxy-acid synthase small subunit and methods of use
AU2003202378A1 (en) * 2002-02-04 2003-09-02 Affinium Pharmaceuticals, Inc. Novel purified polypeptides from staphylococcus aureus
US8278076B2 (en) 2002-02-20 2012-10-02 University Of Georgia Research Foundation, Inc. Microbial production of pyruvate and pyruvate derivatives
EP1495127A4 (fr) * 2002-02-20 2007-03-21 Univ Georgia Res Found Preparation microbienne de pyruvate et d'autres metabolites
BRPI0413917B1 (pt) * 2003-08-29 2018-09-25 Instituto Nacional De Tech Agropecuaria ácido nucleico ahas de arroz mutagenizado não transgênico, polipeptídeo ahas isolado, e, método de controle de ervas daninhas dentro da vizinhança de uma planta de arroz
CN101031646B (zh) * 2004-07-30 2013-09-25 巴斯夫农业化学产品公司 抗除草剂的向日葵植物、编码抗除草剂的乙酰羟酸合酶大亚基蛋白的多核苷酸和使用方法
EP3581024A1 (fr) * 2005-03-02 2019-12-18 Instituto Nacional de Tecnologia Agropecuaria Plantes de riz résistantes aux herbicides, polynucléotides codant pour la résistance aux herbicides, protéines à grandes sous-unités d'acétohydroxyacide synthase et procédés d'utilisation
CN101287836B (zh) * 2005-07-01 2013-02-20 巴斯福股份公司 抗除草剂的向日葵植物、编码抗除草剂的乙酰羟酸合酶大亚基蛋白的多核苷酸和使用方法
US8945899B2 (en) 2007-12-20 2015-02-03 Butamax Advanced Biofuels Llc Ketol-acid reductoisomerase using NADH
UA108733C2 (uk) 2006-12-12 2015-06-10 Толерантна до гербіциду рослина соняшника
US10017827B2 (en) 2007-04-04 2018-07-10 Nidera S.A. Herbicide-resistant sunflower plants with multiple herbicide resistant alleles of AHASL1 and methods of use
CN101680007A (zh) 2007-04-18 2010-03-24 纳幕尔杜邦公司 使用高活性酮醇酸还原异构酶来发酵生产异丁醇
BRPI0909989A2 (pt) 2008-06-05 2021-06-22 Butamax Advanced Biofuels Llc célula de levedura recombinante e método para a produção de um produto
ES2521675T3 (es) * 2008-09-29 2014-11-13 Butamax Advanced Biofuels Llc Identificación y uso de [2Fe-2S]-dihidroxi-ácido deshidratasas bacterianas
WO2010037105A1 (fr) * 2008-09-29 2010-04-01 Butamax™ Advanced Biofuels LLC Amélioration de l’activité dihydroxy-acide déshydratase dans des bactéries de l’acide lactique
EP2464736A4 (fr) 2009-08-12 2013-07-31 Gevo Inc Localisation de la voie de l'isobutanol cytosolique pour la production d'isobutanol
IN2012DN02227A (fr) * 2009-09-29 2015-08-21 Butamax Tm Advanced Biofuels
BR112012020589B8 (pt) 2010-02-17 2021-05-18 Butamax Tm Advanced Biofuels célula hospedeira recombinante de levedura, método para fabricar um produto, método para converter 2,3-diidroxiisovalerato em alfa-cetoisovalerato, método para aumentar a atividade específica de um polipeptídeo heterólogo, método para aumentar o fluxo em uma via biossintética e método para aumentar a atividade de uma proteína
WO2012129555A2 (fr) 2011-03-24 2012-09-27 Butamax (Tm) Advanced Biofuels Llc Cellules hôtes et procédés de production d'isobutanol
CN104619835B (zh) 2012-05-11 2018-06-19 布特马斯先进生物燃料有限责任公司 酮醇酸还原异构酶及其使用方法
CA2886157A1 (fr) 2012-09-26 2014-04-03 Butamax Advanced Biofuels Llc Polypeptides ayant une activite cetol-acide reducto-isomerase
US9650624B2 (en) 2012-12-28 2017-05-16 Butamax Advanced Biofuels Llc DHAD variants for butanol production
WO2014151190A1 (fr) 2013-03-15 2014-09-25 Butamax Advanced Biofuels Llc Variants de dhad et procédés de criblage

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3942947A1 (de) * 1989-12-23 1991-06-27 Forschungszentrum Juelich Gmbh Verfahren zur herstellung von l-isoleucin und dafuer geeignete mikroorganismen und rekombinante dna
CA2061689C (fr) * 1991-02-22 2000-11-07 John David Marugg Methode de preparation d'acide alpha-acetolactique

Also Published As

Publication number Publication date
EP0667907A1 (fr) 1995-08-23
EP0667907B1 (fr) 1998-01-07
DK0667907T3 (da) 1998-09-07
US5643779A (en) 1997-07-01
ATE161887T1 (de) 1998-01-15
DE69316234D1 (de) 1998-02-12
WO1994008020A1 (fr) 1994-04-14
FR2696190A1 (fr) 1994-04-01

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